| Title |
Circadian autophagy rhythm: a link between clock and metabolism?
|
|---|---|
| Published in |
Trends in Endocrinology & Metabolism, April 2012
|
| DOI | 10.1016/j.tem.2012.03.004 |
| Pubmed ID | |
| Authors |
Di Ma, Siming Li, Matthew M. Molusky, Jiandie D. Lin |
| Abstract |
Nutrient and energy metabolism in mammals exhibits a strong diurnal rhythm that aligns with the body clock. Circadian regulation of metabolism is mediated through reciprocal signaling between the clock and metabolic regulatory networks. Recent work has demonstrated that autophagy is rhythmically activated in a clock-dependent manner. Because autophagy is a conserved biological process that contributes to nutrient and cellular homeostasis, its cyclic induction may provide a novel link between clock and metabolism. This review discusses the mechanisms underlying circadian autophagy regulation, the role of rhythmic autophagy in nutrient and energy metabolism, and its implications in physiology and metabolic disease. |
X Demographics
The data shown below were collected from the profiles of 45 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 7 | 16% |
| United Kingdom | 2 | 4% |
| India | 2 | 4% |
| Brazil | 1 | 2% |
| Comoros | 1 | 2% |
| France | 1 | 2% |
| Canada | 1 | 2% |
| Czechia | 1 | 2% |
| Australia | 1 | 2% |
| Other | 1 | 2% |
| Unknown | 27 | 60% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 29 | 64% |
| Practitioners (doctors, other healthcare professionals) | 10 | 22% |
| Scientists | 4 | 9% |
| Science communicators (journalists, bloggers, editors) | 2 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 178 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 2 | 1% |
| Brazil | 1 | <1% |
| Israel | 1 | <1% |
| Canada | 1 | <1% |
| Spain | 1 | <1% |
| Japan | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 170 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 35 | 20% |
| Researcher | 31 | 17% |
| Student > Master | 22 | 12% |
| Student > Bachelor | 13 | 7% |
| Professor > Associate Professor | 10 | 6% |
| Other | 32 | 18% |
| Unknown | 35 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 53 | 30% |
| Biochemistry, Genetics and Molecular Biology | 33 | 19% |
| Medicine and Dentistry | 19 | 11% |
| Neuroscience | 16 | 9% |
| Nursing and Health Professions | 4 | 2% |
| Other | 18 | 10% |
| Unknown | 35 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 28. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 January 2023.
All research outputs
#1,421,517
of 25,765,370 outputs
Outputs from Trends in Endocrinology & Metabolism
#122
of 1,587 outputs
Outputs of similar age
#7,466
of 174,952 outputs
Outputs of similar age from Trends in Endocrinology & Metabolism
#3
of 23 outputs
Altmetric has tracked 25,765,370 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,587 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.3. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 174,952 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.