🧠Neuro/PADIS💤 Region Second Round Voting #4 ROSE v. #5 PRODEX/MIDEX ROSE: https://t.co/klZWNI2tVP PRODEX/MIDEX: https://t.co/yl2aFYGr1e https://t.co/2rjtPWj2LD
🧠Neuro/PADIS💤 Region #4 ROSE v. #13 MIND-USA ROSE: https://t.co/klZWNI2tVP MIND-USA: https://t.co/j6XkJ5ubDr https://t.co/cgAD42MwoJ
@nickmmark The ROSE ARDS study: https://t.co/RYtrLwG0dC
@TomjRace @Markoaky1 @Jikkyleaks 23 May 2019: ".. avoiding paralysis and deep sedation is the best practice for most patients hospitalized with breathing problems." https://t.co/iJScBmUrvH https://t.co/oGLPVhsbxd
RT @PharmacyToDose: #TrialOfTheDay for May 23rd is the ROSE trial This trial helped answer the question of the role of NMBA in ARDS Open…
RT @PharmacyToDose: #TrialOfTheDay for May 23rd is the ROSE trial This trial helped answer the question of the role of NMBA in ARDS Open…
#TrialOfTheDay for May 23rd is the ROSE trial This trial helped answer the question of the role of NMBA in ARDS Open access article link: https://t.co/klZWNI2tVP #pharmicu #twitterx #pharmem #emrx #ards #pad #medtwitter #meded #some #foamed #foamcc http
@EnjoyerCovid @GSTT_ICU @swhebell @ledot_s @RetterAndrew @Luigi_ICM @AICU_RBH "In the ROSE trial, the patients who received the neuromuscular blockade and sedation developed more cardiovascular issues while in the hospital" https://t.co/iJScBmUrvH https:/
@PandemicAction @WHO @DrTedros @yodifiji @Chikwe_I @MoetiTshidi @WHOAFRO @mvankerkhove 23 May 2019: ".. avoiding paralysis and deep sedation is the best practice for most patients hospitalized with breathing problems." https://t.co/iJScBmUrvH https://t.co
@Jikkyleaks @gmcuk 23 May 2019: "..the trial results make him confident when he says that avoiding paralysis and deep sedation is the best practice for most patients hospitalized with breathing problems." @gmcuk , you knew that in 2019. https://t.co/iJS
Happy to see that medication shortages provode opportunity for quality improvement. No more 48 hour atracurium or cisatracurium drips. Just as needed vecuronium or rocuronium boluses @erin_barreto @kjkpharm @pwierusz @WesElyMD @DrSamuelBrown @DrDaleNeedham
@hswapnil @NephJC_Podcast @captainchloride @kidney_boy @sophia_kidney @doc_faubel @jaykoyner Also best/most recent data suggest that routine paralytics do NOT improve mortality in ARDS. ACURASYS (which showed mortality benefit only on adjusted analysis) ha
RT @accpcritprn: Contradicting the ACURASYS trial, the 2019 ROSE trial found no mortality benefit, and potentially some harm, with neuromu…
RT @accpcritprn: Contradicting the ACURASYS trial, the 2019 ROSE trial found no mortality benefit, and potentially some harm, with neuromu…
Nerumuscular blockade improves oxygenation only after 48 h in moderate, severe ARDS does not reduce ventilator-free days, duration of mechanical ventilation or, most importantly, the mortality risk regardless of the severity of ARDS https://t.co/7xjbHtIqwc
RT @accpcritprn: Contradicting the ACURASYS trial, the 2019 ROSE trial found no mortality benefit, and potentially some harm, with neuromu…
¿Puede el bloqueo neuromusucular temprano en SARS reducir la mortalidad a los 90 días? -ROSE TRIAL- @accpcritprn https://t.co/O9xONOjOSB https://t.co/xEuR9boc5n
RT @accpcritprn: Contradicting the ACURASYS trial, the 2019 ROSE trial found no mortality benefit, and potentially some harm, with neuromu…
RT @accpcritprn: Contradicting the ACURASYS trial, the 2019 ROSE trial found no mortality benefit, and potentially some harm, with neuromu…
RT @accpcritprn: Contradicting the ACURASYS trial, the 2019 ROSE trial found no mortality benefit, and potentially some harm, with neuromu…
Contradicting the ACURASYS trial, the 2019 ROSE trial found no mortality benefit, and potentially some harm, with neuromuscular blockade in early ARDS. #critPRN #PharmICU https://t.co/PGMQWBXf77
Every 🌹 has its thorns https://t.co/NXGbD3gtUl
"Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome" https://t.co/19bbPDrmji #ARDS 筋弛緩薬はルーチンで使うな
@tatonietto @brhospitalist O artigo abaixo certamente não seria discutido, correto? https://t.co/FNBCvH4OIg
RT @ogi_gajic: 4/ Amiodarone pulmonary toxicity responds well to steroids: https://t.co/mc5TJYRmx0 With glucose control (~150) steroids+NMB…
RT @ogi_gajic: 4/ Amiodarone pulmonary toxicity responds well to steroids: https://t.co/mc5TJYRmx0 With glucose control (~150) steroids+NMB…
4/ Amiodarone pulmonary toxicity responds well to steroids: https://t.co/mc5TJYRmx0 With glucose control (~150) steroids+NMB do not cause ⬆️risk of myopathy: https://t.co/ewZjQtobHa https://t.co/3umTPyb8LH https://t.co/pVgRSIaARQ https://t.co/guOkSieiAs ht
2019 Early Neuromuscular Blockade Among patients with ARDS treated with a strategy involving a high PEEP, there was no difference in mortality at 90 days between patients who received cisatracurium and those treated with a usual-care approach https://t.co
@farid__jalali @coolnidal @Sandy95455811 @RozehnalMd @rgbMDPhD 28 day and 90 day mortality showed an average improvement of 19 and 22% respectively in the NMBD groups however the confidence interval on both just clipped the null hypothesis so neither quite
@Rob_Smithers @coolnidal @Sandy95455811 @RozehnalMd @rgbMDPhD Wonder what happened to 28 day and 90 day mortality data there. And the ventilator free days. I guess this one maybe? Those serious CV events don’t matter much? https://t.co/0dk7IW2g2x
RT @PICJournalWatch: @yoncabulutmd @Martin_Kneyber .@yoncabulutmd has summarised this @Martin_Kneyber NBM talk nicely. So, rather than repe…
RT @PICJournalWatch: @yoncabulutmd @Martin_Kneyber .@yoncabulutmd has summarised this @Martin_Kneyber NBM talk nicely. So, rather than repe…
@yoncabulutmd @Martin_Kneyber .@yoncabulutmd has summarised this @Martin_Kneyber NBM talk nicely. So, rather than repeating please find URLs to papers discussed/relevant https://t.co/841DTuvb9N Acuracys/Papazian NEJM 2010 https://t.co/UV8HWZIRcD ROSE tri
RT @iceman_ex: I think this is an incredibly important talk NMBs still have a place. However you need to sit and breathe with the patient…
RT @StephenLap: #CCCF2020 with @nialldferguson on the changing role of neuromuscular blockade, spontaneous breathing & assessing spontaneo…
RT @StephenLap: #CCCF2020 with @nialldferguson on the changing role of neuromuscular blockade, spontaneous breathing & assessing spontaneo…
RT @StephenLap: #CCCF2020 with @nialldferguson on the changing role of neuromuscular blockade, spontaneous breathing & assessing spontaneo…
RT @StephenLap: #CCCF2020 with @nialldferguson on the changing role of neuromuscular blockade, spontaneous breathing & assessing spontaneo…
RT @iceman_ex: I think this is an incredibly important talk NMBs still have a place. However you need to sit and breathe with the patient…
RT @StephenLap: #CCCF2020 with @nialldferguson on the changing role of neuromuscular blockade, spontaneous breathing & assessing spontaneo…
I think this is an incredibly important talk NMBs still have a place. However you need to sit and breathe with the patient to find out where they fit.
RT @StephenLap: #CCCF2020 with @nialldferguson on the changing role of neuromuscular blockade, spontaneous breathing & assessing spontaneo…
RT @StephenLap: #CCCF2020 with @nialldferguson on the changing role of neuromuscular blockade, spontaneous breathing & assessing spontaneo…
RT @StephenLap: #CCCF2020 with @nialldferguson on the changing role of neuromuscular blockade, spontaneous breathing & assessing spontaneo…
RT @StephenLap: #CCCF2020 with @nialldferguson on the changing role of neuromuscular blockade, spontaneous breathing & assessing spontaneo…
RT @StephenLap: #CCCF2020 with @nialldferguson on the changing role of neuromuscular blockade, spontaneous breathing & assessing spontaneo…
RT @StephenLap: #CCCF2020 with @nialldferguson on the changing role of neuromuscular blockade, spontaneous breathing & assessing spontaneo…
#CCCF2020 with @nialldferguson on the changing role of neuromuscular blockade, spontaneous breathing & assessing spontaneous effort in ARDS Big differences between 2 studies: ACURASYS - https://t.co/QvlFJf4mBU ROSE -https://t.co/4l1fdYNoSC https://t.
RT @academiaer1: Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome https://t.co/3LAwkTsGLY @academiaer1 @relucho #FOA…
Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome https://t.co/3LAwkTsGLY @academiaer1 @relucho #FOAMed https://t.co/5AVNQTnXMj
@BrendanNyhan Worse scores will be present for many, perhaps most, patients recovering from profound respiratory failure such as we see after #COVID19 Eg https://t.co/NNHGDtFlNP
ARDS: (ARMA, PROSEVA, ACURASYS, CESAR, EOLIA, PETAL, Driving pressure and survival in ARDS “Amato”) https://t.co/16frvqt8Jn https://t.co/FLh9EHObEJ https://t.co/05mL2FVEmn https://t.co/JQFeswX7UY https://t.co/shEH9PkmHX https://t.co/NhpXPZudoQ http
5. We used semi-structured interviews We enrolled patients from around the nation who had ARDS and had been enrolled in the @NIH_NHLBI RCT of neuromuscular blockade in @NEJM https://t.co/m4BV1RrkBG 79 patients were eligible during our study enrollment,
@respresource @curso_vm @WestPhillyTough @KaminskiMed In the ROSE trial representing good conventional North American practice, average PEEP was 13 on p/F < 150 https://t.co/Mlx2Yki93k https://t.co/Jj3aiDFjR2
Bloqueo neuromuscular en el #SDRA https://t.co/3WJJlEaXqa https://t.co/iaBWtW53Vd
8/Who may require paralysis? Those patients that remain dyssynchronous/hypoxemic despite sedation. Paralysis does not improve mortality in severe ARDS but individual patients may benefit. https://t.co/lAho5zTpYj
RT @PMH_Trauma_RPD: @bbmorshedi While paralysis became one of the cornerstones of ARDS management after the ‘10 NEJM Acurasys trial, I thin…
RT @DrDaleNeedham: After the ROSE trial publication, whose ICUs are regularly using infusion of neuromuscular blocker in early ARDS? https…
RT @DrDaleNeedham: After the ROSE trial publication, whose ICUs are regularly using infusion of neuromuscular blocker in early ARDS? https…
RT @DrDaleNeedham: After the ROSE trial publication, whose ICUs are regularly using infusion of neuromuscular blocker in early ARDS? https…
After the ROSE trial publication, whose ICUs are regularly using infusion of neuromuscular blocker in early ARDS? https://t.co/GTe2zhKq4P @ogi_gajic @DrSamuelBrown @f_g_zampieri @SarinaKS @ICULone @LFerranteMD @efan75 @HeidiEngel4 @Dr_Ridge_DPT
RT @YaleIM_Chiefs: Take-home points: 1. Chronic alcohol use predisposes to #ARDS 2. In ventilated patients with ARDS, data supports pronin…
RT @YaleIM_Chiefs: Take-home points: 1. Chronic alcohol use predisposes to #ARDS 2. In ventilated patients with ARDS, data supports pronin…
Take-home points: 1. Chronic alcohol use predisposes to #ARDS 2. In ventilated patients with ARDS, data supports proning patients 3. Continuous neuromuscular blockade doesn’t improve mortality. See his @NEJM ROSE trial: https://t.co/nBXbrBamRq
RT @drdangayach: #CCC49 ACURASYS Vs. ROSE https://t.co/cSqHv9eRnN https://t.co/e3DfFwoBfv it works in appropriately selected patients, earl…
RT @drdangayach: #CCC49 ACURASYS Vs. ROSE https://t.co/cSqHv9eRnN https://t.co/e3DfFwoBfv it works in appropriately selected patients, earl…
#CCC49 ACURASYS Vs. ROSE https://t.co/cSqHv9eRnN https://t.co/e3DfFwoBfv it works in appropriately selected patients, early IMO @navithadev @SCCM
#CCR20 #ROSE Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome | NEJM https://t.co/Zp1gXMXAFN
RT @_aacw: @Terri_Hough presenting the ROSE trial at #CCR20. https://t.co/kMSUQjE99o.
@Terri_Hough presenting the ROSE trial at #CCR20. https://t.co/kMSUQjE99o.
RT @JMeChua: BBYE Cisatracurium🖐 2010 ➡️ ACURASYS trial: 9% mortality benefit as neuromuscular blocker for ARDS 2019 ➡️ ROSE trial: 🔸️it…
RT @JMeChua: BBYE Cisatracurium🖐 2010 ➡️ ACURASYS trial: 9% mortality benefit as neuromuscular blocker for ARDS 2019 ➡️ ROSE trial: 🔸️it…
BBYE Cisatracurium🖐 2010 ➡️ ACURASYS trial: 9% mortality benefit as neuromuscular blocker for ARDS 2019 ➡️ ROSE trial: 🔸️it didnt really ⬇️mortality vs. modern light sedation protocols ❌ even assoc with #ICU weakness #MedEd #FOAMed #medtwitter https://
RT @acepccmsection: The @nih_nhlbi PETAL network has created some amazing ED-ICU collaborations and brought us the ROSE trial in 2019, demo…
RT @vmoitra: RE: handoffs: if the mental model of the situation is not correct, the actions will not be correct https://t.co/mkElcpR4Jd
RT @iwashyna: #ICUreadings (New med students today on a very very busy service) Foundational: A handoff is not a telegram: an understandi…
RE: handoffs: if the mental model of the situation is not correct, the actions will not be correct
#ICUreadings (New med students today on a very very busy service) Foundational: A handoff is not a telegram: an understanding of the patient is co-constructed via @Crit_Care https://t.co/h3CV1ymTdJ Advanced: NMB for ARDS? surprisingly safe longterm ht
The @nih_nhlbi PETAL network has created some amazing ED-ICU collaborations and brought us the ROSE trial in 2019, demonstrating no benefit of empiric NMB for moderate-severe ARDS 10/ https://t.co/GSr46IuPJo
RT @CritCareReviews: Is neuromuscular blockade beneficial in ARDS? @Terri_Hough presents the #ROSEtrial and @dfmcauley delivers an editori…
RT @CritCareReviews: Is neuromuscular blockade beneficial in ARDS? @Terri_Hough presents the #ROSEtrial and @dfmcauley delivers an editori…
RT @CritCareReviews: Is neuromuscular blockade beneficial in ARDS? @Terri_Hough presents the #ROSEtrial and @dfmcauley delivers an editori…
RT @CritCareReviews: Is neuromuscular blockade beneficial in ARDS? @Terri_Hough presents the #ROSEtrial and @dfmcauley delivers an editori…
RT @CritCareReviews: Is neuromuscular blockade beneficial in ARDS? @Terri_Hough presents the #ROSEtrial and @dfmcauley delivers an editori…
RT @CritCareReviews: Is neuromuscular blockade beneficial in ARDS? @Terri_Hough presents the #ROSEtrial and @dfmcauley delivers an editori…
RT @CritCareReviews: Is neuromuscular blockade beneficial in ARDS? @Terri_Hough presents the #ROSEtrial and @dfmcauley delivers an editori…
RT @CritCareReviews: Is neuromuscular blockade beneficial in ARDS? @Terri_Hough presents the #ROSEtrial and @dfmcauley delivers an editori…
RT @CritCareReviews: Is neuromuscular blockade beneficial in ARDS? @Terri_Hough presents the #ROSEtrial and @dfmcauley delivers an editori…
RT @CritCareReviews: Is neuromuscular blockade beneficial in ARDS? @Terri_Hough presents the #ROSEtrial and @dfmcauley delivers an editori…
RT @CritCareReviews: Is neuromuscular blockade beneficial in ARDS? @Terri_Hough presents the #ROSEtrial and @dfmcauley delivers an editori…
RT @CritCareReviews: Is neuromuscular blockade beneficial in ARDS? @Terri_Hough presents the #ROSEtrial and @dfmcauley delivers an editori…
RT @CritCareReviews: Is neuromuscular blockade beneficial in ARDS? @Terri_Hough presents the #ROSEtrial and @dfmcauley delivers an editori…
RT @CritCareReviews: Is neuromuscular blockade beneficial in ARDS? @Terri_Hough presents the #ROSEtrial and @dfmcauley delivers an editori…