RT @docterskywalker: Data that’s welcome up on my soapbox: Antipsychotics don’t work for treating ICU delirium. I only consider them when…
RT @timothygirard: To all of my colleagues who devoted more than a decade of hard work to this clinical trial, I'm incredibly grateful. htt…
RT @NEJM: Original Article: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness (MIND-USA) https://t.co/nyMtikjMDC E…
RT @timothygirard: To all of my colleagues who devoted more than a decade of hard work to this clinical trial, I'm incredibly grateful. htt…
Duration of #delirium in the critically ill not affected by #antipsychotics. @NEJM #randomizedtrial #ICU https://t.co/XoeO3msDlH
RT @NEJM: Original Article: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness (MIND-USA) https://t.co/nyMtikjMDC E…
RT @timothygirard: To all of my colleagues who devoted more than a decade of hard work to this clinical trial, I'm incredibly grateful. htt…
RT @virenkaul: Best thing to do for #delirium in ICU? Prevent it by: ☄️Minimizing sedatives 💊regularly reviewing meds on board 🚶🏽♂️Easy…
RT @NEJM: Original Article: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness (MIND-USA) https://t.co/nyMtikjMDC E…
RT @kathy_y_liu: My (limited) experience ->many patients in ITU receive substantial doses of these drugs for delirium. This study shows no…
RT @timothygirard: An article I and others published in @NEJM today has received some attention on Twitter. Of my tweets thus far about the…
RT @kathy_y_liu: My (limited) experience ->many patients in ITU receive substantial doses of these drugs for delirium. This study shows no…
Lack of Benefit for Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/XWfiuUuRGo
RT @timothygirard: To all of my colleagues who devoted more than a decade of hard work to this clinical trial, I'm incredibly grateful. htt…
RT @timothygirard: To all of my colleagues who devoted more than a decade of hard work to this clinical trial, I'm incredibly grateful. htt…
RT @kathy_y_liu: My (limited) experience ->many patients in ITU receive substantial doses of these drugs for delirium. This study shows no…
My (limited) experience ->many patients in ITU receive substantial doses of these drugs for delirium. This study shows no diffs between haloperidol/ziprasidone and placebo in altering duration of delirium/longer term survival.
Evidence-based medicine vs tradition Antipsychotic Drugs Don't Ease ICU Delirium Or Dementia https://t.co/yRhj4HshUE https://t.co/S6SoAH8Z2G @NPRHealth @NEJM #healthcare #delirium #hospital https://t.co/qbF9fUVd3q
@mark_borthwick you seen this ?
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM. A swan song for haloperidol? @v_page https://t.co/Rk76tnEWZA
RT @virenkaul: Best thing to do for #delirium in ICU? Prevent it by: ☄️Minimizing sedatives 💊regularly reviewing meds on board 🚶🏽♂️Easy…
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/r6jtIcl4xW
RT @medevidenceblog: Delirium is an epiphenomenon of illness till proved otherwise, and without an elaborated causal mechanism there is no…
RT @timothygirard: To all of my colleagues who devoted more than a decade of hard work to this clinical trial, I'm incredibly grateful. htt…
ハロペリドール、ziprasidone使用はICUにおける呼吸不全、ショック患者のせん妄罹病期間を短縮しなかった。 Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/OkiO4FEuQg
RT @NakayamaYujiro: 10/22NEJM) ICUのせん妄患者に抗精神病薬vsプラセボのRCT、過去最大サンプル数。結果は有意差なし。理由は1, せん妄はそもそも脳の問題じゃない可能性2, せん妄は色んなメカニズムがある。 Haloperidol and Z…
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness https://t.co/WEQvExngfz
RT @NakayamaYujiro: このような「有意差なし」の論文はかなりの人が誤った解釈をする。 →「有意差なしなのだから、抗精神病薬はせん妄に無効なのだ」 正しくは →「有意差なしなので、本研究からは抗精神病薬がせん妄に有効かどうかは不明」 です。 https://…
RT @NakayamaYujiro: 10/22NEJM) ICUのせん妄患者に抗精神病薬vsプラセボのRCT、過去最大サンプル数。結果は有意差なし。理由は1, せん妄はそもそも脳の問題じゃない可能性2, せん妄は色んなメカニズムがある。 Haloperidol and Z…
RT @NakayamaYujiro: このような「有意差なし」の論文はかなりの人が誤った解釈をする。 →「有意差なしなのだから、抗精神病薬はせん妄に無効なのだ」 正しくは →「有意差なしなので、本研究からは抗精神病薬がせん妄に有効かどうかは不明」 です。 https://…
RT @iceman_ex: Aaaaand it looks like haloperidol and Ziprasidone are done for the treatment of delirium. No difference to placebo in MIND-U…
RT @timothygirard: To all of my colleagues who devoted more than a decade of hard work to this clinical trial, I'm incredibly grateful. htt…
RT @NakayamaYujiro: 10/22NEJM) ICUのせん妄患者に抗精神病薬vsプラセボのRCT、過去最大サンプル数。結果は有意差なし。理由は1, せん妄はそもそも脳の問題じゃない可能性2, せん妄は色んなメカニズムがある。 Haloperidol and Z…
RT @NakayamaYujiro: このような「有意差なし」の論文はかなりの人が誤った解釈をする。 →「有意差なしなのだから、抗精神病薬はせん妄に無効なのだ」 正しくは →「有意差なしなので、本研究からは抗精神病薬がせん妄に有効かどうかは不明」 です。 https://…
RT @NakayamaYujiro: 10/22NEJM) ICUのせん妄患者に抗精神病薬vsプラセボのRCT、過去最大サンプル数。結果は有意差なし。理由は1, せん妄はそもそも脳の問題じゃない可能性2, せん妄は色んなメカニズムがある。 Haloperidol and Z…
RT @NakayamaYujiro: このような「有意差なし」の論文はかなりの人が誤った解釈をする。 →「有意差なしなのだから、抗精神病薬はせん妄に無効なのだ」 正しくは →「有意差なしなので、本研究からは抗精神病薬がせん妄に有効かどうかは不明」 です。 https://…
RT @virenkaul: Best thing to do for #delirium in ICU? Prevent it by: ☄️Minimizing sedatives 💊regularly reviewing meds on board 🚶🏽♂️Easy…
RT @NakayamaYujiro: 10/22NEJM) ICUのせん妄患者に抗精神病薬vsプラセボのRCT、過去最大サンプル数。結果は有意差なし。理由は1, せん妄はそもそも脳の問題じゃない可能性2, せん妄は色んなメカニズムがある。 Haloperidol and Z…
このような「有意差なし」の論文はかなりの人が誤った解釈をする。 →「有意差なしなのだから、抗精神病薬はせん妄に無効なのだ」 正しくは →「有意差なしなので、本研究からは抗精神病薬がせん妄に有効かどうかは不明」 です。
RT @medevidenceblog: Delirium is an epiphenomenon of illness till proved otherwise, and without an elaborated causal mechanism there is no…
RT @NakayamaYujiro: 10/22NEJM) ICUのせん妄患者に抗精神病薬vsプラセボのRCT、過去最大サンプル数。結果は有意差なし。理由は1, せん妄はそもそも脳の問題じゃない可能性2, せん妄は色んなメカニズムがある。 Haloperidol and Z…
Learning from these findings to count more on delirium prevention than treatment!
RT @NEJM: Original Article: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness (MIND-USA) https://t.co/nyMtikjMDC E…
RT @NEJM: Original Article: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness (MIND-USA) https://t.co/nyMtikjMDC E…
RT @jent103: It's an exciting day at the office: Our MIND-USA trial, showing no evidence of benefit (or major harm) from two antipsychotics…
10/22NEJM) ICUのせん妄患者に抗精神病薬vsプラセボのRCT、過去最大サンプル数。結果は有意差なし。理由は1, せん妄はそもそも脳の問題じゃない可能性2, せん妄は色んなメカニズムがある。 Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness https://t.co/bcIdING3o9
RT @NEJM: Original Article: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness (MIND-USA) https://t.co/nyMtikjMDC E…
Do all psychoactive drugs contribute to delirium, just some more than others? Be interesting to know what other drugs patients were having at the same time, and whether they had sepsis… https://t.co/Tjf4ZSLGtk
I’m going to have to read the details but provocative. I get called about these issues even as a Cardiologist at times. Will this change my practice? 🤔
RT @virenkaul: Best thing to do for #delirium in ICU? Prevent it by: ☄️Minimizing sedatives 💊regularly reviewing meds on board 🚶🏽♂️Easy…
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness https://t.co/wHhpbwPu3Q
RT @accpcritprn: *NEW* MIND-USA Does the use of haloperidol or ziprasidone impact the duration of delirium in critically-ill? #critPRN #AC…
RT @virenkaul: Best thing to do for #delirium in ICU? Prevent it by: ☄️Minimizing sedatives 💊regularly reviewing meds on board 🚶🏽♂️Easy…
RT @NEJM: Original Article: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness (MIND-USA) https://t.co/nyMtikjMDC E…
RT @timothygirard: An article I and others published in @NEJM today has received some attention on Twitter. Of my tweets thus far about the…
RT @accpcritprn: *NEW* MIND-USA Does the use of haloperidol or ziprasidone impact the duration of delirium in critically-ill? #critPRN #AC…
RT @NEJM: Original Article: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness (MIND-USA) https://t.co/nyMtikjMDC E…
RT @ATSCritCare: More great work from #LIVES2018, including the MIND-USA trial from @timothygirard and colleagues https://t.co/Yv1XyMboc7
RT @jent103: It's an exciting day at the office: Our MIND-USA trial, showing no evidence of benefit (or major harm) from two antipsychotics…
RT @timothygirard: To all of my colleagues who devoted more than a decade of hard work to this clinical trial, I'm incredibly grateful. htt…
RT @timothygirard: To all of my colleagues who devoted more than a decade of hard work to this clinical trial, I'm incredibly grateful. htt…
RT @medevidenceblog: Delirium is an epiphenomenon of illness till proved otherwise, and without an elaborated causal mechanism there is no…
Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/fmrJ4lDQKZ
RT @virenkaul: Best thing to do for #delirium in ICU? Prevent it by: ☄️Minimizing sedatives 💊regularly reviewing meds on board 🚶🏽♂️Easy…
RT @medevidenceblog: Delirium is an epiphenomenon of illness till proved otherwise, and without an elaborated causal mechanism there is no…
RT @timothygirard: An article I and others published in @NEJM today has received some attention on Twitter. Of my tweets thus far about the…
RT @medevidenceblog: Delirium is an epiphenomenon of illness till proved otherwise, and without an elaborated causal mechanism there is no…
RT @virenkaul: Best thing to do for #delirium in ICU? Prevent it by: ☄️Minimizing sedatives 💊regularly reviewing meds on board 🚶🏽♂️Easy…
https://t.co/7AlsNEOPRH ICU入室患者のせん妄に対して、抗精神薬の影響を調べたRCT ハロペリドール(最大用量20mg /日)、ジプラシドン(最大用量40mg /日)、プラセボを投与する3群に割付。結果は、14日間の間でせん妄がなかった期間は7.9day vs.8.7day vs.8.5dayで有意差はなかった #当麻_鎮痛鎮静
RT @timothygirard: An article I and others published in @NEJM today has received some attention on Twitter. Of my tweets thus far about the…
RT @medevidenceblog: Delirium is an epiphenomenon of illness till proved otherwise, and without an elaborated causal mechanism there is no…
RT @medevidenceblog: Delirium is an epiphenomenon of illness till proved otherwise, and without an elaborated causal mechanism there is no…
Delirium is an epiphenomenon of illness till proved otherwise, and without an elaborated causal mechanism there is no reason to expect effect of: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/nv1LTaDWVP
RT @virenkaul: Best thing to do for #delirium in ICU? Prevent it by: ☄️Minimizing sedatives 💊regularly reviewing meds on board 🚶🏽♂️Easy…
RT @virenkaul: Best thing to do for #delirium in ICU? Prevent it by: ☄️Minimizing sedatives 💊regularly reviewing meds on board 🚶🏽♂️Easy…
Lovers of ziprasidone (me), it's been debunked. Great work, including by my mentor- Babar Khan, who's still not on Twitter. On my reading list for tomorrow... https://t.co/s6lyApXDQF … @IUPCCM @YalePCCSM
Haldol has no effect on the duration of delirium for the treatment of critical illness. https://t.co/wjrZecUt0J
RT @DrOChaudhary: Precedex for everyone! No, but seriously this may be a paradigm shift in delirium management. Time to implement all those…
RT @virenkaul: Best thing to do for #delirium in ICU? Prevent it by: ☄️Minimizing sedatives 💊regularly reviewing meds on board 🚶🏽♂️Easy…
RT @virenkaul: Best thing to do for #delirium in ICU? Prevent it by: ☄️Minimizing sedatives 💊regularly reviewing meds on board 🚶🏽♂️Easy…
RT @virenkaul: Best thing to do for #delirium in ICU? Prevent it by: ☄️Minimizing sedatives 💊regularly reviewing meds on board 🚶🏽♂️Easy…
RT @timothygirard: To all of my colleagues who devoted more than a decade of hard work to this clinical trial, I'm incredibly grateful. htt…
RT @SESanchezMD: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness | NEJM https://t.co/u777UhUOOB
Clinician use of antipsychotics for hypoactive delirium likely stems from our NEED to do something for a patient on a given ICU day. I believe the aim of most is to improve on ventilator free days and that question still remains unanswered. I guess #LessIs
RT @timothygirard: An article I and others published in @NEJM today has received some attention on Twitter. Of my tweets thus far about the…
RT @timothygirard: To all of my colleagues who devoted more than a decade of hard work to this clinical trial, I'm incredibly grateful. htt…
RT @ADAlthousePhD: Massive congratulations to @PittCCM's @timothygirard for publishing the MIND-USA trial in @NEJM. At a glance looked lik…
RT @timothygirard: An article I and others published in @NEJM today has received some attention on Twitter. Of my tweets thus far about the…
RT @ATSCritCare: More great work from #LIVES2018, including the MIND-USA trial from @timothygirard and colleagues https://t.co/Yv1XyMboc7
RT @virenkaul: Best thing to do for #delirium in ICU? Prevent it by: ☄️Minimizing sedatives 💊regularly reviewing meds on board 🚶🏽♂️Easy…
Or ICU delirium as it were...
RT @timothygirard: To all of my colleagues who devoted more than a decade of hard work to this clinical trial, I'm incredibly grateful. htt…
RT @jent103: It's an exciting day at the office: Our MIND-USA trial, showing no evidence of benefit (or major harm) from two antipsychotics…
RT @timothygirard: An article I and others published in @NEJM today has received some attention on Twitter. Of my tweets thus far about the…
RT @NEJM: Original Article: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness (MIND-USA) https://t.co/nyMtikjMDC E…
RT @NEJM: Original Article: Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness (MIND-USA) https://t.co/nyMtikjMDC E…