Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/clWI5TF3gQ
We need to read MIND-USA, too #ICUreadings https://t.co/zp8fvCg2Gz
RT @dchristmas: Another nail in the coffin for antipsychotics in delirium? https://t.co/0Y3Ox7ciUt. Also, lack of effect in older patients…
A new treatment for delirium. Interesting work shared from @NEJM. https://t.co/4f7kuwO2p5
Another nail in the coffin for antipsychotics in delirium? https://t.co/0Y3Ox7ciUt. Also, lack of effect in older patients as well (Agar et al, 2017): https://t.co/qORJArEdwQ. We still lack effective interventions, however, and the mortality has not reduce
RT @accpcritprn: Excellent editorial by Dr. Thomas P. Bleck on the new MIND-USA trial for anti-psychotics in ICU delirium. #critPRN https:/…
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/vTzs9iEyoI
This will make me think twice about giving antipsychotics for delirium in the ICU, but I wonder it should also cause increased hesitance for use on the floor as well. I suspect so.
RT @accpcritprn: Excellent editorial by Dr. Thomas P. Bleck on the new MIND-USA trial for anti-psychotics in ICU delirium. #critPRN https:/…
Interesting newly published delirium study by Timothy Gerard, Wes Ely, et al which concluded that ICU patients given Haloperidol or Ziprasidone demonstrated no significant improvements. #health #delirium #acutecare https://t.co/kblkm6B6D1
RT @89089314: 抗精神病薬はICUせん妄に効果なし。まあ、せん妄自体が症候群的なものだろうし一様な効果は期待しないほうがいいだろうなぁ。 Haloperidol and Ziprasidone for Treatment of Delirium in Critica…
RT @89089314: 抗精神病薬はICUせん妄に効果なし。まあ、せん妄自体が症候群的なものだろうし一様な効果は期待しないほうがいいだろうなぁ。 Haloperidol and Ziprasidone for Treatment of Delirium in Critica…
RT @89089314: 抗精神病薬はICUせん妄に効果なし。まあ、せん妄自体が症候群的なものだろうし一様な効果は期待しないほうがいいだろうなぁ。 Haloperidol and Ziprasidone for Treatment of Delirium in Critica…
抗精神病薬はICUせん妄に効果なし。まあ、せん妄自体が症候群的なものだろうし一様な効果は期待しないほうがいいだろうなぁ。 Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness. - PubMed - NCBI https://t.co/WffcMuHOIR
The use of haloperidol or ziprasidone, as compared with placebo... in the ICU did not significantly alter the duration of delirium. https://t.co/cCMzTkj6EZ
RT @accpcritprn: Excellent editorial by Dr. Thomas P. Bleck on the new MIND-USA trial for anti-psychotics in ICU delirium. #critPRN https:/…
RT @accpcritprn: Excellent editorial by Dr. Thomas P. Bleck on the new MIND-USA trial for anti-psychotics in ICU delirium. #critPRN https:/…
RT @accpcritprn: Excellent editorial by Dr. Thomas P. Bleck on the new MIND-USA trial for anti-psychotics in ICU delirium. #critPRN https:/…
RT @accpcritprn: *NEW* MIND-USA Does the use of haloperidol or ziprasidone impact the duration of delirium in critically-ill? #critPRN #AC…
RT @accpcritprn: Excellent editorial by Dr. Thomas P. Bleck on the new MIND-USA trial for anti-psychotics in ICU delirium. #critPRN https:/…
Excellent editorial by Dr. Thomas P. Bleck on the new MIND-USA trial for anti-psychotics in ICU delirium. #critPRN https://t.co/sivp3XNWlr
RT @intensivecare_c: せん妄に抗精神病薬は有効か? 急性呼吸不全またはショック+せん妄患者に対する、ハロペリドール vs ziprasidone(非定型抗精神病薬) vs プラセボの比較。 抗精神病薬を使用してもせん妄の期間は短縮しないという結果。 ht…
A bit late on this one but we’re failing our pts with delirium. We know it happens, we know it’s bad and we know that it leads to mortality. But our meds don’t work! I still think non-pharm measures are the way to go but here’s hoping that one day, we’ll b
RT @intensivecare_c: せん妄に抗精神病薬は有効か? 急性呼吸不全またはショック+せん妄患者に対する、ハロペリドール vs ziprasidone(非定型抗精神病薬) vs プラセボの比較。 抗精神病薬を使用してもせん妄の期間は短縮しないという結果。 ht…
Almeno un paziente su due che riceve la ventilazione meccanica nelle terapie intensive può andare incontro ad episodi di #delirium. Le terapia intensiva prevedono oltre a protocolli per la prevenzione e monitoraggio del... https://t.co/2P2C1gcbB1
For those that want to read the study themselves #EDA2018 https://t.co/RjpwdmF6Jy
Ely: Heterogeneity of treatment effect was explored. Additional graphs can be found in Supplement of the @NEJM study #EDA2018 https://t.co/RjpwdmF6Jy https://t.co/YPWbjMkJ9T
RT @intensivecare_c: せん妄に抗精神病薬は有効か? 急性呼吸不全またはショック+せん妄患者に対する、ハロペリドール vs ziprasidone(非定型抗精神病薬) vs プラセボの比較。 抗精神病薬を使用してもせん妄の期間は短縮しないという結果。 ht…
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/nNgIR7KyFL
RT @intensivecare_c: せん妄に抗精神病薬は有効か? 急性呼吸不全またはショック+せん妄患者に対する、ハロペリドール vs ziprasidone(非定型抗精神病薬) vs プラセボの比較。 抗精神病薬を使用してもせん妄の期間は短縮しないという結果。 ht…
原病というか症状の改善がやっぱり大事なんかな?
RT @intensivecare_c: せん妄に抗精神病薬は有効か? 急性呼吸不全またはショック+せん妄患者に対する、ハロペリドール vs ziprasidone(非定型抗精神病薬) vs プラセボの比較。 抗精神病薬を使用してもせん妄の期間は短縮しないという結果。 ht…
RT @intensivecare_c: せん妄に抗精神病薬は有効か? 急性呼吸不全またはショック+せん妄患者に対する、ハロペリドール vs ziprasidone(非定型抗精神病薬) vs プラセボの比較。 抗精神病薬を使用してもせん妄の期間は短縮しないという結果。 ht…
RT @gsmartinmd: Fast forward, @timothygirard #MINDUSA study now also fails to find efficacy for drug treatment of #ICU #delirium https://…
RT @intensivecare_c: せん妄に抗精神病薬は有効か? 急性呼吸不全またはショック+せん妄患者に対する、ハロペリドール vs ziprasidone(非定型抗精神病薬) vs プラセボの比較。 抗精神病薬を使用してもせん妄の期間は短縮しないという結果。 ht…
RT @intensivecare_c: せん妄に抗精神病薬は有効か? 急性呼吸不全またはショック+せん妄患者に対する、ハロペリドール vs ziprasidone(非定型抗精神病薬) vs プラセボの比較。 抗精神病薬を使用してもせん妄の期間は短縮しないという結果。 ht…
Fast forward, @timothygirard #MINDUSA study now also fails to find efficacy for drug treatment of #ICU #delirium https://t.co/QyInKdH8IL
Proves once again that the majority of what we do does not matter #FOAMcc
Neither #haloperidol or #ziprasidone affect #delirium or #coma duration in adult medical or surgical #ICU patients with delirium vs. placebo. Most included patients had #hypoactive delirium (89%). #ABCDE bundle daily adherence was almost 90%. https://t.co
RT @timothygirard: Which is certainly possible, but at least one recent RCT examined the data carefully for evidence of heterogeneity of ef…
RT @timothygirard: Which is certainly possible, but at least one recent RCT examined the data carefully for evidence of heterogeneity of ef…
Which is certainly possible, but at least one recent RCT examined the data carefully for evidence of heterogeneity of effect and found no evidence of such heterogeneity. https://t.co/r4htItyP9R #EDA2018
RT @ARCHDrNguyen: If you refuse healthcare to non English speakers, that’s discrimination: if you refuse to enroll people in research for n…
MIND-USA trial: we should reevaluate routine use of antipsychotics in CAM +ve ICU patients https://t.co/7rTodoSNHC
ICUせん妄に対する精神薬:効果なし Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness. - PubMed - NCBI https://t.co/ZD6JlIx4Hv
RT @ventilacionmeca: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/qW4GkBXsQu
RT @intensivecare_c: せん妄に抗精神病薬は有効か? 急性呼吸不全またはショック+せん妄患者に対する、ハロペリドール vs ziprasidone(非定型抗精神病薬) vs プラセボの比較。 抗精神病薬を使用してもせん妄の期間は短縮しないという結果。 ht…
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/ELsGtAmq5A
RT @ventilacionmeca: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/qW4GkBXsQu
#ICYMI 1, MIND-USA. : The use of haloperidol or ziprasidone, as compared with placebo, in patients with acute respiratory failure or shock and hypoactive or hyperactive delirium in the ICU did not significantly alter the duration of delirium
RT @ventilacionmeca: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/qW4GkBXsQu
The use of haloperidol or ziprasidone, as compared with placebo, in patients with acute respiratory failure or shock and hypoactive or hyperactive delirium in the ICU did not significantly alter the duration of delirium https://t.co/SZ8pBTK0Ah
RT @ventilacionmeca: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/qW4GkBXsQu
RT @ventilacionmeca: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/qW4GkBXsQu
Realmente los resultados de este estudio me generan dudas. Por la baja incidencia de delirium hiperactivo y también por la situación de shock e insuficiencia respiratoria. https://t.co/ZgdqXoEgLk
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/qW4GkBXsQu
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/VNeVqYSG78
RT @intensivecare_c: せん妄に抗精神病薬は有効か? 急性呼吸不全またはショック+せん妄患者に対する、ハロペリドール vs ziprasidone(非定型抗精神病薬) vs プラセボの比較。 抗精神病薬を使用してもせん妄の期間は短縮しないという結果。 ht…
RT @PabloRichly: Parece que es hora de empazar a dejar de usar antipsicóticos en delirium. https://t.co/KNSbjmTgPh
RT @intensivecare_c: せん妄に抗精神病薬は有効か? 急性呼吸不全またはショック+せん妄患者に対する、ハロペリドール vs ziprasidone(非定型抗精神病薬) vs プラセボの比較。 抗精神病薬を使用してもせん妄の期間は短縮しないという結果。 ht…
せん妄に抗精神病薬は有効か? 急性呼吸不全またはショック+せん妄患者に対する、ハロペリドール vs ziprasidone(非定型抗精神病薬) vs プラセボの比較。 抗精神病薬を使用してもせん妄の期間は短縮しないという結果。 https://t.co/CwN3Na2FN8 https://t.co/CwN3Na2FN8
Parece que es hora de empazar a dejar de usar antipsicóticos en delirium. https://t.co/KNSbjmTgPh
RT @ismaelsaid: Desafortunadamente, los antagonistas dopaminérgicos como el haloperidol o la ziprasidona no disminuyen el curso del deliriu…
RT @hmkyale: And how long have we used haloperidol and other anti-psychotics to treat delirium? Too long according to this trial. We need t…
RT @IlindelatorreMD: El uso de haloperidol o ziprasidona, en comparación con el placebo, no alteró significativamente la duración del delir…
RT @accpcritprn: *NEW* MIND-USA Does the use of haloperidol or ziprasidone impact the duration of delirium in critically-ill? #critPRN #AC…
Interested in @A_MacLullich @atula_tweets @SusanShenkin thoughts on #MINDUSA trial. I always thought haloperidol was a symptomatic treatment, why would it modify outcomes in #delirium https://t.co/I20A7uDKtv
RT @IlindelatorreMD: El uso de haloperidol o ziprasidona, en comparación con el placebo, no alteró significativamente la duración del delir…
RT @hmkyale: And how long have we used haloperidol and other anti-psychotics to treat delirium? Too long according to this trial. We need t…
RT @hmkyale: And how long have we used haloperidol and other anti-psychotics to treat delirium? Too long according to this trial. We need t…
RT @hmkyale: And how long have we used haloperidol and other anti-psychotics to treat delirium? Too long according to this trial. We need t…
RT @hmkyale: And how long have we used haloperidol and other anti-psychotics to treat delirium? Too long according to this trial. We need t…
RT @hmkyale: And how long have we used haloperidol and other anti-psychotics to treat delirium? Too long according to this trial. We need t…
RT @hmkyale: And how long have we used haloperidol and other anti-psychotics to treat delirium? Too long according to this trial. We need t…
RT @hmkyale: And how long have we used haloperidol and other anti-psychotics to treat delirium? Too long according to this trial. We need t…
RT @hmkyale: And how long have we used haloperidol and other anti-psychotics to treat delirium? Too long according to this trial. We need t…
RT @hmkyale: And how long have we used haloperidol and other anti-psychotics to treat delirium? Too long according to this trial. We need t…
And how long have we used haloperidol and other anti-psychotics to treat delirium? Too long according to this trial. We need to test all our practices that are under-evidenced! We need a renaissance of research into real-world practices! https://t.co/eurc
RT @IlindelatorreMD: El uso de haloperidol o ziprasidona, en comparación con el placebo, no alteró significativamente la duración del delir…
El uso de haloperidol o ziprasidona, en comparación con el placebo, no alteró significativamente la duración del delirio hipo o hiperactivo | NEJM https://t.co/RQRvvS1TSa
RT @Jacob_Vorstman: Important stuff. Anyone aware of this type of findings for paediatric delirium? https://t.co/GnOOJLq6Id
RT @Tribidibidy: Just in time for the PADIS clinical reasoning series @accp #ACCPCG18 . Antipsychotics still don’t improve delirium. #critP…
RT @KlgiaRespCrit: El uso de haloperidol no se asoció a disminución de la duración del delirium en enfermos críticos #TheEndOfHaloperidol…
RT @virenkaul: Best thing to do for #delirium in ICU? Prevent it by: ☄️Minimizing sedatives 💊regularly reviewing meds on board 🚶🏽♂️Easy…
RT @virenkaul: Best thing to do for #delirium in ICU? Prevent it by: ☄️Minimizing sedatives 💊regularly reviewing meds on board 🚶🏽♂️Easy…
RT @timothygirard: To all of my colleagues who devoted more than a decade of hard work to this clinical trial, I'm incredibly grateful. htt…
RT @KlgiaRespCrit: El uso de haloperidol no se asoció a disminución de la duración del delirium en enfermos críticos #TheEndOfHaloperidol…
El uso de haloperidol no se asoció a disminución de la duración del delirium en enfermos críticos #TheEndOfHaloperidol #TheSlowGoodbyeOfHaloperidol https://t.co/Z1AgHa6ZAD
ICYMI: @NEJM paper on use of antipsychotic medications in ICU delirium - back to the drawing board? Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness https://t.co/Bp7aGIK667
RT @medevidenceblog: Delirium is an epiphenomenon of illness till proved otherwise, and without an elaborated causal mechanism there is no…
First do no harm... https://t.co/4laShit2C6
RT @wilo_estepario: Si el endpoint es días sin delirium y la duración de este, era obvio que no serían mejor que placebo. Muy importante so…
Look again. Bulk of the 566 patients (48%)- 89% had hypoactive delirium and 11% had hyperactive delirium. Most of my problem pts are hyperactive. So I read this as no meds for hypoactive delirium, use non-pharm methods.
RT @DrEl: No effect on length of ICU delirium: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.c…
NEJM continues its negative studies: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness https://t.co/57P2ryoyaQ - No difference from placebo
RT @drafabianalemos: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/sQiSU1iDSV
RT @drafabianalemos: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/sQiSU1iDSV
RT @Epocrates: #Antipsychotics yield disappointing results in #ICU delirium, according to @NEJM https://t.co/TzpvoeHcRs https://t.co/dI4Jq…
#Antipsychotics yield disappointing results in #ICU delirium, according to @NEJM https://t.co/TzpvoeHcRs https://t.co/dI4Jq0oRJQ
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/UkIWugMuNG. Cuando la evidencia te obliga a replantear lo que crees q sabes!!