| Title |
Twelve-month outcomes of a randomized trial of a moderate-carbohydrate versus very low-carbohydrate diet in overweight adults with type 2 diabetes mellitus or prediabetes
|
|---|---|
| Published in |
Nutrition & Diabetes, December 2017
|
| DOI | 10.1038/s41387-017-0006-9 |
| Pubmed ID | |
| Authors |
Laura R. Saslow, Jennifer J. Daubenmier, Judith T. Moskowitz, Sarah Kim, Elizabeth J. Murphy, Stephen D. Phinney, Robert Ploutz-Snyder, Veronica Goldman, Rachel M. Cox, Ashley E. Mason, Patricia Moran, Frederick M. Hecht |
| Abstract |
Dietary treatment is important in management of type 2 diabetes or prediabetes, but uncertainty exists about the optimal diet. We randomized adults (n = 34) with glycated hemoglobin (HbA1c) > 6.0% and elevated body weight (BMI > 25) to a very low-carbohydrate ketogenic (LCK) diet (n = 16) or a moderate-carbohydrate, calorie-restricted, low-fat (MCCR) diet (n = 18). All participants were encouraged to be physically active, get sufficient sleep, and practice behavioral adherence strategies based on positive affect and mindful eating. At 12 months, participants in the LCK group had greater reductions in HbA1c levels (estimated marginal mean (EMM) at baseline = 6.6%, at 12 mos = 6.1%) than participants in MCCR group (EMM at baseline = 6.9%, at 12 mos = 6.7%), p = .007. Participants in the LCK group lost more weight (EMM at baseline = 99.9 kg, at 12 mos = 92.0 kg) than participants in the MCCR group (EMM at baseline = 97.5 kg, at 12 mos = 95.8 kg), p < .001. The LCK participants experienced larger reductions in diabetes-related medication use; of participants who took sulfonylureas or dipeptidyl peptidase-4 inhibitors at baseline, 6/10 in the LCK group discontinued these medications compared with 0/6 in the MCCR group (p = .005). In a 12-month trial, adults with elevated HbA1c and body weight assigned to an LCK diet had greater reductions in HbA1c, lost more weight, and reduced more medications than those instructed to follow an MCCR diet. |
X Demographics
The data shown below were collected from the profiles of 624 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 156 | 25% |
| United Kingdom | 52 | 8% |
| Canada | 29 | 5% |
| Australia | 24 | 4% |
| Spain | 14 | 2% |
| Brazil | 12 | 2% |
| South Africa | 12 | 2% |
| India | 9 | 1% |
| Netherlands | 7 | 1% |
| Other | 79 | 13% |
| Unknown | 230 | 37% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 453 | 73% |
| Practitioners (doctors, other healthcare professionals) | 117 | 19% |
| Scientists | 50 | 8% |
| Science communicators (journalists, bloggers, editors) | 4 | <1% |
Mendeley readers
The data shown below were compiled from readership statistics for 837 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 837 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 146 | 17% |
| Student > Master | 128 | 15% |
| Researcher | 54 | 6% |
| Other | 46 | 5% |
| Student > Postgraduate | 42 | 5% |
| Other | 142 | 17% |
| Unknown | 279 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 182 | 22% |
| Nursing and Health Professions | 135 | 16% |
| Biochemistry, Genetics and Molecular Biology | 47 | 6% |
| Agricultural and Biological Sciences | 46 | 5% |
| Psychology | 24 | 3% |
| Other | 96 | 11% |
| Unknown | 307 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 571. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 December 2023.
All research outputs
#42,101
of 25,729,842 outputs
Outputs from Nutrition & Diabetes
#5
of 485 outputs
Outputs of similar age
#914
of 449,985 outputs
Outputs of similar age from Nutrition & Diabetes
#1
of 12 outputs
Altmetric has tracked 25,729,842 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 485 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 31.5. This one has done particularly well, scoring higher than 98% of its peers.
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We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.