RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
This is so cool.
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @DrYukselUrun: 🔶Liver metastases create a systemic immune desert in preclinical models! 🔶Liver-directed ☢️ eliminates immunosuppressive…
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @Johanna_A_Joyce: Fascinating new #TumorMicroenvironment study in @NatureMedicine Liver metastases siphon activated CD8+ T cells from th…
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @Johanna_A_Joyce: Fascinating new #TumorMicroenvironment study in @NatureMedicine Liver metastases siphon activated CD8+ T cells from th…
RT @Johanna_A_Joyce: Fascinating new #TumorMicroenvironment study in @NatureMedicine Liver metastases siphon activated CD8+ T cells from th…
RT @Johanna_A_Joyce: Fascinating new #TumorMicroenvironment study in @NatureMedicine Liver metastases siphon activated CD8+ T cells from th…
RT @Johanna_A_Joyce: Fascinating new #TumorMicroenvironment study in @NatureMedicine Liver metastases siphon activated CD8+ T cells from th…
RT @DrYukselUrun: 🔶Liver metastases create a systemic immune desert in preclinical models! 🔶Liver-directed ☢️ eliminates immunosuppressive…
Wow this is cool! #radonc #Immunotherapy #liver
RT @DrYukselUrun: 🔶Liver metastases create a systemic immune desert in preclinical models! 🔶Liver-directed ☢️ eliminates immunosuppressive…
RT @MustafaRaoofMD: Really nice pre-clinical work suggesting liver directed therapy for liver mets across cancer types may improve immunoth…
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
Really nice pre-clinical work suggesting liver directed therapy for liver mets across cancer types may improve immunotherapy efficacy
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @DrYukselUrun: 🔶Liver metastases create a systemic immune desert in preclinical models! 🔶Liver-directed ☢️ eliminates immunosuppressive…
This is beyond brilliant. Such exciting progress in the cancer pre-clinical cancer world with an increasing amount of translational implementation. Hoping neurodegenerative disease are soon to follow.
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
Hmm, one piece in the puzzle explaining what we have been seeing for years in the clinic #bcsm
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
Nature med、Weiping Zouのグループから。肝転移が免疫療法抵抗性となる機序。肝腫瘍環境のマクロファージが、CD8+T細胞のアポトーシスを誘導し、これが全身に影響。 別グループからも肝転移で誘導されたTreg/MDSCが…という話もあったし、肝転移と免疫の関係、真実味感じる。 https://t.co/bjg5T6NhiE
肝臓の免疫担当細胞の供給源ってどこだっけ?“liver metastases create a systemic immune desert in preclinical models”
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @DrYukselUrun: 🔶Liver metastases create a systemic immune desert in preclinical models! 🔶Liver-directed ☢️ eliminates immunosuppressive…
RT @angelbeverido: Las metástasis hepáticas disminuyen la eficacia de la inmunoterapia a través de la eliminación de células T mediada por…
RT @DrYukselUrun: 🔶Liver metastases create a systemic immune desert in preclinical models! 🔶Liver-directed ☢️ eliminates immunosuppressive…
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @DrYukselUrun: 🔶Liver metastases create a systemic immune desert in preclinical models! 🔶Liver-directed ☢️ eliminates immunosuppressive…
RT @DrYukselUrun: 🔶Liver metastases create a systemic immune desert in preclinical models! 🔶Liver-directed ☢️ eliminates immunosuppressive…
RT @DrYukselUrun: 🔶Liver metastases create a systemic immune desert in preclinical models! 🔶Liver-directed ☢️ eliminates immunosuppressive…
RT @Johanna_A_Joyce: Fascinating new #TumorMicroenvironment study in @NatureMedicine Liver metastases siphon activated CD8+ T cells from th…
RT @Johanna_A_Joyce: Fascinating new #TumorMicroenvironment study in @NatureMedicine Liver metastases siphon activated CD8+ T cells from th…
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @Johanna_A_Joyce: Fascinating new #TumorMicroenvironment study in @NatureMedicine Liver metastases siphon activated CD8+ T cells from th…
Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination | Nature Medicine https://t.co/wdrsCaeCCQ
🔶Liver metastases create a systemic immune desert in preclinical models! 🔶Liver-directed ☢️ eliminates immunosuppressive hepatic macrophages, ↗️ hepatic T cell survival and ↘️ hepatic siphoning of T cells. @NatureMedicine @OncoAlert @sitcancer https://t.
Read the study: https://t.co/rQg5E3OvXn
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
Fantastic study!! Congratulations to the authors! #Science #CancerResearch
RT @VilmaPBarcia: 🔆 Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination. @NatureMedicine @OncoAlert
🔆 Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination. @NatureMedicine @OncoAlert
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @Johanna_A_Joyce: Fascinating new #TumorMicroenvironment study in @NatureMedicine Liver metastases siphon activated CD8+ T cells from th…
Las metástasis hepáticas disminuyen la eficacia de la inmunoterapia a través de la eliminación de células T mediada por macrófagos. Yu, J., Green, M.D., Li, S. et al. Nature Medicine (2021). https://t.co/kezp7VMGID https://t.co/GPjXQK0mB6
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
Fascinating new #TumorMicroenvironment study in @NatureMedicine Liver metastases siphon activated CD8+ T cells from the circulation. As a result, liver mets create a systemic immune desert in preclinical models & in patients, which can be alleviated by
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
RT @NatureMedicine: Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but th…
Another report which shows host macrophages working in favour of tumor by directing CD8 T cell apoptosis. Very interesting read. #tcells #Immunotherapy #tumorimmunology
Start the new year off with this cool paper from Weiping Zou, Michael Green, Jiali Yu and colleagues @umichmedicine now live @NatureMedicine! If you're interested in #livermetastasis, #immunotherapy, #liver immuno or #macrophages, you'll want to read this
Liver metastases reduce #immunotherapy efficacy through hepatic siphoning of circulating activated CD8+ #Tcells, but therapeutic benefit can be improved by combining with liver-directed #radiotherapy #metastasis #macrophages @UMichSurgery @umichmedicine ht