@BillGates Today my father has returned home after being admitted to Songkhla Hospital on February 12, 2024. Doctors performed a CT scan and found a cerebral artery stenosis at the MCA of the brain. https://t.co/wkdWy8PwdA and https://t.co/M1cjrPCdaE http
Why do we use both aspirin and plavix for mild stroke or high risk TIA? It is all thanks, in part, to the POINT trial which showed lower risk of subsequent stroke, MI, or death 90 days later (N=4800 patient). 2/4 https://t.co/wJsDXWydLC https://t.co/RiJUqI
@BillGates Attached herewith is medicine of my father and the information that I find on internet to treat him as result of MRI brain. https://t.co/wkdWy8PwdA https://t.co/BYgFDnspit
The Point trial, however, showed an increased incidence of bleeding compared to the chance trial. This can be attributed to a higher loading of Plavix. 600 mg was used in the POINT trial compared to 300 mg in chance. https://t.co/p6iokOnDzg
@BillGates Because at that time my mother was still a bedridden patient. She died on October 28, 2019. After I read my father's brain MRI, I found he had a stroke. https://t.co/668UnKNYJF https://t.co/LcY5s52tb0
6/8 However, there was also an increase in major hemorrhage risk that continued to increase throughout the 90 days of DAPT (NNH=200) https://t.co/GB01uO9D07 https://t.co/o1NCwEZy6o
@bermudezsvj @RicardoSernax Si… 600 Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA | NEJM https://t.co/Cbf0AhzQQk
Clopidogrel & Aspirin in Acute Ischemic Stroke and others. https://t.co/tmTq36h689 To gain mechanistic & therapeutic insights into COVID-19: https://t.co/6ySOYUZzaD https://t.co/3q3H8aVLyL https://t.co/ZGNRi4lnsW Twitter: @DrLBoominathan [therap
A1 cont: and in this time period the benefits of reducing ischemic events with DAPT outweigh the risks of bleeding. This was shown in the CHANCE and POINT trials below. https://t.co/RfB7H3AQg7 https://t.co/4WrnKSeVfe
@fedebotta1 However, RCT of patients with minor AIS or high-risk TIA to aspirin alone or the combo of both aspirin+clopidogrel. Stopped early because of lower risk of major ischemic events but higher risk of major hemorrhage with the combo compared to a
Guidelines: Asp+clopidogrel x 21 days in NIHSS ≤3 Clopidogrel+Asp vs Asp+Placebo: clopidogrel beneficial primary outcome (stroke/MI/death @ 90days) https://t.co/M8YLtsLfzr Ticagrelor vs Aspirin: no change in primary outcome (stroke/MI/death) https://t.co
Point well taken :) The Chance trial was 300 mg.https://t.co/9hcWjrp0Bh
@MonicaDhakar @Tracey1milligan Because POINT was 600, right? https://t.co/0GYz3QFOXG
RT @NEJM: #VisualAbstract: In patients with minor ischemic stroke or TIA, aspirin + clopidogrel reduces risk of major ischemic events but i…
Asa w clopidrogel vs asa w placebo in Acute ischemic stroke, and short benefit term w more bleeding; #UMKCRCT; https://t.co/lO4ZtJzNQh
@ferbotto The trial should have compared AAS+TICA vs AAS+Clopidrogrel. Clopi+AAS is the standard of care of acute high risk AIT/minor CVA. https://t.co/kSiwGD1mmR https://t.co/mckrFOKXGI Lesson learnt from the chinese CHANCE trial & POINT trial. Grupo
@DFCapodanno THALES results in keeping with prev data (i.e. POINT trial, DAPT with clopidogrel vs. ASA alone in minor stroke or high risk TIA: ⬇️1.5%MACE ⬆️0.5% majBleed) https://t.co/ACvBHxYVDL ) As in PEGASUS remains unanswered wether ticagrelor is supe
RT @accpcritprn: Clopidogrel and aspirin in acute ischemic #stroke and high-risk TIA – POINT trial https://t.co/ltewoLgaXh #CritPRN
RT @accpcritprn: Clopidogrel and aspirin in acute ischemic #stroke and high-risk TIA – POINT trial https://t.co/ltewoLgaXh #CritPRN
Clopidogrel and aspirin in acute ischemic #stroke and high-risk TIA – POINT trial https://t.co/ltewoLgaXh #CritPRN
RT @Saudi_Pharma_07: Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA | NEJM https://t.co/kFvLSNEmHb
RT @Saudi_Pharma_07: Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA | NEJM https://t.co/kFvLSNEmHb
For secondary prevention: - Dual antiplatelet therapy (DAPT = ASA + Plavix) does prevent more strokes up to 90 days, but increases hemorrhage after ~21 days **CHANCE trial and POINT trial: https://t.co/SjlfkOzHst Updated suggestion: use DAPT for 7-21 da
RT @NormanJonasMD: Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA | NEJM https://t.co/ApYx2Cdgbs
RT @geriatricsdoc: #BGSconf point trial https://t.co/DWx5hOmEFD
RT @NormanJonasMD: Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA | NEJM https://t.co/ApYx2Cdgbs
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA | NEJM https://t.co/ApYx2Cdgbs
RT @geriatricsdoc: #BGSconf point trial https://t.co/DWx5hOmEFD
RT @geriatricsdoc: #BGSconf point trial https://t.co/DWx5hOmEFD
#BGSconf point trial https://t.co/DWx5hOmEFD
RT @EmmesCorp: The results from the Platelet Oriented Inhibition in New TIA & Minor Ischemic Stroke Trial (POINT), on which Emmes served as…
The results from the Platelet Oriented Inhibition in New TIA & Minor Ischemic Stroke Trial (POINT), on which Emmes served as CRC Operations Center, from @NEJM https://t.co/PeT10zCq4Y #BrainAwarenessWeek #BrainWeek @dana_fdn #BrainInjuryAwarenessMonth #
RT @kevinmb01: @jfernandezfr @ElkinBeltranMD POINT trial Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA | NEJM https://…
RT @HumanFact0rz: POINT-TIA: 300-600mg clopidogrel + ASA 81-325mg for 30 days following TIA in very high risk individuals https://t.co/qJz…
RT @davidcarr333: Thales is on the way which hopefully will clarify . Need to take a combination of POINT and CHANCE. Dual Anti platelet…
RT @HumanFact0rz: POINT-TIA: 300-600mg clopidogrel + ASA 81-325mg for 30 days following TIA in very high risk individuals https://t.co/qJz…
RT @HumanFact0rz: POINT-TIA: 300-600mg clopidogrel + ASA 81-325mg for 30 days following TIA in very high risk individuals https://t.co/qJz…
RT @HumanFact0rz: POINT-TIA: 300-600mg clopidogrel + ASA 81-325mg for 30 days following TIA in very high risk individuals https://t.co/qJz…
RT @HumanFact0rz: POINT-TIA: 300-600mg clopidogrel + ASA 81-325mg for 30 days following TIA in very high risk individuals https://t.co/qJz…
RT @HumanFact0rz: POINT-TIA: 300-600mg clopidogrel + ASA 81-325mg for 30 days following TIA in very high risk individuals https://t.co/qJz…
RT @HumanFact0rz: POINT-TIA: 300-600mg clopidogrel + ASA 81-325mg for 30 days following TIA in very high risk individuals https://t.co/qJz…
RT @davidcarr333: Thales is on the way which hopefully will clarify . Need to take a combination of POINT and CHANCE. Dual Anti platelet…
Thales is on the way which hopefully will clarify . Need to take a combination of POINT and CHANCE. Dual Anti platelet Therapy likely somewhere between 21-30 days. With the plavix load at 300 not 600. Respect the first 48 hours
POINT-TIA: 300-600mg clopidogrel + ASA 81-325mg for 30 days following TIA in very high risk individuals https://t.co/qJzadiSL1l 2x efficacy for stroke prevention vs ASA alone, especially in the first 2 weeks Increased risk of major bleeding at 90 days w
Though we are very proud of being part of this paper in the most prestigious journal (NEJM), its results speak to the myopic nature of clinical trials. The results, after work from dozens of institutions was that In patients with m…https://t.co/uNxV37je2C
Though we are very proud of being part of this paper in the most prestigious journal (NEJM), its results speak to the myopic nature of clinical trials. The results, after work from dozens of institutions was that In patients with m…https://t.co/llw8vPvKht
@Saudi_Pharma_07 According to CHANCE trail, the best duration for DAPT was 21days. Because it does not increase the risk of hemorrhage. On the other hand, new trail found that 90 days of DAPT associated with a higher risk of major hemorrhage. https://t.
RT @NEJM: #VisualAbstract: In patients with minor ischemic stroke or TIA, aspirin + clopidogrel reduces risk of major ischemic events but i…
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA - NEJM 2018 - #stroke #TIA - PubMed - NCBI https://t.co/LjDsPcyyMi
Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA. - PubMed - NCBI https://t.co/GsDqtsaQ1A
RT @DrPascalMeier: After minor ischaemic stroke or TIA, clopidogrel + aspirin -> lower risk of major ischaemic events but more major bleed…
RT @mitchelzoler: Prespecified POINT (https://t.co/DYFFXifTUR) analysis showed clopidogrel+aspirin had better ischemic protection vs asa o…
RT @mitchelzoler: Prespecified POINT (https://t.co/DYFFXifTUR) analysis showed clopidogrel+aspirin had better ischemic protection vs asa o…
Prespecified POINT (https://t.co/DYFFXifTUR) analysis showed clopidogrel+aspirin had better ischemic protection vs asa only & minimized hemorrhages during 21 days of treatment. Take away: Use DAPT for pts w minor #stroke or TIA & w/o A Fib for 21
Futher evidence regarding the use of dual antiplatelet therapy post stroke/TIA. https://t.co/bDj21iNR9V
RT @NEJM: #VisualAbstract: In patients with minor ischemic stroke or TIA, aspirin + clopidogrel reduces risk of major ischemic events but i…
RT @NEJM: Original Article: Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA https://t.co/pL4TKXZ5Sa Editorial: Antiplat…
RT @AbdulrazaqAlJa3: Since 2001, at KFSHRC Pharmacy Division, we are enjoying conducting weekly Journal Club. It is every Monday from 4-5 p…
RT @AbdulrazaqAlJa3: Since 2001, at KFSHRC Pharmacy Division, we are enjoying conducting weekly Journal Club. It is every Monday from 4-5 p…
RT @AbdulrazaqAlJa3: Since 2001, at KFSHRC Pharmacy Division, we are enjoying conducting weekly Journal Club. It is every Monday from 4-5 p…
RT @AbdulrazaqAlJa3: Since 2001, at KFSHRC Pharmacy Division, we are enjoying conducting weekly Journal Club. It is every Monday from 4-5 p…
RT @AbdulrazaqAlJa3: Since 2001, at KFSHRC Pharmacy Division, we are enjoying conducting weekly Journal Club. It is every Monday from 4-5 p…
We’re more than welcome to join us 😊
RT @AbdulrazaqAlJa3: Since 2001, at KFSHRC Pharmacy Division, we are enjoying conducting weekly Journal Club. It is every Monday from 4-5 p…
RT @AbdulrazaqAlJa3: Since 2001, at KFSHRC Pharmacy Division, we are enjoying conducting weekly Journal Club. It is every Monday from 4-5 p…
RT @AbdulrazaqAlJa3: Since 2001, at KFSHRC Pharmacy Division, we are enjoying conducting weekly Journal Club. It is every Monday from 4-5 p…
RT @AbdulrazaqAlJa3: Since 2001, at KFSHRC Pharmacy Division, we are enjoying conducting weekly Journal Club. It is every Monday from 4-5 p…
RT @AbdulrazaqAlJa3: Since 2001, at KFSHRC Pharmacy Division, we are enjoying conducting weekly Journal Club. It is every Monday from 4-5 p…
RT @AbdulrazaqAlJa3: Since 2001, at KFSHRC Pharmacy Division, we are enjoying conducting weekly Journal Club. It is every Monday from 4-5 p…
Since 2001, at KFSHRC Pharmacy Division, we are enjoying conducting weekly Journal Club. It is every Monday from 4-5 pm in Pharmacy Conference. Pharmacy practitioners are welcome to join! Next week is POINT Trial.. https://t.co/QUnMiZ
RT @NEJM: Original Article: Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA https://t.co/pL4TKXZ5Sa Editorial: Antiplat…
RT @NEJM: Original Article: Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA https://t.co/pL4TKXZ5Sa Editorial: Antiplat…
RT @JWatch: Look and learn from @NEJM's new #VisualAbstract: In patients with minor ischemic stroke or TIA, aspirin + clopidogrel reduces r…
RT @SimonGandevia: STROKE prevention: which is the best anti-platelet strategy? New informative data published. https://t.co/rfxTMxGG0m
RT @LouisMullie: Trials of dual antiplatelets for CVA/TIA - MATCH (2004): DAPT increases bleeding, does not reduce CVA recurrence. - CHAN…
Patients with minor #ischemicstroke who received both #clopidogrel and #aspirin had fewer major #ischemic events but more major hemorrhage in the first 3 months after the stroke than patients who only received aspirin. @NEJM https://t.co/M1CMf2dssh #academ
Many thanks to all of the patients and families playing a part in practice-changing clinical trials @VancouverStroke, including the recently published POINT and NAVIGATE-ESUS. https://t.co/xttsBM3Obn https://t.co/NstF6BYvTi
RT @Cardio_delaGuia: 🗞Tras accidente cerebrovascular isquémico leve o AIT de alto riesgo, los que recibieron clopidogrel + aspirina ➡️ meno…
Patients with minor #ischemicstroke who received both #clopidogrel and #aspirin had fewer major #ischemic events but more major hemorrhage in the first 3 months after the stroke than patients who only received aspirin. @NEJM https://t.co/M1CMf2dssh #academ
RT @DrPascalMeier: After minor ischaemic stroke or TIA, clopidogrel + aspirin -> lower risk of major ischaemic events but more major bleed…
RT @MaryCushmanMD: I wish @nejm would make these links #openaccess for big trials since it is hard to access via Twitter when one relies on…
RT @NEJM: #VisualAbstract: In patients with minor ischemic stroke or TIA, aspirin + clopidogrel reduces risk of major ischemic events but i…
RT @ENERI_BSAS: Clopidogrel + aspirina en pacientes con AIT de alto riesgo: menor riesgo de eventos isquémicos pero mayor riesgo de sangrad…
RT @RevistaMFSamfyc: Clopidogrel y aspirina en el ictus isquémico agudo y el AIT de alto riesgo https://t.co/7ATJnXnMqm PMID 29766750
RT @ENERI_BSAS: Clopidogrel + aspirina en pacientes con AIT de alto riesgo: menor riesgo de eventos isquémicos pero mayor riesgo de sangrad…
RT @ENERI_BSAS: Clopidogrel + aspirina en pacientes con AIT de alto riesgo: menor riesgo de eventos isquémicos pero mayor riesgo de sangrad…
@neuropuc el otro dia estuve conversando con compañeros sobre este estudio https://t.co/5y5Amgtn1a con una conclusión similar, pero con información sobre riesgo hemorrágico. Me dicen que es hemorragia en general, pero pensando en la epidemiología chilena t
RT @ENERI_BSAS: Clopidogrel + aspirina en pacientes con AIT de alto riesgo: menor riesgo de eventos isquémicos pero mayor riesgo de sangrad…
RT @NEJM: Original Article: Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA https://t.co/pL4TKXZ5Sa Editorial: Antiplat…
RT @NEJM: Original Article: Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA https://t.co/pL4TKXZ5Sa Editorial: Antiplat…
RT @ENERI_BSAS: Clopidogrel + aspirina en pacientes con AIT de alto riesgo: menor riesgo de eventos isquémicos pero mayor riesgo de sangrad…
STROKE prevention: which is the best anti-platelet strategy? New informative data published. https://t.co/rfxTMxGG0m
RT @NEJM: #VisualAbstract: In patients with minor ischemic stroke or TIA, aspirin + clopidogrel reduces risk of major ischemic events but i…
RT @ENERI_BSAS: Clopidogrel + aspirina en pacientes con AIT de alto riesgo: menor riesgo de eventos isquémicos pero mayor riesgo de sangrad…
RT @ENERI_BSAS: Clopidogrel + aspirina en pacientes con AIT de alto riesgo: menor riesgo de eventos isquémicos pero mayor riesgo de sangrad…