Las pseudoterapias mercantiles en ámbitos de supuesta medicina científica dañan aún más la credibilidad de la profesión que cuando se practican fuera del sistema.
RT @rafabravo: La administración temprana de vitamina D3 enteral en dosis altas no proporcionó una ventaja sobre el placebo con respecto a…
RT @rafabravo: La administración temprana de vitamina D3 enteral en dosis altas no proporcionó una ventaja sobre el placebo con respecto a…
RT @rafabravo: La administración temprana de vitamina D3 enteral en dosis altas no proporcionó una ventaja sobre el placebo con respecto a…
RT @rafabravo: La administración temprana de vitamina D3 enteral en dosis altas no proporcionó una ventaja sobre el placebo con respecto a…
RT @rafabravo: La administración temprana de vitamina D3 enteral en dosis altas no proporcionó una ventaja sobre el placebo con respecto a…
La administración temprana de vitamina D3 enteral en dosis altas no proporcionó una ventaja sobre el placebo con respecto a la mortalidad a los 90 días u otros resultados no fatales entre los pacientes críticamente enfermos con deficiencia de vitamina D ht
@Rober1430 @fenris1234 @vbaosv Ya se sabe que no aporta en otros pacientes y seguro que lo estará haciendo alguien ya en #COVID19. https://t.co/RF4uVWNr7K
6\ Uit een recente grote studie bij IC patiënten blijkt juist dat vitamine D GEEN ENKEL positief effect heeft in vergelijking met placebo (als er al een verschil was dan had vitamine D juist hogere kans op overlijden): https://t.co/rLduVIlIDq
@Yolanda_radio Esto tiene de “nuevo” lo que yo de rubio 😅 Este trabajo está muy bien y se observa que suplementar no aporta nada en pacientes críticos no #COVID19 Supongo que ya se estará haciendo en algún sitio algo parecido. https://t.co/RF4uVWNr7K
@gshotwell @__ice9 Although, not always. Could it be specific to Covid-19 patients? https://t.co/pxiu703c19
In critically ill, Vitamin D deficient patients with 90-day end point mortality expectancy, giving an initial high dose of Vitamin D was not advantageous in their mortality. https://t.co/v2ka5WPEVo #FMPH40Fall20
Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients | NEJM https://t.co/WaJMh06uSf
RT @ChrisCarrollMD: Dr. Adit Ginde presenting the VIOLET Trial of #VitaminD and #ARDS showing the Vitamin D did not improve outcomes in thi…
Dr. Adit Ginde presenting the VIOLET Trial of #VitaminD and #ARDS showing the Vitamin D did not improve outcomes in this population. #CHEST202 https://t.co/Snbsn2SDt5 https://t.co/GDroXwbSYF
RT @CHESTCritCare: Here are some references if you want to read on the topic prior to attending this live session that promises to be fanta…
RT @CHESTCritCare: Here are some references if you want to read on the topic prior to attending this live session that promises to be fanta…
Here are some references if you want to read on the topic prior to attending this live session that promises to be fantastic! https://t.co/525pUBs2qU https://t.co/qz9pQD9Tqg https://t.co/CuZmR0DrTT https://t.co/2a3FKfrsq6 https://t.co/HEHH5S4ijG
RT @CHESTCritCare: In the VIOLET trial, patients who were Vit-D deficient and were at high risk for death were randomized to early vitD3 su…
This and much more comming your way! Register now for @accpchest #CHEST2020. Always happy to help #DrSarangPatil #CHESTSoMe
In the VIOLET trial, patients who were Vit-D deficient and were at high risk for death were randomized to early vitD3 supplementation versus placebo. VitD3 administration didn't provide advantage over placebo with respect to 90 day mortality. https://t.c
@robertwiblin More apropos of your current concern: Vit deficiency looked like a bad prognostic trend in ICU patients, very clear observational signal. Randomization -> no effect. https://t.co/ffuFiKFiu7 There's a billion of these trials.
@gshotwell @CaulfieldTim I'd love 50% odds on Vitamin D. https://t.co/3lJ8e75OVw
Natalie Sibold, APPE student, reviewing the VIOLET trial today! Working to determine if vitamin D3 can really 'D'efend in the ICU if administered early enough to patients with at least one risk factor for ICU mortality. https://t.co/6FlnNGAfnK
@me_sheer_ @peteragro @DaniOliver Hi, vitamin D doesn't do anything, even in vitamin D deficient patients. https://t.co/IxT7xJkbha
Early High-Dose #Vitamin #D3 for Critically Ill, Vitamin D–Deficient Patients | rt @NEJM https://t.co/gTFjrAwoiz
@ETM_Kaipiainen @JuhaniKnuuti @TeroVaine D-vitamiini ei myöskään näyttänyt suurenakaan annoksena tuottavan hyötyä kriittisesti sairaille potilaille joilla oli nimenomaan D-vitamiinin puutos: https://t.co/x9xCpXME2c Luulisi että jos olisi joku ratkaiseva
これがそれ。#COVID19 だけでなく、非特異的な効果は有るのかもねな https://t.co/diIRzOtDsw
RT @Alzhacker: 重症患者における高用量ビタミンD(ビタミンD3、540,000 IU!の単回投与)の役割を評価するランダム化比較試験では、高用量ビタミンDからの利益は実証できなかった。 https://t.co/j1paVtuQb8
RT @RD_Catherine: #VitaminD in #ICU patients. Yes, it's often low. Yes, it's needed to produce LL-37 from the only cathelicidin we humans m…
RT @Alzhacker: 重症患者における高用量ビタミンD(ビタミンD3、540,000 IU!の単回投与)の役割を評価するランダム化比較試験では、高用量ビタミンDからの利益は実証できなかった。 https://t.co/j1paVtuQb8
RT @Alzhacker: 重症患者における高用量ビタミンD(ビタミンD3、540,000 IU!の単回投与)の役割を評価するランダム化比較試験では、高用量ビタミンDからの利益は実証できなかった。 https://t.co/j1paVtuQb8
RT @Alzhacker: 重症患者における高用量ビタミンD(ビタミンD3、540,000 IU!の単回投与)の役割を評価するランダム化比較試験では、高用量ビタミンDからの利益は実証できなかった。 https://t.co/j1paVtuQb8
他のウイルスか何かの研究でビタミンD3を投与するよりも日光浴の方が有効だった、みたいのがあった様な気がするのですがどの論文だったか忘れた・・・ 予防効果はあったとしても一度重症化の勢いが付いてしまうと、IL-6に強引にブレーキをかけたり他の副作用もある方法などで止めないと難しいのかも。
RT @Alzhacker: 重症患者における高用量ビタミンD(ビタミンD3、540,000 IU!の単回投与)の役割を評価するランダム化比較試験では、高用量ビタミンDからの利益は実証できなかった。 https://t.co/j1paVtuQb8
RT @Alzhacker: 重症患者における高用量ビタミンD(ビタミンD3、540,000 IU!の単回投与)の役割を評価するランダム化比較試験では、高用量ビタミンDからの利益は実証できなかった。 https://t.co/j1paVtuQb8
RT @Alzhacker: 重症患者における高用量ビタミンD(ビタミンD3、540,000 IU!の単回投与)の役割を評価するランダム化比較試験では、高用量ビタミンDからの利益は実証できなかった。 https://t.co/j1paVtuQb8
RT @Alzhacker: 重症患者における高用量ビタミンD(ビタミンD3、540,000 IU!の単回投与)の役割を評価するランダム化比較試験では、高用量ビタミンDからの利益は実証できなかった。 https://t.co/j1paVtuQb8
RT @Alzhacker: 重症患者における高用量ビタミンD(ビタミンD3、540,000 IU!の単回投与)の役割を評価するランダム化比較試験では、高用量ビタミンDからの利益は実証できなかった。 https://t.co/j1paVtuQb8
重症患者における高用量ビタミンD(ビタミンD3、540,000 IU!の単回投与)の役割を評価するランダム化比較試験では、高用量ビタミンDからの利益は実証できなかった。 https://t.co/j1paVtuQb8
RT @RD_Catherine: #VitaminD in #ICU patients. Yes, it's often low. Yes, it's needed to produce LL-37 from the only cathelicidin we humans m…
RT @RD_Catherine: #VitaminD in #ICU patients. Yes, it's often low. Yes, it's needed to produce LL-37 from the only cathelicidin we humans m…
RT @RD_Catherine: #VitaminD in #ICU patients. Yes, it's often low. Yes, it's needed to produce LL-37 from the only cathelicidin we humans m…
Another good Vitamind D study on critically ill- thanks Catherine.
RT @RD_Catherine: #VitaminD in #ICU patients. Yes, it's often low. Yes, it's needed to produce LL-37 from the only cathelicidin we humans m…
#VitaminD in #ICU patients. Yes, it's often low. Yes, it's needed to produce LL-37 from the only cathelicidin we humans make. No, single high dose supplements of no proven benefit in reducing ICU mortality #VITdAL: https://t.co/MlCjXtNmor and #VIOLET: htt
Recent RCT: https://t.co/9DvRCe5V2z "Early administration of high-dose enteral vitamin D3 did not provide an advantage over placebo with respect to 90-day mortality or other, nonfatal outcomes among critically ill, vitamin D–deficient patients."
@Eileen89423202 El link que nos envías, no pertenece a una revista médica científica, la recopilación es del 2016 me parece. Adjuntamos un artículo de 26/12/2019 del NEJM https://t.co/wUj8Or57NA
RT @saniom1: Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients | NEJM https://t.co/JDCnva0RAt
No
Yes, so I have thought a lot about it and submitted a letter to the editor - no 1 problem: a one time megadose in a very vulnerable moment may not be the best approach for a substance with a half life of 2 weeks and a prim endpoint of 90-day mortality
@79ka2011 Ummm... https://t.co/lIUP5TPVOL
RT @epocrates: High-dose vitamin D fails to show benefit in critically ill patients via @NEJM https://t.co/HVWb5nbYNF https://t.co/ykAg570…
【NEJM 2019.12:RCT】ビタミンD欠乏しているICU患者に対する大量ビタミンD3経腸投与は治療効果に影響なし。この研究が行われた背景を知らないので、この研究のすごさがイマイチわかりません。 https://t.co/Qqc0KEI1u6
RT @OSUEMEdu: Congrats to our own Jeff Caterino and Tom Terndrup as well as Matt Exline @pulmmatt Josh Englert @joshenglert_md and #OSUWexM…
High-dose vitamin D fails to show benefit in critically ill patients via @NEJM https://t.co/HVWb5nbYNF https://t.co/ykAg570w6y
Congrats to our own Jeff Caterino and Tom Terndrup as well as Matt Exline @pulmmatt Josh Englert @joshenglert_md and #OSUWexMed colleagues for their work on new @NEJM study! #VIOLET #PETALS #VitaminD https://t.co/14QdrIK24F
RT @sreeja_natesan: Check out the incredible work being done .@dukeemergency!! Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–De…
Check out the incredible work being done .@dukeemergency!! Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients | NEJM https://t.co/J4bR3Cq5mF
Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients | NEJM https://t.co/ET70mAKh2q
RT @acepccmsection: Also from PETAL, VIOLET with lead author Adit Ginde @CUEmergency found no benefit of vitamin D3 supplementation in crit…
Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients | NEJM https://t.co/1LGaEXBJFI
RT @ErnMedBlog: Welchen Vorteil hat die Supplementation von hochdosiertem Vitamin D bei kritisch Kranken mit Vitamin-D-Mangel? https://t.co…
RT @vic_pallares: Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients | NEJM https://t.co/pTWniK8kIG @Medtorek @an…
RT @mencardio: Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients | NEJM https://t.co/ne3pza1Tc8
Ölüm riski yüksek, D vitamini eksikliği olan yaşlı hastalarda erken dönemde D vitamini tedavisi başlamanın yararı var mı? NEJM'de yayınlanan çalışma, HAYIR diyor. https://t.co/SWpKb6a5fw #FOAMed https://t.co/Lj68LdS6aJ
Early administration of high-dose enteral vitamin D3 did not provide an advantage over placebo with respect to 90-day mortality or other, nonfatal outcomes among critically ill, vitamin D–deficient patients. https://t.co/DqvOpqkJ7T
4⃣ Vit D in the ICU? The #VIOLET 🌸study in @NEJM evaluated high dose (❗️540,000 IU❗️) PO #VitD repletion in ICU pts. While the #VITdAL-ICU study maybe showed benefit, this one showed no difference. Stop checking #VitD in the ICU! https://t.co/4HCggNc7lE
Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients | NEJM https://t.co/ne3pza1Tc8
RT @vic_pallares: Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients | NEJM https://t.co/pTWniK8kIG @Medtorek @an…
RT @vic_pallares: Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients | NEJM https://t.co/pTWniK8kIG @Medtorek @an…
RT @MoAtta007: https://t.co/ZeEqRbGJxF another nail to the coffin! For those who love giving vitamin D. This is about number 4 trial this y…
RT @NEJM: This randomized, placebo-controlled trial examined the potential benefits of vitamin D3 supplementation in acute critical illness…
RT @acepccmsection: Also from PETAL, VIOLET with lead author Adit Ginde @CUEmergency found no benefit of vitamin D3 supplementation in crit…
Also from PETAL, VIOLET with lead author Adit Ginde @CUEmergency found no benefit of vitamin D3 supplementation in critically-ill deficient patients. 11/ https://t.co/ZC6sH8qxXq
RT @ErnMedBlog: Welchen Vorteil hat die Supplementation von hochdosiertem Vitamin D bei kritisch Kranken mit Vitamin-D-Mangel? https://t.co…
Welchen Vorteil hat die Supplementation von hochdosiertem Vitamin D bei kritisch Kranken mit Vitamin-D-Mangel? https://t.co/Um8SzwaAh4 #VitaminD
NEJMから急性期疾患時にビタミンD欠乏がある場合に活性化ビタミンD3の早期大量投与が有効か否かの論文。結果は予後改善に寄与しない。投与量は540000IUと日本で使うアルファカルシドール1μg製剤13500個に相当。https://t.co/hWBrvPIW5i
RT @NHLBI_LUNGDir: #NHLBI PETAL network’s VIOLET trial did not show a benefit of high dose vitamin D given early to critically ill patients…
RT @NHLBI_LUNGDir: #NHLBI PETAL network’s VIOLET trial did not show a benefit of high dose vitamin D given early to critically ill patients…
RT @NHLBI_LUNGDir: #NHLBI PETAL network’s VIOLET trial did not show a benefit of high dose vitamin D given early to critically ill patients…
RT @NHLBI_LUNGDir: #NHLBI PETAL network’s VIOLET trial did not show a benefit of high dose vitamin D given early to critically ill patients…
RT @osteoporosisNI: Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients | NEJM https://t.co/rP3CoA0zS6 Mega dose…
RT @neil_orford: NHLBI PETAL https://t.co/wFHA3XZuS8 Network report early administration of 540,000 IU vitamin D3 in 1360 adult ICU patient…
En el paciente mayor frágil, conocemos que lo más fisiólogico es administrar la hormona D diariamente a pacientes deficientes y que las megadosis no aportan beneficio o aumentan la motalidad
Vitamin D use has been grossly oversold and at these high doses may be dangerous. remember we need to measure bioavailable D. Dark skinned persons have much lower values of 25(OH)vitamin D
RT @neil_orford: NHLBI PETAL https://t.co/wFHA3XZuS8 Network report early administration of 540,000 IU vitamin D3 in 1360 adult ICU patient…
RT @neil_orford: NHLBI PETAL https://t.co/wFHA3XZuS8 Network report early administration of 540,000 IU vitamin D3 in 1360 adult ICU patient…
#NHLBI PETAL network’s VIOLET trial did not show a benefit of high dose vitamin D given early to critically ill patients with vitamin D deficiency. #Lung50 https://t.co/T4XclchXG3
RT @osteoporosisNI: Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients | NEJM https://t.co/rP3CoA0zS6 Mega dose…
Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients | NEJM https://t.co/WN5uO3nlhX
RT @osteoporosisNI: Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients | NEJM https://t.co/rP3CoA0zS6 Mega dose…
Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients | NEJM https://t.co/rP3CoA0zS6 Mega dose #vitD doesn’t improve survival in vitD deficient ICU patients. #vitaminD effects so complex. Have never agreed with megadose/sledgehammer
RT @neil_orford: NHLBI PETAL https://t.co/wFHA3XZuS8 Network report early administration of 540,000 IU vitamin D3 in 1360 adult ICU patient…
RT @NEJM: This randomized, placebo-controlled trial examined the potential benefits of vitamin D3 supplementation in acute critical illness…
RT @neil_orford: NHLBI PETAL https://t.co/wFHA3XZuS8 Network report early administration of 540,000 IU vitamin D3 in 1360 adult ICU patient…
NHLBI PETAL https://t.co/wFHA3XZuS8 Network report early administration of 540,000 IU vitamin D3 in 1360 adult ICU patients at high risk of death, did not result in reduction in mortality. Waiting for VITDALIZE n=240 https://t.co/7GIs8fvsrd
RT @ErinMichos: Another negative #VitaminD #RCT: "Early administration of high-dose vitamin D3 did not provide an advantage over placebo w…
Early High-Dose Vitamin D3 for Critically Ill, Vitamin D–Deficient Patients @NEJM https://t.co/cvjTucDV0h