RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
Isn’t this idea already known though…? Basic biology concept that RNA enrichment isn’t always a readout of functional protein levels
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
Expression of some genes enriched in the brain only on protein level || A Quantitative Proteome Map of the Human Body: Cell https://t.co/JIGeJUrL0e
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @Eric_Chevet: A Quantitative Proteome Map of the Human Body https://t.co/AQXM8sVYU9
RT @Ruth_Walks: Really cool paper comparing protein to RNA levels across 32 normal human tissues. 6,357 proteins were present in all 32 tis…
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
Really cool paper comparing protein to RNA levels across 32 normal human tissues. 6,357 proteins were present in all 32 tissue types but there were many proteins not enriched at an transcript level showing the importance of #multiomics #Science https://t.c
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
That's interesting... https://t.co/7eEzlhrJsL
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
A Quantitative Proteome Map of the Human Body: Cell https://t.co/YxlVbVTp7d
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
Another justification for binary encoding of RNA-Seq data…
RT @Eric_Chevet: A Quantitative Proteome Map of the Human Body https://t.co/AQXM8sVYU9
A Quantitative Proteome Map of the Human Body https://t.co/AQXM8sVYU9
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
@raabgraham_lab
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
An amazing resource to be marked. Protein employs RNA to make it well-dressed and sociable with other partners.
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
Interesting study and the pituitary is even included! 🎉 Not done at sc resolution but still a great resource.
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
RT @JasonSynaptic: “our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which can…
“our study demonstrated that protein tissue-enrichment information can explain phenotypes of genetic diseases, which cannot be obtained by transcript information alone.” Large discordance between mRNA and protein enrichment! Now what RNA-seq folks?! https:
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
RT @slavov_n: Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophy…
Proteins known to be disrupted by disease-associated mutations are enriched in tissues that manifest disease-related pathophysiology. In many cases, the corresponding RNAs did not show the same enrichment. https://t.co/jQvoscPmab https://t.co/QsHvnDiB9e
@willmacnair RNA-seq is not perfect but still very useful. Large studies show RNA/Protein correlations ~0.45-50 suggesting they can be used for most things. I think the gap is justified by technological maturity, availability, and sensitivity https://t.c
RT @KVittingSeerup: @slavov_n By nature, they cannot be completely independent (no mRNA -> no protein). The large-scale studies I know of s…
RT @KVittingSeerup: @slavov_n By nature, they cannot be completely independent (no mRNA -> no protein). The large-scale studies I know of s…
RT @KVittingSeerup: @slavov_n By nature, they cannot be completely independent (no mRNA -> no protein). The large-scale studies I know of s…
RT @KVittingSeerup: @slavov_n By nature, they cannot be completely independent (no mRNA -> no protein). The large-scale studies I know of s…
@slavov_n By nature, they cannot be completely independent (no mRNA -> no protein). The large-scale studies I know of shows correlations in the ~0.45-50 which is neither perfect nor independent 😉 GTEx: https://t.co/UX79RKCFDv TCGA: https://t.co/kaTnvrx
RT @lizworthey: A Quantitative Proteome Map of the Human Body https://t.co/mbbkCS2WUl
A Quantitative Proteome Map of the Human Body https://t.co/mbbkCS2WUl
RT @learningbioinfo: A Quantitative Proteome Map of the Human Body https://t.co/jkRYnrt06p https://t.co/gTiNjGP6Rs
A Quantitative Proteome Map of the Human Body https://t.co/jkRYnrt06p https://t.co/gTiNjGP6Rs
RT @ypriverol: @pwilmarth Thanks, @pwilmarth. This is a comparison between multiple tissue proteomes (IBAQ) vs Gtex TMT expression (https:/…
RT @ypriverol: @pwilmarth Thanks, @pwilmarth. This is a comparison between multiple tissue proteomes (IBAQ) vs Gtex TMT expression (https:/…
@pwilmarth Thanks, @pwilmarth. This is a comparison between multiple tissue proteomes (IBAQ) vs Gtex TMT expression (https://t.co/puxM1KVi7M). I'm probably missing something? https://t.co/2iErshgKRs
RT @jochwenk: A Quantitative Proteome Map of the Human Body by @Snyder_Lab_SU as one of the amazing GTEx papers published today https://t.c…
RRIDs were included in the Cell paper "A Quantitative Proteome Map of the Human Body" (https://t.co/POfetcVzAQ). We appreciate the author's support of reproducibility. #ReproducibleResearch #accelerateopenscience
The authors of "A Quantitative Proteome Map of the Human Body" (https://t.co/POfetcVzAQ) included RRIDs in their paper! Thank you for making your #methodsmatter. #reproducibility
A Quantitative Proteome Map of the Human Body https://t.co/QOcjxUGzjC
"A Quantitative Proteome Map of the Human Body" Jiang L, Wang M [..] Snyder MP. Cell. 2020-09-10. https://t.co/YTE1mr5TUe GTEx consortium 12,627 genes/32 normal human tissues
RT @SnyderShot: Our eGTEX proteomics paper is out. GTEX gets proteomics! https://t.co/3A5BL0WwKQ
@slavov_n @JProteomeRes How does this compare to some of the other maps out there? Eg A Quantitative Proteome Map of the Human Body https://t.co/lXAC8UGr3O
Constitutive secretion of proteins to other tissues is one major cause of the significant negative correlation and discordance of protein and RNA https://t.co/lWavTj4YmE
Today we invite you to read a CELL publication entitled: “A Quantitative Proteome Map of the Human Body”, with interesting results regarding the benefits of protein levels understanding on human tissues: https://t.co/bG2zaiWGv1 #Research #Proteomics https
RT @Prof_M_Ristow: Quantitative #proteome map of the #human body. #GTEX https://t.co/24AfwEzlEH https://t.co/vX0FPDl0xe
RT @Prof_M_Ristow: Quantitative #proteome map of the #human body. #GTEX https://t.co/24AfwEzlEH https://t.co/vX0FPDl0xe
RT @Prof_M_Ristow: Quantitative #proteome map of the #human body. #GTEX https://t.co/24AfwEzlEH https://t.co/vX0FPDl0xe
RT @Prof_M_Ristow: Quantitative #proteome map of the #human body. #GTEX https://t.co/24AfwEzlEH https://t.co/vX0FPDl0xe
RT @Prof_M_Ristow: Quantitative #proteome map of the #human body. #GTEX https://t.co/24AfwEzlEH https://t.co/vX0FPDl0xe
Quantitative #proteome map of the #human body. #GTEX https://t.co/24AfwEzlEH https://t.co/vX0FPDl0xe
protein and rna
RT @CellCellPress: New resource out now! A #quantitative #proteome map of the human #body. https://t.co/2re7Z1J6t1 @Stanford https://t.co/s…
Very useful new #proteome #massspectrometry human body map resource - we will definitely use https://t.co/PGICPrmdW8. Whats your fave organ or cell? Thank you to authors @Stanford
RT @CellCellPress: New resource out now! A #quantitative #proteome map of the human #body. https://t.co/2re7Z1J6t1 @Stanford https://t.co/s…
RT @CellCellPress: New resource out now! A #quantitative #proteome map of the human #body. https://t.co/2re7Z1J6t1 @Stanford https://t.co/s…