RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @KinglaKing: The hits to introduce psych just keep coming... https://t.co/kDkqFYKITN
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
It's been a while since I took my exams in Clinical Psychology (and this is surely not my area of expertise), but this could be really big news. It suggests that the main risk factors for depression are stress and sex, and not genotype. #Depression #Ment
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
Esto-es-muy-importante.
El genotipo 5-HTTLPR no tiene ningún efecto sobre el riesgo de depresión ni interactúa con estresores vitales, pero los estresores vitales por ellos mismos sí. https://t.co/ewdQpCUHli
RT @hardsci: For kicks, I just did an NIH RePORTER search for grants containing both "5-HTTLPR" and "depression". It returned 163 hits. How…
RT @hardsci: For kicks, I just did an NIH RePORTER search for grants containing both "5-HTTLPR" and "depression". It returned 163 hits. How…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @hardsci: For kicks, I just did an NIH RePORTER search for grants containing both "5-HTTLPR" and "depression". It returned 163 hits. How…
RT @hardsci: For kicks, I just did an NIH RePORTER search for grants containing both "5-HTTLPR" and "depression". It returned 163 hits. How…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @hardsci: This is both a super important finding, and an exemplar of a method that could be used more often for existing data - coordina…
RT @hardsci: For kicks, I just did an NIH RePORTER search for grants containing both "5-HTTLPR" and "depression". It returned 163 hits. How…
RT @hardsci: For kicks, I just did an NIH RePORTER search for grants containing both "5-HTTLPR" and "depression". It returned 163 hits. How…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @JosephineAuPsy: Never understood why people seem to value biomarkers so more than psychological constructs even when the latter are mor…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @JosephineAuPsy: Never understood why people seem to value biomarkers so more than psychological constructs even when the latter are mor…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
Never understood why people seem to value biomarkers so more than psychological constructs even when the latter are more robust predictors, just like how medication trials get so much more funding than psychosocial interventions in treating suicidality #
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @hardsci: This is both a super important finding, and an exemplar of a method that could be used more often for existing data - coordina…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
Can we put candidate gene approaches to bed?
Kan vi släppa depression är "kemisk obalans i hjärnan" tills vi faktiskt hittar fynd som stöder det.
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
The hits to introduce psych just keep coming...
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
RT @EikoFried: New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#seroto…
New N~39,000 meta-analysis finds #depression is predicted by - sex (OR=0.6) - stress (OR=2.2) but not by - 5-HTTLPR (#serotonin transporter polymorphism) - 5-HTTLPR*stress interaction Raises doubts where previous findings come from (via @JamieLarsH). htt
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
RT @JamieLarsH: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression https://t.co/1gFvJFDEUh n=38 802! https://t.co/TLPxLHtxZv
ストレス環境下では5-HTTLPRのSアレルが鬱病リスクを増加するという仮説が議論を呼んできた。しかし、ヨーロッパ人の遺伝子型に対するメタ分析を行なった結果、ストレスと5-HTTLPR遺伝子型には一般に相互作用は見られなかった。https://t.co/DWX7NKR0g9 KA
@mniemivirta @ivanpuopolo @alekalenius @jussikniemela Ilmaiseksi luettavissa täällä: https://t.co/YQUD2J8Bvc
@mniemivirta @ivanpuopolo @alekalenius @jussikniemela Harmi vain, että tämänkin yhden geenimuodon ja ympäristön välisen interaktion todellisuus on hyvin kyseenalainen. Tässä tuore meta-analyysi (31 datasettiä, n=38 800): ei tue efektiä. https://t.co/8K4tX
RT @Martin_Ploederl: Example 2: S allele of the 5-HTTLPR serotonin transporter promoter region https://t.co/eqHX3rRESS
Example 2: S allele of the 5-HTTLPR serotonin transporter promoter region https://t.co/eqHX3rRESS
RT @tsuyomiyakawa: 強いストレスを経験した場合、セロトニントランスポーター遺伝子の多型がうつ病のリスクに影響するというサイエンス論文https://t.co/t8IrfH1OUM は7000回以上引用された著名論文。それが大規模研究によりほぼ完全否定。 htt…
RT @tsuyomiyakawa: 強いストレスを経験した場合、セロトニントランスポーター遺伝子の多型がうつ病のリスクに影響するというサイエンス論文https://t.co/t8IrfH1OUM は7000回以上引用された著名論文。それが大規模研究によりほぼ完全否定。 htt…
RT @tsuyomiyakawa: 強いストレスを経験した場合、セロトニントランスポーター遺伝子の多型がうつ病のリスクに影響するというサイエンス論文https://t.co/t8IrfH1OUM は7000回以上引用された著名論文。それが大規模研究によりほぼ完全否定。 htt…
RT @tsuyomiyakawa: 強いストレスを経験した場合、セロトニントランスポーター遺伝子の多型がうつ病のリスクに影響するというサイエンス論文https://t.co/t8IrfH1OUM は7000回以上引用された著名論文。それが大規模研究によりほぼ完全否定。 htt…
RT @tsuyomiyakawa: 強いストレスを経験した場合、セロトニントランスポーター遺伝子の多型がうつ病のリスクに影響するというサイエンス論文https://t.co/t8IrfH1OUM は7000回以上引用された著名論文。それが大規模研究によりほぼ完全否定。 htt…
RT @tsuyomiyakawa: 強いストレスを経験した場合、セロトニントランスポーター遺伝子の多型がうつ病のリスクに影響するというサイエンス論文https://t.co/t8IrfH1OUM は7000回以上引用された著名論文。それが大規模研究によりほぼ完全否定。 htt…
RT @Tokyo6Heart: ストレス × 5-HTTLPR遺伝子多型の交互作用が抑うつと強い関連を示さないというメタ分析論文。個人的に今期一の衝撃論文なんだが…。Culverhouse et al. (2018). Collaborative meta-analysis…
ストレス × 5-HTTLPR遺伝子多型の交互作用が抑うつと強い関連を示さないというメタ分析論文。個人的に今期一の衝撃論文なんだが…。Culverhouse et al. (2018). Collaborative meta-analysis finds no evidence of a strong interaction... Mol Psychiatry, 23, 133-142. https://t.co/orOUmT4KCE
RT @pfanderson: Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to…
Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression. https://t.co/xWN2oCafqQ | https://t.co/i9nENlq565 "of modest effect size and only observable in limi
RT @TiffanyCheingHo: Important null finding: no evidence that 5-HTTLPR genotype moderates the association between stress and developing dep…
RT @KirkegaardEmil: When will people start using more realistic priors on gene x environment interactions? Realistic = sparse, very sparse…
RT @AmirSariaslan: Yet another gene-environment interaction failed replication: https://t.co/FDixRdmdvB https://t.co/Ogp07vXnEp
RT @KirkegaardEmil: When will people start using more realistic priors on gene x environment interactions? Realistic = sparse, very sparse…
RT @macordero: 5-HTTLPR do NOT interact with stressful life events to change risk of depression in human populations. So many wrong clinica…
RT @KirkegaardEmil: When will people start using more realistic priors on gene x environment interactions? Realistic = sparse, very sparse…
5-HTTLPR do NOT interact with stressful life events to change risk of depression in human populations. So many wrong clinical hypothesis as consequence of small samples and testing targeted genes. https://t.co/WFRyqv3Dyk
When will people start using more realistic priors on gene x environment interactions? Realistic = sparse, very sparse indeed, big fat point on the 0. https://t.co/S4NGh8cEYY
Yet another gene-environment interaction failed replication: https://t.co/FDixRdmdvB https://t.co/Ogp07vXnEp