@piu_luce こういうツイートが年イチ位で流れて、元々知識があったので、根拠を論文で探しました。論文でなく、ブログやネット記事だと、日本人は特別に幸福/不幸というネタは書きやすいのか、肯定的な話ばかりですね。。
元の論文はこれのようです https://t.co/CFSKCQZyzl
7/ Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene https://t.co/GVEwDXKlYm https://t.co/vhr7SDGKI8 Outside of my wheelhouse, but the interaction between genes and environment on the development (or not) of complex e
2. Pese a lo inespecífico del término, el estrés (estresores vitales) aparecen como uno de los mayores predictores del desarrollo de depresión. https://t.co/EnweFQyHSI
RT @psiguanan: El único biomarcador sobre el que parece existir evidencia más sistemática es el cortisol, según esta revisión. Pero hay qu…
RT @psiguanan: El único biomarcador sobre el que parece existir evidencia más sistemática es el cortisol, según esta revisión. Pero hay qu…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @psiguanan: El único biomarcador sobre el que parece existir evidencia más sistemática es el cortisol, según esta revisión. Pero hay qu…
El único biomarcador sobre el que parece existir evidencia más sistemática es el cortisol, según esta revisión. Pero hay que tener en cuenta que otros factores psicológicos relacionados, como el estrés, siguen siendo mucho mejores predictores: https://t.c
RT @renebekkers: Third collaborative meta-analysis by Culverhouse et al. (2018), finds no reliable interaction. Imagine what we could have…
RT @HengartnerMP: @lindemann_jakob How old is this protocol? Recent research showed that there is no interaction between stressful life eve…
@lindemann_jakob How old is this protocol? Recent research showed that there is no interaction between stressful life events and serotonin transporter gene variants in depression and no association between genetic markers and treatment response. https://t.
Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression https://t.co/OSZKIZBi7H
これこれ。Culverhouse et al. (2017). Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression. Molecular Psychiatry, (April). https://t.co/Fwnfyk4yRF
@TonyMerriman2 Couldn't agree more. But one of the commentators in this article obviously hasn't read this paper, of which I'm proud to be an author: https://t.co/AE1rQ7GI9i
RT @EikoFried: @NoMoreStigmaMH The "yellow/blue" (serotonin transporter polymorphism) is pretty much falsified at this point I would say. B…
@NoMoreStigmaMH The "yellow/blue" (serotonin transporter polymorphism) is pretty much falsified at this point I would say. Border et al 2019 above looked into it, and there was another non replication recently: https://t.co/24fWjQt4Br
RT @niclas_kuper: @MarcusMunafo @StuartJRitchie Sounds like a very groundbreaking idea, I wonder if anyone has ever explored that! https:/…
@MarcusMunafo @StuartJRitchie Sounds like a very groundbreaking idea, I wonder if anyone has ever explored that! https://t.co/w2ULCpQPAK
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
Aha! At last, we can compare some genetic results with some old established associations to social variables. I take it "male" is coded 1 & female 0?
Sobering meta-analyses indicate so called candidate genes have limited bearing on psychiatric disorders. https://t.co/ZZEs7c1lnk https://t.co/zBOZsBqNjp
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
Follow the evidence .... https://t.co/4K7YAmel33
RT @JohnWhelan3: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depre... - PubMed - NCBI https://t.co/4K7YAmel33
RT @Martin_Ploederl: Example 2: S allele of the 5-HTTLPR serotonin transporter promoter region https://t.co/eqHX3rRESS
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @INM7_ISN: The era of candidate gene based "imaging genetics" was really important and has opened a whole new perspective. But it seems…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @RocaLecumberri: ⚠️ "If an interaction exist in which the S allele of #5HTTLPR increases risk of #depression only in stressed individual…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @leoschilbach: Depression, a stress-related disorder. Makes sense to me as a psychiatrist. https://t.co/S7v7pH7nsd
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @leoschilbach: Depression, a stress-related disorder. Makes sense to me as a psychiatrist. https://t.co/S7v7pH7nsd
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @ronald_fischer: The end of the 5HTTP x environment interaction saga? It was a promising story, but a single gene x environment interact…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @ronald_fischer: The end of the 5HTTP x environment interaction saga? It was a promising story, but a single gene x environment interact…
The end of the 5HTTP x environment interaction saga? It was a promising story, but a single gene x environment interaction should have been suspect early on. https://t.co/PSV0rDrOB1
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @INM7_ISN: The era of candidate gene based "imaging genetics" was really important and has opened a whole new perspective. But it seems…
RT @INM7_ISN: The era of candidate gene based "imaging genetics" was really important and has opened a whole new perspective. But it seems…
RT @INM7_ISN: The era of candidate gene based "imaging genetics" was really important and has opened a whole new perspective. But it seems…
RT @INM7_ISN: The era of candidate gene based "imaging genetics" was really important and has opened a whole new perspective. But it seems…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @INM7_ISN: The era of candidate gene based "imaging genetics" was really important and has opened a whole new perspective. But it seems…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
Interesting thread here @EvaAlisic
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @mpwpaulus: Can we put candidate gene approaches to bed? https://t.co/YISANOPQ0H
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @hardsci: This is both a super important finding, and an exemplar of a method that could be used more often for existing data - coordina…
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @leoschilbach: Depression, a stress-related disorder. Makes sense to me as a psychiatrist. https://t.co/S7v7pH7nsd
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @JCesarPL: El genotipo 5-HTTLPR no tiene ningún efecto sobre el riesgo de depresión ni interactúa con estresores vitales, pero los estre…
RT @leoschilbach: Depression, a stress-related disorder. Makes sense to me as a psychiatrist. https://t.co/S7v7pH7nsd
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @leoschilbach: Depression, a stress-related disorder. Makes sense to me as a psychiatrist. https://t.co/S7v7pH7nsd
Depression, a stress-related disorder. Makes sense to me as a psychiatrist.
RT @hardsci: For kicks, I just did an NIH RePORTER search for grants containing both "5-HTTLPR" and "depression". It returned 163 hits. How…
RT @INM7_ISN: The era of candidate gene based "imaging genetics" was really important and has opened a whole new perspective. But it seems…
RT @hardsci: For kicks, I just did an NIH RePORTER search for grants containing both "5-HTTLPR" and "depression". It returned 163 hits. How…
RT @INM7_ISN: The era of candidate gene based "imaging genetics" was really important and has opened a whole new perspective. But it seems…
RT @hardsci: For kicks, I just did an NIH RePORTER search for grants containing both "5-HTTLPR" and "depression". It returned 163 hits. How…
RT @INM7_ISN: The era of candidate gene based "imaging genetics" was really important and has opened a whole new perspective. But it seems…
It is interesting that 5HT may not be related with depression, and people pointed out how much grant money would then have been wasted. True, but also important is how much money and health would be wasted on inefficient pills...
RT @hardsci: For kicks, I just did an NIH RePORTER search for grants containing both "5-HTTLPR" and "depression". It returned 163 hits. How…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @hardsci: For kicks, I just did an NIH RePORTER search for grants containing both "5-HTTLPR" and "depression". It returned 163 hits. How…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…