RT @Aiims1742: #MarchMadness continues Back 2 back papers in @NatureMedicine on combination MEK/ERK + autophagy inhibition in #PancreaticCa…
RT @keisuke4713: mitogen-activated protein kinase(MAPK)→癌 https://t.co/SmjGOqnc6V MAPK:細胞外signal→細胞内応答へ切り替えで重要な架け橋 膵臓癌の治療としてのERKとautophagy…
mitogen-activated protein kinase(MAPK)→癌 https://t.co/SmjGOqnc6V MAPK:細胞外signal→細胞内応答へ切り替えで重要な架け橋 膵臓癌の治療としてのERKとautophagy阻害 https://t.co/VzRM1q6bLd 合成β-nitrostyrene誘導体はROS→MEK/ERK経路→乳癌細胞死とautophagy誘導 https://t.co/y6JxlNZtDh https://t.co/D499lco5zP
RT @TumorBoardTues: 8/12 #TumorBoardTuesday Thursday Case🎀 ✅KRAS G12R associated with ⬆️ autophagic flux Led to combo therapy with tram…
RT @TumorBoardTues: 8/12 #TumorBoardTuesday Thursday Case🎀 ✅KRAS G12R associated with ⬆️ autophagic flux Led to combo therapy with tram…
8/12 #TumorBoardTuesday Thursday Case🎀 ✅KRAS G12R associated with ⬆️ autophagic flux Led to combo therapy with trametinib (MEKi) + hydroxychloroquine (HCQ) (inhibits autophagy). Pt response for 4 months, but then--disease progression😥 https://t.co/Ww
RT @cancercommons: @TumorBoardTues @ShaalanBeg @MPishvaian @ConanKinsey @LolaRahib @DavendraSohal @dkfchang @derlabunc 13/21 ERK1/2 can inh…
RT @cancercommons: @TumorBoardTues @ShaalanBeg @MPishvaian @ConanKinsey @LolaRahib @DavendraSohal @dkfchang @derlabunc 13/21 ERK1/2 can inh…
RT @cancercommons: @TumorBoardTues @ShaalanBeg @MPishvaian @ConanKinsey @LolaRahib @DavendraSohal @dkfchang @derlabunc 13/21 ERK1/2 can inh…
RT @cancercommons: @TumorBoardTues @ShaalanBeg @MPishvaian @ConanKinsey @LolaRahib @DavendraSohal @dkfchang @derlabunc 13/21 ERK1/2 can inh…
RT @cancercommons: @TumorBoardTues @ShaalanBeg @MPishvaian @ConanKinsey @LolaRahib @DavendraSohal @dkfchang @derlabunc 13/21 ERK1/2 can inh…
@TumorBoardTues @ShaalanBeg @MPishvaian @ConanKinsey @LolaRahib @DavendraSohal @dkfchang @derlabunc 13/21 ERK1/2 can inhibit 🚫LKB1 ▶️ through serine phosphorylation (pS428) 🔗🔗🔗⏭️⏭️ @bryant_kl 👩🔬et al 👉 ERK inhibition impairs metabolic processes (glycolysi
The authors of "Combination of ERK and autophagy inhibition as a t…" (https://t.co/L4QOSPY5Gh) included RRIDs in their paper! We appreciate the author's support of reproducibility. #methodsmatter #reproducibility
RT @bryant_kl: Thanks @PanCAN for the opportunity to share our work with the #PanCANscientificfamily and for funding this and other deservi…
RT @bryant_kl: Thanks @PanCAN for the opportunity to share our work with the #PanCANscientificfamily and for funding this and other deservi…
RT @bryant_kl: Thanks @PanCAN for the opportunity to share our work with the #PanCANscientificfamily and for funding this and other deservi…
Thanks @PanCAN for the opportunity to share our work with the #PanCANscientificfamily and for funding this and other deserving #pancreatic #metabolism studies. Check out the full story here: https://t.co/MhKMtTAsW8
@StanfordMed @OHSUKnight @columbiacancer @MayoClinic Kirsten Bryant @derlabunc (#AACRPanCa19) Autophagy inhibition with HCQ along with MEK/ERKi as a way to target PDAC. Dose of HCQ matters! New inhibitors and combos on the way. https://t.co/rJnonH8ISN http
メモ。抗マラリア薬のクロロキンがオートファゴソーム形成阻害するのを利用して、KRAS変異膵癌にERK阻害剤(オートファジー依存性を高める)とクロロキンを併用すると相乗効果で腫瘍が縮小するという話。※動物ゼノグラフト実験 /Nat Med https://t.co/Lw1tProM3Z
RT @NeliMUlrich: Two top reads in @NatureMedicine! Lab breakthrough by Martin McMahon, Conan Kinsey and colleagues for new #pancreascancer…
RT @NatureMedicine: New research by Martin McMahon @UUtah & Channing Der @UNC_Lineberger describe co-inhibition of RAF-MEK-ERK signaling an…
RT @NatureMedicine: New research by Martin McMahon @UUtah & Channing Der @UNC_Lineberger describe co-inhibition of RAF-MEK-ERK signaling an…
RT @NatureMedicine: New research by Martin McMahon @UUtah & Channing Der @UNC_Lineberger describe co-inhibition of RAF-MEK-ERK signaling an…
See our recommendation of Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer https://t.co/P2UINO6z3W
New perspectives #PancreaticCancer
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer @nature @NatureMedicine https://t.co/27Xlbf9UNc
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer $ARWR $DRNA $ALNY $ABUS $RXII $SLN @OliXPharmaceut1 #siRNA #RNAi @RNAi_papers @killinfectdhost @mfosborn @bmcruzgod @LauraSepplore https://t.co/4ApEfNV4xo https://t
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer | Nature Medicine https://t.co/FwhBYuRpBu
RT @Aiims1742: #MarchMadness continues Back 2 back papers in @NatureMedicine on combination MEK/ERK + autophagy inhibition in #PancreaticCa…
RT @Aiims1742: #MarchMadness continues Back 2 back papers in @NatureMedicine on combination MEK/ERK + autophagy inhibition in #PancreaticCa…
RT @bryant_kl: Thanks @CD_AACR for highlighting our #PancreaticCancer study in @NatureMedicine. Check out the full story here: https://t.co…
RT @Aiims1742: #MarchMadness continues Back 2 back papers in @NatureMedicine on combination MEK/ERK + autophagy inhibition in #PancreaticCa…
RT @bryant_kl: Thanks @CD_AACR for highlighting our #PancreaticCancer study in @NatureMedicine. Check out the full story here: https://t.co…
RT @bryant_kl: Thanks @CD_AACR for highlighting our #PancreaticCancer study in @NatureMedicine. Check out the full story here: https://t.co…
RT @bryant_kl: Thanks @CD_AACR for highlighting our #PancreaticCancer study in @NatureMedicine. Check out the full story here: https://t.co…
RT @bryant_kl: Thanks @CD_AACR for highlighting our #PancreaticCancer study in @NatureMedicine. Check out the full story here: https://t.co…
RT @bryant_kl: Thanks @CD_AACR for highlighting our #PancreaticCancer study in @NatureMedicine. Check out the full story here: https://t.co…
RT @bryant_kl: Thanks @CD_AACR for highlighting our #PancreaticCancer study in @NatureMedicine. Check out the full story here: https://t.co…
RT @bryant_kl: Thanks @CD_AACR for highlighting our #PancreaticCancer study in @NatureMedicine. Check out the full story here: https://t.co…
RT @bryant_kl: Thanks @CD_AACR for highlighting our #PancreaticCancer study in @NatureMedicine. Check out the full story here: https://t.co…
Thanks @CD_AACR for highlighting our #PancreaticCancer study in @NatureMedicine. Check out the full story here: https://t.co/LQPbixccmV
RT @NatureMedicine: New research by Martin McMahon @UUtah & Channing Der @UNC_Lineberger describe co-inhibition of RAF-MEK-ERK signaling an…
RT @AndyBiotech: Two new papers in @NatureMedicine on MEK/ERKi + autophagy inhibition combination approach to treat #PancreaticCancer http…
From last week in @NatureMedicine: @UNC_Lineberger scientists show that, to their surprise, suppression of KRAS increased autophagic flux, as did pharmacological inhibition of its effector ERK MAPK. https://t.co/c5F0Q4DQRV @bryant_kl https://t.co/SAfJRKDWp
RT @NatureMedicine: New research by Martin McMahon @UUtah & Channing Der @UNC_Lineberger describe co-inhibition of RAF-MEK-ERK signaling an…
RT @Aiims1742: #MarchMadness continues Back 2 back papers in @NatureMedicine on combination MEK/ERK + autophagy inhibition in #PancreaticCa…
Breakthrough !?? A series of 3 papers now showing real promise for Pancreatic Cancer Treatment. Double whammy against Mek-Erk and Autophagy kills Cancer Cells.
RT @NatureMedicine: New research by Martin McMahon @UUtah & Channing Der @UNC_Lineberger describe co-inhibition of RAF-MEK-ERK signaling an…
RT @Aiims1742: #MarchMadness continues Back 2 back papers in @NatureMedicine on combination MEK/ERK + autophagy inhibition in #PancreaticCa…
RT @NatRevClinOncol: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer: https://t.co/mqolkkPMF3
RT @NatRevClinOncol: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer: https://t.co/mqolkkPMF3
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer | Nature Medicine https://t.co/2scxjxmI1K
RT @NatRevClinOncol: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer: https://t.co/mqolkkPMF3
RT @NatRevClinOncol: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer: https://t.co/mqolkkPMF3
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer: https://t.co/mqolkkPMF3
chloroquineってオートファジーも阻害すんの?!(素人 やべえな。
RT @NatureMedicine: New research by Martin McMahon @UUtah & Channing Der @UNC_Lineberger describe co-inhibition of RAF-MEK-ERK signaling an…
RT @NatureMedicine: New research by Martin McMahon @UUtah & Channing Der @UNC_Lineberger describe co-inhibition of RAF-MEK-ERK signaling an…
Combined therapies are the future of pancreatic cancer treatment! It's great to see this exciting news out of not one, but two research labs. #DemandBetter #PancreaticCancer
RT @masayayamaguch: ERKとオートファジーを一緒に阻害することで、膵臓癌の治療への可能性。 昔オートファジーかじってたからオートファジーが創薬に関わってくるとなぜか嬉しい😊 しかしオートファジーの阻害はシンプルにChloroquineか。 https://…
RT @NatureMedicine: New research by Martin McMahon @UUtah & Channing Der @UNC_Lineberger describe co-inhibition of RAF-MEK-ERK signaling an…
RT @masayayamaguch: ERKとオートファジーを一緒に阻害することで、膵臓癌の治療への可能性。 昔オートファジーかじってたからオートファジーが創薬に関わってくるとなぜか嬉しい😊 しかしオートファジーの阻害はシンプルにChloroquineか。 https://…
RT @NatureMedicine: New research by Martin McMahon @UUtah & Channing Der @UNC_Lineberger describe co-inhibition of RAF-MEK-ERK signaling an…
RT @masayayamaguch: ERKとオートファジーを一緒に阻害することで、膵臓癌の治療への可能性。 昔オートファジーかじってたからオートファジーが創薬に関わってくるとなぜか嬉しい😊 しかしオートファジーの阻害はシンプルにChloroquineか。 https://…
RT @AndyBiotech: Two new papers in @NatureMedicine on MEK/ERKi + autophagy inhibition combination approach to treat #PancreaticCancer http…
RT @IshwariaMD: Current cost of a 30day supply of #hydroxychloroquine 1200mg/day: $63.10 at @Costco. Raise your hand if you think that pric…
RT @masayayamaguch: ERKとオートファジーを一緒に阻害することで、膵臓癌の治療への可能性。 昔オートファジーかじってたからオートファジーが創薬に関わってくるとなぜか嬉しい😊 しかしオートファジーの阻害はシンプルにChloroquineか。 https://…
RT @NatureMedicine: New research by Martin McMahon @UUtah & Channing Der @UNC_Lineberger describe co-inhibition of RAF-MEK-ERK signaling an…
RT @masayayamaguch: ERKとオートファジーを一緒に阻害することで、膵臓癌の治療への可能性。 昔オートファジーかじってたからオートファジーが創薬に関わってくるとなぜか嬉しい😊 しかしオートファジーの阻害はシンプルにChloroquineか。 https://…
Phenomenal work and exceptional mentorship from Channing Der to let Kirsten, postdoc in his lab and the first author to get the spotlight for her findings. https://t.co/WGt8hpbAEV https://t.co/G7RqBzklUq
ERKとオートファジーを一緒に阻害することで、膵臓癌の治療への可能性。 昔オートファジーかじってたからオートファジーが創薬に関わってくるとなぜか嬉しい😊 しかしオートファジーの阻害はシンプルにChloroquineか。 https://t.co/s8wha3ZUMZ
RT @AndyBiotech: Two new papers in @NatureMedicine on MEK/ERKi + autophagy inhibition combination approach to treat #PancreaticCancer http…
#PDAC がKRASとオートファジーに依存する秘密を解明?「To our surprise」、KRASの抑制がオートファジー流を増幅する。と。ERK阻害はKRAS抑制と同等、とも:UNC。 https://t.co/T7mFgfOryo
RT @SBLabUCSF: Very cool work that ends in actually treating a patient with the combo of Meki and chloroquine off label and off trial. Have…
Very cool work that ends in actually treating a patient with the combo of Meki and chloroquine off label and off trial. Haven’t seen that approach for a capstone figure before!
Congrats Kirsten! Awesome work!
RT @Aiims1742: #MarchMadness continues Back 2 back papers in @NatureMedicine on combination MEK/ERK + autophagy inhibition in #PancreaticCa…
RT @NeliMUlrich: Two top reads in @NatureMedicine! Lab breakthrough by Martin McMahon, Conan Kinsey and colleagues for new #pancreascancer…
RT @NatureMedicine: New research by Martin McMahon @UUtah & Channing Der @UNC_Lineberger describe co-inhibition of RAF-MEK-ERK signaling an…
Really interesting
RT @AndyBiotech: Two new papers in @NatureMedicine on MEK/ERKi + autophagy inhibition combination approach to treat #PancreaticCancer http…
RT @bryant_kl: Happy to finally share our study out today in @NatureMedicine proposing new treatment approach for #PancreaticCancer, publis…
RT @NatureMedicine: New research by Martin McMahon @UUtah & Channing Der @UNC_Lineberger describe co-inhibition of RAF-MEK-ERK signaling an…
RT @NatureMedicine: New research by Martin McMahon @UUtah & Channing Der @UNC_Lineberger describe co-inhibition of RAF-MEK-ERK signaling an…
RT @mcquadeMDLAc: But that CA19-9 curve ya’ll! 🤩 https://t.co/NYTDHluHMx
RT @AndyBiotech: Two new papers in @NatureMedicine on MEK/ERKi + autophagy inhibition combination approach to treat #PancreaticCancer http…
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer | Nature Medicine https://t.co/fVHMfLWvIC
RT @NatureMedicine: New research by Martin McMahon @UUtah & Channing Der @UNC_Lineberger describe co-inhibition of RAF-MEK-ERK signaling an…
RT @NatureMedicine: New research by Martin McMahon @UUtah & Channing Der @UNC_Lineberger describe co-inhibition of RAF-MEK-ERK signaling an…
RT @Aiims1742: #MarchMadness continues Back 2 back papers in @NatureMedicine on combination MEK/ERK + autophagy inhibition in #PancreaticCa…
RT @bryant_kl: Happy to finally share our study out today in @NatureMedicine proposing new treatment approach for #PancreaticCancer, publis…
Nuove speranze per il cancro pancreático legate all'hakeraggio del metabolismo energetico della cellula cancerosa. https://t.co/PQN0CJqip6
RT @ntjesch: Congratulations to @bryant_kl &@cjder23 ! Amazing work! Proud to be part of the @derlabunc @UNC_Lineberger https://t.co/QruTMh…