RT @GPR109A: @JaneKoenig5 @JohnConstas …
RT @GPR109A: @CTParent301 @GPR109A ... "Growth arrest in iron-deficient (Fe-def) T cells was prevented upon addition of exogenous iron in t…
RT @GPR109A: @CTParent301 ^ Oh, forgot this one... "niacin, a ligand of @GPR109A, alleviated passive cutaneous anaphylaxis, which was inhi…
RT @IroNiacin: @GPR109A ^ … Here, researchers at the University of Michigan show that Lactobacillus bacteria can sense intestinal iron leve…
RT @IroNiacin: @GPR109A "iron deficiency rather decreased the gut concentration of butyrate and did not alter acetate and propionate levels…
RT @DmitryKatscom: @GPR109A ^ … Here, researchers at the University of Michigan show that Lactobacillus bacteria can sense intestinal iron…
…
RT @DmitryKatscom: "iron deficiency selectively favors the growth or production of microbes"
RT @DmitryKatscom: "iron deficiency selectively favors the growth or production of microbes"
"iron deficiency selectively favors the growth or production of microbes"
RT @DmitryKatscom: @GPR109A "iron deficiency rather decreased the gut concentration of butyrate and did not alter acetate and propionate le…
RT @DrKatscom: @CTParent301 ^ Oh, forgot this one... "niacin, a ligand of @GPR109A, alleviated passive cutaneous anaphylaxis, which was in…
RT @DrKatscom: @CTParent301 @GPR109A ... "Growth arrest in iron-deficient (Fe-def) T cells was prevented upon addition of exogenous iron in…
@ChrisPalmerMD Disgrace
@CTParent301 @GPR109A ... "Growth arrest in iron-deficient (Fe-def) T cells was prevented upon addition of exogenous iron in the form of ferric ammonium citrate" Iron Deprivation in Human T Cells Induces Nonproliferating Accessory Helper Cells https://t.c
RT @DrKatscom: @CTParent301 ^ Oh, forgot this one... "niacin, a ligand of @GPR109A, alleviated passive cutaneous anaphylaxis, which was in…
@CTParent301 ^ Oh, forgot this one... "niacin, a ligand of @GPR109A, alleviated passive cutaneous anaphylaxis, which was inhibited by COX inhibitors & EP3 antagonist" https://t.co/pc1AroUIRY Mast Cells and Their Progenitors in Allergic Asthma https:/
RT @DrKatscom: @GPR109A "iron deficiency rather decreased the gut concentration of butyrate and did not alter acetate and propionate levels…
RT @DrKatscom: @GPR109A "iron deficiency rather decreased the gut concentration of butyrate and did not alter acetate and propionate levels…
RT @DrKatscom: @GPR109A ^ … Here, researchers at the University of Michigan show that Lactobacillus bacteria can sense intestinal iron leve…
@GPR109A ^ … Here, researchers at the University of Michigan show that Lactobacillus bacteria can sense intestinal iron levels and attenuate intestinal iron absorption by the host. Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis
@GPR109A "iron deficiency rather decreased the gut concentration of butyrate and did not alter acetate and propionate levels (Figure S6A)." https://t.co/iDx8o6zwHS https://t.co/47aTJdyziO
^ Supplementary Figure 6. A) SPF mice were fed with 350-ppm and <5- ppm iron diet for 2 weeks, SCFA https://t.co/aXwVRRDXsR "iron deficiency rather decreased the gut concentration of butyrate and did not alter acetate and propionate levels (Figure S6A
RT @DrKatscom: Here, researchers at the University of Michigan show that Lactobacillus bacteria can sense intestinal iron levels and attenu…
Here, researchers at the University of Michigan show that Lactobacillus bacteria can sense intestinal iron levels and attenuate intestinal iron absorption by the host. Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis https://t.co/
筆者たちは、常在菌と宿主の鉄の輸送と貯蔵の関係性を調べました。 腸内細菌叢が、腸内鉄吸収のマスター転写因子の低酸素誘導因子2α(HIF-2α)を抑制し、鉄貯蔵タンパク質フェリチンを増加させる代謝物を生成し、腸内の鉄吸収が低下すること #山田の論文365 その151 https://t.co/S2H6plxEQg
Anemic world where more than 1.5 billion suffer iron deficiency: 'Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis' https://t.co/SLLWqXfZhQ "Lactobacillus species sense intestinal iron levels and attenuate host iron absorption" http
Interesting read. We definitely contain multitudes. https://t.co/W7QlOtGy3b
Our gut microbiota is critical for our health by regulating our iron storage. Check out a recently published paper I worked on: https://t.co/tzmFwe0A0o
Fe absorption- Ca or Lactobacillus? Ca has been studied to block Fe absorption, but results vary, inhibition seems to be stronger with dairy than with Ca supps - https://t.co/T8fOhjuBkI Maybe is not the Ca but the microbiota. https://t.co/5gJGg2IdjX #ca
@Wejumplow @FatEmperor Mostly chicken, fish, shellfish. Very high protein in a CR context is anti-inflammatory, hence iron overload mediating. Conversely, one can have high ferritin from just metS without an HFE. Here's the thread and paper about lactobaci
RT @YukiUehara7: Lactobacillusは腸の鉄レベルを感知し、宿主の鉄吸収を弱める 微生物代謝産物である1,3-diaminopropane (DAP) とロイテリンは、腸の鉄吸収の主な転写因子である低酸素誘導因子2α(HIF-2α)を抑制し、鉄貯蔵タン…
@ptrtwtr @OZmandia @raphaels7 @MactatorMaximus @KetoCarnivore @bendormiki @LogicalLynx @meloegirl @EatLandSalmon @Karageorgos15 @tednaiman @dramerling @DikemanDave @Mangan150 @robbwolf Take a look at intestinal lactobacillus slowing down iron absorption: h
RT @YukiUehara7: Lactobacillusは腸の鉄レベルを感知し、宿主の鉄吸収を弱める 微生物代謝産物である1,3-diaminopropane (DAP) とロイテリンは、腸の鉄吸収の主な転写因子である低酸素誘導因子2α(HIF-2α)を抑制し、鉄貯蔵タン…
RT @YukiUehara7: Lactobacillusは腸の鉄レベルを感知し、宿主の鉄吸収を弱める 微生物代謝産物である1,3-diaminopropane (DAP) とロイテリンは、腸の鉄吸収の主な転写因子である低酸素誘導因子2α(HIF-2α)を抑制し、鉄貯蔵タン…
RT @YukiUehara7: Lactobacillusは腸の鉄レベルを感知し、宿主の鉄吸収を弱める 微生物代謝産物である1,3-diaminopropane (DAP) とロイテリンは、腸の鉄吸収の主な転写因子である低酸素誘導因子2α(HIF-2α)を抑制し、鉄貯蔵タン…
RT @YukiUehara7: Lactobacillusは腸の鉄レベルを感知し、宿主の鉄吸収を弱める 微生物代謝産物である1,3-diaminopropane (DAP) とロイテリンは、腸の鉄吸収の主な転写因子である低酸素誘導因子2α(HIF-2α)を抑制し、鉄貯蔵タン…
Lactobacillusは腸の鉄レベルを感知し、宿主の鉄吸収を弱める 微生物代謝産物である1,3-diaminopropane (DAP) とロイテリンは、腸の鉄吸収の主な転写因子である低酸素誘導因子2α(HIF-2α)を抑制し、鉄貯蔵タンパク質フェリチンを増加させ、宿主の鉄吸収を抑える https://t.co/SuzWZElrzo
RT @KiraNewmanMDPhD: #Microbiome contributes to regulation of host GI iron absorption and can be modified by antibiotics. #IDtwitter and #e…
RT @KiraNewmanMDPhD: #Microbiome contributes to regulation of host GI iron absorption and can be modified by antibiotics. #IDtwitter and #e…
#Microbiome contributes to regulation of host GI iron absorption and can be modified by antibiotics. #IDtwitter and #epitwitter, could this explain some of the benefit of mass Azithromycin administration seen in MORDOR trial? @a2binny https://t.co/2HvCZF
RT @ADreyzen: gut microbiota produce metabolites that suppress hypoxia-inducible factor 2α (HIF-2α) a master transcription factor of intest…
RT @nunoraimundo: Such astonishingly cool study! Gut bacteria compete with the host for iron AND regulate host iron uptake!!! Microbial Me…
RT @digigi60: The gut microbiome is important for everything... Now also for systemic iron metabolism! Microbial Metabolite Signaling Is R…
RT @Cell_Metabolism: Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis https://t.co/J3OhJDBPaK
RT @digigi60: The gut microbiome is important for everything... Now also for systemic iron metabolism! Microbial Metabolite Signaling Is R…
RT @digigi60: The gut microbiome is important for everything... Now also for systemic iron metabolism! Microbial Metabolite Signaling Is R…
RT @digigi60: The gut microbiome is important for everything... Now also for systemic iron metabolism! Microbial Metabolite Signaling Is R…
The gut microbiome is important for everything... Now also for systemic iron metabolism! Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis https://t.co/dHzWxy1E4R
RT @Cell_Metabolism: Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis https://t.co/J3OhJDBPaK
gut microbiota produce metabolites that suppress hypoxia-inducible factor 2α (HIF-2α) a master transcription factor of intestinal iron absorption and increase the iron-storage protein ferritin, resulting in decreased intestinal iron absorption by the host.
RT @Cell_Metabolism: Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis https://t.co/J3OhJDBPaK
RT @Cell_Metabolism: Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis https://t.co/J3OhJDBPaK
RT @Cell_Metabolism: Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis https://t.co/J3OhJDBPaK
RT @gerdosi: Wild speculation, but these findings might establish a close link between the etiologies of metabolic syndrome and iron overlo…
Wild speculation, but these findings might establish a close link between the etiologies of metabolic syndrome and iron overload —in the small intestine.
RT @Cell_Metabolism: Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis https://t.co/J3OhJDBPaK
RT @Cell_Metabolism: Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis https://t.co/J3OhJDBPaK
RT @nunoraimundo: Such astonishingly cool study! Gut bacteria compete with the host for iron AND regulate host iron uptake!!! Microbial Me…
RT @Cell_Metabolism: Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis https://t.co/J3OhJDBPaK
Really amazing work by @nupurkanti and colleagues showing how our microbiome communicates with the host and acquire essential nutrients from us
Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis: Cell Metabolism https://t.co/XkK7vulfqg
RT @Cell_Metabolism: Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis https://t.co/J3OhJDBPaK
Nice work showing that Lactobacillus species sense intestinal iron levels and attenuate host iron absorption.
RT @Cell_Metabolism: Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis https://t.co/J3OhJDBPaK
Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis https://t.co/J3OhJDBPaK
RT @nunoraimundo: Such astonishingly cool study! Gut bacteria compete with the host for iron AND regulate host iron uptake!!! Microbial Me…
RT @nunoraimundo: Such astonishingly cool study! Gut bacteria compete with the host for iron AND regulate host iron uptake!!! Microbial Me…
Such astonishingly cool study! Gut bacteria compete with the host for iron AND regulate host iron uptake!!! Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis https://t.co/qHScexPJJA
Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis https://t.co/gNNfJiFwyF
Microbial Metabolite Signaling Is Required for Systemic Iron Homeostas... https://t.co/n1FZiMiWHb
RT @PubMedTrending: Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis. Cell Metab 2019 #PubmedTrending #PubMed https…
Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis - https://t.co/clkmWhgEdz #ScholarAlerts
Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis. https://t.co/5wGEGOgn2A
Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis. https://t.co/1kNoyUOBgQ
RT @organoidscience: New from @Cell_Metabolism! To explore the underlying mechanism of gut microbiota-mediated inhibition of HIF-2a expres…
RT @organoidscience: New from @Cell_Metabolism! To explore the underlying mechanism of gut microbiota-mediated inhibition of HIF-2a expres…
New from @Cell_Metabolism! To explore the underlying mechanism of gut microbiota-mediated inhibition of HIF-2a expression and function, hPSC-derived intestinal #organoids were generated. @YatrikShahLab https://t.co/BYUVsxEapT https://t.co/ceXNop1Y4F
RT @paulpetertak: Who would have thought that the forgotten organ, the gut microbiome, is involved in systemic iron homeostasis? Fascinatin…
Who would have thought that the forgotten organ, the gut microbiome, is involved in systemic iron homeostasis? Fascinating! An opportunity to translate these insights into small molecule chemistry, bypassing the bugs. https://t.co/4wutdQ90qv!
RT @YatrikShahLab: Microbiota signal to HIF2 for iron regulation! Great work by @nupurkanti and @AndrewJSchwartz. An awesome team helped in…
RT @YatrikShahLab: Microbiota signal to HIF2 for iron regulation! Great work by @nupurkanti and @AndrewJSchwartz. An awesome team helped in…
RT @YatrikShahLab: Microbiota signal to HIF2 for iron regulation! Great work by @nupurkanti and @AndrewJSchwartz. An awesome team helped in…
RT @LyssiotisLab: This is an absolutely phenomenal study from @nupurkanti, @YatrikShahLab. They found a bacterial metabolite that binds a n…
RT @nupurkanti: Our work on Gut microbial regulation on HIF2 and iron metabolism is just out! @YatrikShahLab @AndrewJSchwartz @UMPhysiology…
RT @LyssiotisLab: This is an absolutely phenomenal study from @nupurkanti, @YatrikShahLab. They found a bacterial metabolite that binds a n…
RT @UMPhysiology: A new study in @Cell_Metabolism by @nupurkanti, @AndrewJSchwartz in the @YatrikShahLab shows gut microbiota help sense ir…
RT @YatrikShahLab: Microbiota signal to HIF2 for iron regulation! Great work by @nupurkanti and @AndrewJSchwartz. An awesome team helped in…
RT @YatrikShahLab: Microbiota signal to HIF2 for iron regulation! Great work by @nupurkanti and @AndrewJSchwartz. An awesome team helped in…
RT @YatrikShahLab: Microbiota signal to HIF2 for iron regulation! Great work by @nupurkanti and @AndrewJSchwartz. An awesome team helped in…
RT @YatrikShahLab: Microbiota signal to HIF2 for iron regulation! Great work by @nupurkanti and @AndrewJSchwartz. An awesome team helped in…