@murideeg @Steve_Sailer @JAMA_current The mechanism of infection is most expressed in nasal tissue, iow it's the main target. As for Africa's data, that could be a result of incomplete testing and/or population density. https://t.co/lPE5v3POIu
"Seen this multiple times: study does sequencing, but not providing information on how to retrieve raw data (no link to SRA or "upon request"). " https://t.co/aolRwjV6ZX "We had to click Show more replies to find microRNApro's reply to this tweet."
@sebboeg It's an example of gas-lighting to support stupid theories of mutation-driven evolution. See also: https://t.co/CcvwHHD80i
@assassinroyal_ @raoult_didier Cela n'a rien à voir, le #coronavirus est très contagieux car il se fixe aux récepteurs ACE2 très présent dans le nez des adultes https://t.co/hrCtztnh9a
۸۱/ در نتیجه به نظر میرسد که اپیتلیوم تنفسی (RE) به عنوان مخزن ویروسی #کووید۱۹ عمل میکند. https://t.co/cxQp8HcAsH در تحقیقی جداگانه هم مشخص شد که علاوه بر اپیتلیوم تنفسی (RE)، ژنهای ACE2 و TMPRSS2 در اپیتلیوم بویایی (RO) هم بیان میشوند. https://t.co/mMRCQ
RT @angie_rasmussen: 2 (cont). At least one study shows that ACE2 transcripts (mRNA, which encode proteins) and one of these co-factors, TM…
@drakchaurasia TMPRSS isoforms are highly expressed in ACE2+ cells within the nasal mucosa: https://t.co/b91VWsjo7R Hence SARS-CoV would be missing out on this faster entry route compared to SARS-CoV-2. Note SARS disease progression was typically slower
RT @EricTopol: Single-cell RNA seq study of healthy tissue to determine the precise path of how #COVID19 enters nose cells https://t.co/i5M…
۱۹/ در سلولهای آلوئول (سلولهای AT2) در اعماق ریه محدود میشود. اما مشخص شده است که ACE2 در برخی از سلولهای ترشحی داخل بینی هم بیان میشود (https://t.co/YPIZipmwZl). در نتیجه به نظر میرسد که کرونا ویروس از همان ابتدای ورود به بدن، سلولهای موجود در نازوفارنکس
点鼻薬の有効性の話は、他の論文でもあったかと。 また、オレ独自仮説を恥ずかしながら書いた記憶がw >https://t.co/YhLhgTpUD4 杯細胞にウイルス感染を受けると嗅覚障害が出るかも、という話をしましたw 肺でのウイルス増殖を阻止できれば大抵の場合重症化を防げるので、鼻は大事だと思うw
RT @buzzyhelps: New investigation supports what @AmyBaxterMD has been saying about nasal irrigation. In recent Facebook Live broadcasts, sh…
@PEYESTRO @richardursomd @realDonaldTrump @IngrahamAngle @SteveFDA @drsimonegold @jennybethm Virus gained entry through TMPRSS2 and not ACE2 in that study of Calu3. ACE2 are in abandance in nasal epithelium and HCQ blocks ACE2 and prevents viral entry. So
@g_mundaw Also because the nose has a very high density of ACE2 receptors, which the virus uses to get in. https://t.co/ZVqwxm1zLk
@SmootSienna @gmicksmith @_atanas_ @EricsElectrons What did they think they are swabbin noses left and right for? https://t.co/v91sR57ICw // https://t.co/DqKcJ5lWaq // explore with caution. https://t.co/sPFMR0cUuH
RT @WvSchaik: I feel the government should launch a campaign on how to wear a face mask, particularly that it needs to cover the nose as we…
RT @WvSchaik: I feel the government should launch a campaign on how to wear a face mask, particularly that it needs to cover the nose as we…
RT @WvSchaik: I feel the government should launch a campaign on how to wear a face mask, particularly that it needs to cover the nose as we…
RT @WvSchaik: I feel the government should launch a campaign on how to wear a face mask, particularly that it needs to cover the nose as we…
RT @WvSchaik: I feel the government should launch a campaign on how to wear a face mask, particularly that it needs to cover the nose as we…
RT @WvSchaik: I feel the government should launch a campaign on how to wear a face mask, particularly that it needs to cover the nose as we…
RT @WvSchaik: I feel the government should launch a campaign on how to wear a face mask, particularly that it needs to cover the nose as we…
RT @WvSchaik: I feel the government should launch a campaign on how to wear a face mask, particularly that it needs to cover the nose as we…
RT @WvSchaik: I feel the government should launch a campaign on how to wear a face mask, particularly that it needs to cover the nose as we…
RT @WvSchaik: I feel the government should launch a campaign on how to wear a face mask, particularly that it needs to cover the nose as we…
RT @WvSchaik: I feel the government should launch a campaign on how to wear a face mask, particularly that it needs to cover the nose as we…
RT @WvSchaik: I feel the government should launch a campaign on how to wear a face mask, particularly that it needs to cover the nose as we…
RT @WvSchaik: I feel the government should launch a campaign on how to wear a face mask, particularly that it needs to cover the nose as we…
RT @WvSchaik: I feel the government should launch a campaign on how to wear a face mask, particularly that it needs to cover the nose as we…
@capitalcheck @jimcramer " In symptomatic patients, nasal swabs have yielded higher viral loads than throat swabs4." If receptors are more concentrated in eyes and noses, then we can deduce these are the onramps to infection. masks w noses out still ok?
@drbeen_medical I assume his treatment is mid to late stage Covid-19 (hyperinflammatory) disease, not early stage? Since ACE-2 is expressed in greater qty in upper respiratory mucosa vs pulmonary epithelium, why not target that area during the early infect
@OutOfTheDarkAge @C_H_Industries @RegimeChangeBC #Hydroxychloroquine monotherapy also ineffective there. Furin is ubiquitously expressed and vascular endothelial cells express lots of TMPRSS2. HCQ alone might help in kidneys, but this is not a primary i
RT @dilangzhong: SARS-CoV-2进入因子ACE2与先天免疫基因一起在鼻上皮细胞中高度表达 PS:路德曾说过,CCP virus主要是通过鼻腔的ACE2侵入人体。 https://t.co/0JG2H3eBew
RT @dilangzhong: SARS-CoV-2进入因子ACE2与先天免疫基因一起在鼻上皮细胞中高度表达 PS:路德曾说过,CCP virus主要是通过鼻腔的ACE2侵入人体。 https://t.co/0JG2H3eBew
RT @dilangzhong: SARS-CoV-2进入因子ACE2与先天免疫基因一起在鼻上皮细胞中高度表达 PS:路德曾说过,CCP virus主要是通过鼻腔的ACE2侵入人体。 https://t.co/0JG2H3eBew
RT @dilangzhong: SARS-CoV-2进入因子ACE2与先天免疫基因一起在鼻上皮细胞中高度表达 PS:路德曾说过,CCP virus主要是通过鼻腔的ACE2侵入人体。 https://t.co/0JG2H3eBew
RT @dilangzhong: SARS-CoV-2进入因子ACE2与先天免疫基因一起在鼻上皮细胞中高度表达 PS:路德曾说过,CCP virus主要是通过鼻腔的ACE2侵入人体。 https://t.co/0JG2H3eBew
RT @dilangzhong: SARS-CoV-2进入因子ACE2与先天免疫基因一起在鼻上皮细胞中高度表达 PS:路德曾说过,CCP virus主要是通过鼻腔的ACE2侵入人体。 https://t.co/0JG2H3eBew
RT @dilangzhong: SARS-CoV-2进入因子ACE2与先天免疫基因一起在鼻上皮细胞中高度表达 PS:路德曾说过,CCP virus主要是通过鼻腔的ACE2侵入人体。 https://t.co/0JG2H3eBew
RT @dilangzhong: SARS-CoV-2进入因子ACE2与先天免疫基因一起在鼻上皮细胞中高度表达 PS:路德曾说过,CCP virus主要是通过鼻腔的ACE2侵入人体。 https://t.co/0JG2H3eBew
RT @dilangzhong: SARS-CoV-2进入因子ACE2与先天免疫基因一起在鼻上皮细胞中高度表达 PS:路德曾说过,CCP virus主要是通过鼻腔的ACE2侵入人体。 https://t.co/0JG2H3eBew
RT @dilangzhong: SARS-CoV-2进入因子ACE2与先天免疫基因一起在鼻上皮细胞中高度表达 PS:路德曾说过,CCP virus主要是通过鼻腔的ACE2侵入人体。 https://t.co/0JG2H3eBew
RT @dilangzhong: SARS-CoV-2进入因子ACE2与先天免疫基因一起在鼻上皮细胞中高度表达 PS:路德曾说过,CCP virus主要是通过鼻腔的ACE2侵入人体。 https://t.co/0JG2H3eBew
RT @dilangzhong: SARS-CoV-2进入因子ACE2与先天免疫基因一起在鼻上皮细胞中高度表达 PS:路德曾说过,CCP virus主要是通过鼻腔的ACE2侵入人体。 https://t.co/0JG2H3eBew
RT @dilangzhong: SARS-CoV-2进入因子ACE2与先天免疫基因一起在鼻上皮细胞中高度表达 PS:路德曾说过,CCP virus主要是通过鼻腔的ACE2侵入人体。 https://t.co/0JG2H3eBew
RT @dilangzhong: SARS-CoV-2进入因子ACE2与先天免疫基因一起在鼻上皮细胞中高度表达 PS:路德曾说过,CCP virus主要是通过鼻腔的ACE2侵入人体。 https://t.co/0JG2H3eBew
RT @BaudotAnais: And finally @ChrBecavin, human single-cell atlas of human airways! https://t.co/kLUKi46y54 Special focus on ACE2 expressio…
And finally @ChrBecavin, human single-cell atlas of human airways! https://t.co/kLUKi46y54 Special focus on ACE2 expression https://t.co/4VpL0Jj2Lt
The second paper in Nature Medecine: https://t.co/hjVbJNSaw3
@mauricedehond Vraag 3. "Notably, nasal epithelial cells, including two previously described clusters of goblet cells and one cluster of ciliated cells, show the highest ACE2 expression among all investigated cells in the respiratory tree (Fig. 1b)." htt
New investigation supports what @AmyBaxterMD has been saying about nasal irrigation. In recent Facebook Live broadcasts, she's talked about it as a way to prevent the travel of COVID-19 through the nasal passages to the lungs. Strong support here. #covid19
RT @kazukazu721: 「SARS-CoV-2エントリー因子は、自然免疫遺伝子とともに鼻上皮細胞で高度に発現されています」 やっぱり鼻ですか。 https://t.co/PFd9mrNdDz
@IntJStroke @focastilla @WorldStrokeOrg @OpheliaDeroy @KaraCHoover Yes, several articles: Recent paper in Nature Medcine: https://t.co/LmO2rU9YLP
@Rea3000 SARS-CoV2 (causes COVID) bi ds to cells via the ACE2 receptor. https://t.co/u1DIIksjPB https://t.co/z5CZ0ZeHy3
@notdred I think this was it https://t.co/D0s9JNTipG
@mrsoydan00 SARS-CoV-2 virüsünün tutunarak hücre içerisine girdiği ACE2 reseptörleri nasal epitel hücrelerinde daha fazla olduğu gösterilmiş ve semptom görülme öncesi dönemde buralardaki salgıyla ilerliyor olabilir deniliyor. Burnu kapatmak önemli. https:
Los factores de entrada del SARS-CoV-2 están altamente expresados en las células epiteliales nasales junto con los genes inmunes innatos https://t.co/MMifYhVxqx
@yadindudai @SmellSpace_IL "SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune gene" Nat med. https://t.co/AR5QdPCmfE On expression of ACE2 in multiple tissues
@DocMoschos Sterghios, I did see nasal presence of the receptor. Am I reading wrongly? https://t.co/A1V6yVCF5v
RT @BioDecoded: SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes | Nature Medicine…
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes | Nature Medicine https://t.co/gka2rBMDJg
@KirstieJBrewer @prestofurioso good work, especially as Sanger Cell Atlas analysis suggests nasal droplets most infectious! https://t.co/1t3OFPeT4S
RT @alexander_minh: A study which explores how novel SARS-CoV-2 #coronavirus gets into the human airway via nasal goblet & ciliated cells…
医学関係の方々や、コロナリサーチに興味のある方におすすめします、この
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes | Nature Medicine https://t.co/GvW6Ik546k
RT @teichlab: Here the link to the HCA https://t.co/BvPyH4xCxK and the cited study by Sungnak et al https://t.co/yzRMr10Dli https://t.co/47…
Here the link to the HCA https://t.co/BvPyH4xCxK and the cited study by Sungnak et al https://t.co/yzRMr10Dli
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes @nature https://t.co/VXtX2sLb3c
potential explanation for anosmia (should this now be included as early symptom for self isolation and wearing a mask, particularly as nasal droplets may have high viral load?)
RT @sutheerak: SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes | Nature Medicine…
RT @momo0078: SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes https://t.co/qiD8jM…
RT @momo0078: ウイルス学:多数の組織の遺伝学的解析結果は、SARS-CoV-2が鼻の特定の細胞に感染する可能性を示している | Nature Medicine | Nature Research: https://t.co/lU0nmGrbv0
@AlgitaLfc @kazkurtoli While it may be transmitted through your eyes, the nose is actually the primary entrypoint for Covid. https://t.co/RR2ynlUfBy
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes https://t.co/qiD8jMdEeR
ウイルス学:多数の組織の遺伝学的解析結果は、SARS-CoV-2が鼻の特定の細胞に感染する可能性を示している | Nature Medicine | Nature Research: https://t.co/lU0nmGrbv0
RT @NeBanovich: Here's the three current papers around this work: https://t.co/YGhVTLNjK1 https://t.co/h0vmBRAA8t https://t.co/ffahihdArr…
RT @NeBanovich: Here's the three current papers around this work: https://t.co/YGhVTLNjK1 https://t.co/h0vmBRAA8t https://t.co/ffahihdArr…
RT @NeBanovich: Here's the three current papers around this work: https://t.co/YGhVTLNjK1 https://t.co/h0vmBRAA8t https://t.co/ffahihdArr…
Here's the three current papers around this work: https://t.co/YGhVTLNjK1 https://t.co/h0vmBRAA8t https://t.co/ffahihdArr #BoG20
RT @Slight_Bright: Nature Medicineにちょうど論文出てた。鼻の胚細胞や粘液産生の繊毛細胞でACE2とTMPRSS2が高発現していることが明らかに、と。>ウイルス学:多数の組織の遺伝学的解析結果は、SARS-CoV-2が鼻の特定の細胞に感染する可能…
SARS-CoV-2ウイルスの侵入に関わるACE2とTMPRSS2は健康なヒトの呼吸器や角膜や腸管の上皮細胞でも発現していた。鼻の胚細胞や繊毛細胞ではこれらが高発現しており、これらの細胞がウイルス感染の最初の部位で、体内やヒト間でのウイルス拡散の源となっている可能性あり。 https://t.co/oFpOycNijY
RT @NatureMedicine: Mapping the susceptibility of different cell types in the body to #SARSCoV2 infection will help researchers begin to un…
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes | Nature Medicine https://t.co/BMYUPV5ETw
RT @NatureMedicine: Mapping the susceptibility of different cell types in the body to #SARSCoV2 infection will help researchers begin to un…
RT @teichlab: Our first COVID-19 paper by the Lung Biological Network is online at Nature Medicine: SARS-CoV-2 entry factors are highly exp…
RT @EricTopol: Single-cell RNA seq study of healthy tissue to determine the precise path of how #COVID19 enters nose cells https://t.co/i5M…
RT @MC_Nawijn: The Lung Biological Network @humancellatlas paper is out in @NatureMedicine describing epithelial cells of the nasal passag…
RT @NatureMedicine: Mapping the susceptibility of different cell types in the body to #SARSCoV2 infection will help researchers begin to un…
RT @NatureMedicine: Mapping the susceptibility of different cell types in the body to #SARSCoV2 infection will help researchers begin to un…
RT @NatureMedicine: Mapping the susceptibility of different cell types in the body to #SARSCoV2 infection will help researchers begin to un…
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes https://t.co/jxguqGnEkM
RT @Slight_Bright: Nature Medicineにちょうど論文出てた。鼻の胚細胞や粘液産生の繊毛細胞でACE2とTMPRSS2が高発現していることが明らかに、と。>ウイルス学:多数の組織の遺伝学的解析結果は、SARS-CoV-2が鼻の特定の細胞に感染する可能…
RT @Slight_Bright: これは、単に感染者の年齢や基礎疾患などのリスク要因だけでなく、どのように感染したか?という感染経路と、その後の経過も症状に大きく関係するのかも知れんな。#NHKスペシャル https://t.co/BONhJIJn0F
Cifras, gráficos y referencias de por qué llevar mascarilla 1. https://t.co/GwMRdIPyJK 2. https://t.co/zA4Fh9rcAG 3. https://t.co/YaUDegwSOt 4. Modelo textil validado https://t.co/tRsukXz3Lq 5. Incluso una casera de 2capas (calcentín) + TNT (bayeta) es mej
RT @Slight_Bright: これは、単に感染者の年齢や基礎疾患などのリスク要因だけでなく、どのように感染したか?という感染経路と、その後の経過も症状に大きく関係するのかも知れんな。#NHKスペシャル https://t.co/BONhJIJn0F