@lab_leak @Greg21143362 @Rossana38510044 We don’t have a good framework for understanding CoV evolution in bats (it’s probably furiously high, with lots of neutral drift) Codon “optimization” may actually hurt viruses by overloading host translation. http
RT @ymichel: @BallouxFrancois @russ_conser By the way, I've just found a paper which may support the conjecture that the way to produce att…
I've just found a paper which may support the conjecture that "the best way to produce an attenuated virus is to alter its codon usage":https://t.co/6rR8u7kQbe
@BallouxFrancois @russ_conser By the way, I've just found a paper which may support the conjecture that the way to produce attenuated virus is to alter its codon usage: https://t.co/6rR8u7kQbe
RT @JR_Philip_Yang: Virus codon usage should be similar to that of the host, but not excessively so. See our latest research on Nat Ecol E…
RT @AbbeAtSea: If viral codon usage (CU) is too similar to a natural host then host translation efficiency is hampered. So viral CU evolves…
RT @AbbeAtSea: If viral codon usage (CU) is too similar to a natural host then host translation efficiency is hampered. So viral CU evolves…
RT @AbbeAtSea: If viral codon usage (CU) is too similar to a natural host then host translation efficiency is hampered. So viral CU evolves…
RT @AbbeAtSea: If viral codon usage (CU) is too similar to a natural host then host translation efficiency is hampered. So viral CU evolves…
If viral codon usage (CU) is too similar to a natural host then host translation efficiency is hampered. So viral CU evolves towards a sweet-spot. Interestingly, viral CU is more similar to symptomatic v natural hosts. https://t.co/z15X3gda0J @NatureEcoEvo
Coevolution of viruses and their hosts: Infection can affect #codonusage bias 🦠 #CitedEnsembl @NatureEcoEvo https://t.co/SOg37K19J5 #evolution #virology https://t.co/dG7AEHiNxv
RT @NatureEcoEvo: Dissimilation of synonymous codon usage bias in virus–host coevolution due to translational selection https://t.co/G4OuT8…
RT @yokadzaki: Dissimilation of synonymous codon usage bias in virus–host coevolution due to translational selection https://t.co/GoF6sf9apD
RT @NatureEcoEvo: Dissimilation of synonymous codon usage bias in virus–host coevolution due to translational selection https://t.co/G4OuT8…
RT @apicalmavistem: Codon usage in viruses has coevolved such that it matches the host enough (for fast translation) but not so much (such…
RT @JR_Philip_Yang: Virus codon usage should be similar to that of the host, but not excessively so. See our latest research on Nat Ecol E…
RT @apicalmavistem: Codon usage in viruses has coevolved such that it matches the host enough (for fast translation) but not so much (such…
Dissimilation of synonymous codon usage bias in virus–host coevolution due to translational selection | Nature Ecology & Evolution https://t.co/p2Ak3YdpXh
Dissimilation of synonymous codon usage bias in virus–host coevolution due to translational selection https://t.co/GoF6sf9apD
RT @apicalmavistem: Codon usage in viruses has coevolved such that it matches the host enough (for fast translation) but not so much (such…
Codon usage in viruses has coevolved such that it matches the host enough (for fast translation) but not so much (such that translation of host mRNA is not inhibited by viral mRNA). Viruses with highly similar codon usage profiles to their hosts are more l
Dissimilation of synonymous codon usage bias in virus–host coevolution due to translational selection https://t.co/G4OuT835q8 https://t.co/HEYRp1iiWm
RT @JR_Philip_Yang: Virus codon usage should be similar to that of the host, but not excessively so. See our latest research on Nat Ecol E…
Great work!
RT @JR_Philip_Yang: Virus codon usage should be similar to that of the host, but not excessively so. See our latest research on Nat Ecol E…
Virus codon usage should be similar to that of the host, but not excessively so. See our latest research on Nat Ecol Evol https://t.co/zHXFMBK42p