| Title |
The microbiome and critical illness
|
|---|---|
| Published in |
The Lancet Respiratory Medicine, December 2015
|
| DOI | 10.1016/s2213-2600(15)00427-0 |
| Pubmed ID | |
| Authors |
Robert P Dickson |
| Abstract |
The central role of the microbiome in critical illness is supported by a half century of experimental and clinical study. The physiological effects of critical illness and the clinical interventions of intensive care substantially alter the microbiome. In turn, the microbiome predicts patients' susceptibility to disease, and manipulation of the microbiome has prevented or modulated critical illness in animal models and clinical trials. This Review surveys the microbial ecology of critically ill patients, presents the facts and unanswered questions surrounding gut-derived sepsis, and explores the radically altered ecosystem of the injured alveolus. The revolution in culture-independent microbiology has provided the tools needed to target the microbiome rationally for the prevention and treatment of critical illness, holding great promise to improve the acute and chronic outcomes of the critically ill. |
X Demographics
The data shown below were collected from the profiles of 89 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 23 | 26% |
| United States | 8 | 9% |
| Switzerland | 2 | 2% |
| Spain | 2 | 2% |
| France | 2 | 2% |
| South Africa | 2 | 2% |
| Venezuela, Bolivarian Republic of | 2 | 2% |
| India | 1 | 1% |
| Singapore | 1 | 1% |
| Other | 8 | 9% |
| Unknown | 38 | 43% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 55 | 62% |
| Practitioners (doctors, other healthcare professionals) | 18 | 20% |
| Scientists | 14 | 16% |
| Science communicators (journalists, bloggers, editors) | 2 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 366 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| India | 1 | <1% |
| Greece | 1 | <1% |
| Australia | 1 | <1% |
| Unknown | 362 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 49 | 13% |
| Researcher | 47 | 13% |
| Student > Master | 36 | 10% |
| Other | 31 | 8% |
| Student > Bachelor | 26 | 7% |
| Other | 72 | 20% |
| Unknown | 105 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 114 | 31% |
| Agricultural and Biological Sciences | 38 | 10% |
| Biochemistry, Genetics and Molecular Biology | 24 | 7% |
| Immunology and Microbiology | 24 | 7% |
| Nursing and Health Professions | 15 | 4% |
| Other | 32 | 9% |
| Unknown | 119 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 175. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 December 2022.
All research outputs
#236,966
of 25,885,956 outputs
Outputs from The Lancet Respiratory Medicine
#228
of 2,912 outputs
Outputs of similar age
#3,624
of 396,995 outputs
Outputs of similar age from The Lancet Respiratory Medicine
#2
of 61 outputs
Altmetric has tracked 25,885,956 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,912 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 78.1. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 396,995 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 61 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.