"Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas” Dolan AE [..] Ke A, Zhang Y. Mol Cell. 2019-04-08. https://t.co/USEingYF1z Thermobifida fusca Type I-E CRISPR-Cas system
With Cas3, she can get uni-directional deletions up to 100kb! https://t.co/RV8vXnvSf9
100kbまで飛ばせるらしいからこれ使ったら静岡をKOすれば東京〜名古屋間が40分くらいに https://t.co/reXMNQjRU8
RT @Bio_stations: CRISPR-Cas3による遺伝子改変に成功! Cas9よりも長いゲノム領域をターゲットできるらしい。 dCas3を使えば広いゲノム領域にわたるエピゲノム操作なども可能に! https://t.co/jMLFyDt5Tt
Related work from @AilongK and Yan Zhang @UMich_MCDB shows similar Cascade DNA-targeting complexes from type I CRISPR systems can be combined with Cas3 for creating genomic deletions in human cells. https://t.co/JpIA44Eb1k
Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryo... https://t.co/AUKBUNttOq
https://t.co/szeo2phAtp In case you missed it last month, this is a decent summary of CRISPR-Cas3. Read the paper in @MolecularCell for more: https://t.co/nYfyicOjBf
@ZethSC Besides the recent mol cell paper https://t.co/9qlHFFEy4X. There are almost none available. This is just the beginning of Cas3 as a gene editing tool and the enzyme is currently used from a handful of people that are optimizing it in bacteria and a
RT @fatmike182: Neue CRISPR-Variante (CRISPR/Cas3 von T. fusca) kann auch größere DNA-Stücke bis herausschneiden. Möglicher Einsatz: Herpes…
Neue CRISPR-Variante (CRISPR/Cas3 von T. fusca) kann auch größere DNA-Stücke bis herausschneiden. Möglicher Einsatz: Herpes-Insertionen oä reversieren https://t.co/yZOthk243W #science https://t.co/R5AHbJZ0yW
Pretty cool genetic stuff is going on! Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryo... https://t.co/bLeywPGDmu
Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.co/5szGh1FGfy
CRISPR-Cas3 innovation holds promise for disease cures, advancing science: https://t.co/NDhOrDjEJg https://t.co/hi5gJsJWjr
Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas. https://t.co/gfkc5ibPnK
RT @DrLeoRios: #CRISPR-Cas3, can efficiently erase long stretches of DNA from a targeted site in the human genome, a capability not easily…
#CRISPR-Cas3, can efficiently erase long stretches of DNA from a targeted site in the human genome, a capability not easily attainable in more traditional CRISPR-#Cas9 systems #synbio #syntheticbiology @MolecularCell https://t.co/3tsXH0PO1q https://t.co/a
RT @MolecularCell: Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.c…
Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.co/f20Y8K8IUw 😍🧬✂️
@BKleinstiver Awesome - I want those cards. It’s always good to have a bunch of CRISPR aces up one's sleeve ;-)
Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryo... https://t.co/rLxTI4zKNs
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
Advances in #Biotechnology : New #DNA 'Shredder' #technique goes beyond #CRISPR’s scissors. https://t.co/NDhOrDBg7Q https://t.co/pDm0PNoitt
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
RT @BKleinstiver: Journal club in the #KleinstiverLab today talking about #Class1CRISPR systems, with the assist from @igisci and recent #C…
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
RT @MolecularCell: Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.c…
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
RT @BKleinstiver: Journal club in the #KleinstiverLab today talking about #Class1CRISPR systems, with the assist from @igisci and recent #C…
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
RT @BKleinstiver: Journal club in the #KleinstiverLab today talking about #Class1CRISPR systems, with the assist from @igisci and recent #C…
#CRISPR #Cas used to introduce large #chromosomal #deletions - from a few hundred #basepairs to a hundred kilobases - into #hESC and HAP1 #cells with ~13-60% efficiency https://t.co/8X8ibTZKDh @CellCellPress
Journal club in the #KleinstiverLab today talking about #Class1CRISPR systems, with the assist from @igisci and recent #CRISPR work from @AilongK et al. https://t.co/zU95WqUkuc https://t.co/VjVR0wnfb4
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
RT @CsarDiezV: Yesterday, the first paper using a Class 1 CRISPR-Cas System for gene editing in eukaryotes was published. And, I wanted to…
RT @CsarDiezV: Yesterday, the first paper using a Class 1 CRISPR-Cas System for gene editing in eukaryotes was published. And, I wanted to…
RT @ScienceCrisp: Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I #CRISPR-Cas. Dolan AE […
RT @MolecularCell: Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.c…
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
RT @ScienceCrisp: Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I #CRISPR-Cas. Dolan AE […
RT @Bio_stations: CRISPR-Cas3による遺伝子改変に成功! Cas9よりも長いゲノム領域をターゲットできるらしい。 dCas3を使えば広いゲノム領域にわたるエピゲノム操作なども可能に! https://t.co/jMLFyDt5Tt
RT @Bio_stations: CRISPR-Cas3による遺伝子改変に成功! Cas9よりも長いゲノム領域をターゲットできるらしい。 dCas3を使えば広いゲノム領域にわたるエピゲノム操作なども可能に! https://t.co/jMLFyDt5Tt
RT @Bio_stations: CRISPR-Cas3による遺伝子改変に成功! Cas9よりも長いゲノム領域をターゲットできるらしい。 dCas3を使えば広いゲノム領域にわたるエピゲノム操作なども可能に! https://t.co/jMLFyDt5Tt
RT @MolecularCell: Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.c…
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
Now delete 100 bp by CRISPR /Cas3 the long range editor https://t.co/cYq4namezA https://t.co/nvK6DZWHjB
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas - amazing! 😍 (https://t.co/vzpp6kYa1n)
RT @MolecularCell: Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.c…
RT @GaetanBurgio: This is very interesting paper on the use of type I-E #CRISPR system for gene editing in eukaryote cell line (hESCs) publ…
RT @GaetanBurgio: This is very interesting paper on the use of type I-E #CRISPR system for gene editing in eukaryote cell line (hESCs) publ…
RT @CsarDiezV: Yesterday, the first paper using a Class 1 CRISPR-Cas System for gene editing in eukaryotes was published. And, I wanted to…
RT @dsashital: Great work from Yan Zhang and Ailong Ke labs to use type I-E #CRISPR for creating long range genomic deletions in human cell…
And there are for sure lots of future optimizations and new uses that we can't now imagine. Or maybe not. That's all. I hope some of you have learned a bit about CRISPR-Cas Systems. If you want a little more detail I recommend the following thread. Bye! h
Yesterday, the first paper using a Class 1 CRISPR-Cas System for gene editing in eukaryotes was published. And, I wanted to take the opportunity to explain a little bit what this means. (THREAD) https://t.co/raqI7KxAq6
RT @GaetanBurgio: This is very interesting paper on the use of type I-E #CRISPR system for gene editing in eukaryote cell line (hESCs) publ…
RT @Bio_stations: CRISPR-Cas3による遺伝子改変に成功! Cas9よりも長いゲノム領域をターゲットできるらしい。 dCas3を使えば広いゲノム領域にわたるエピゲノム操作なども可能に! https://t.co/jMLFyDt5Tt
CRISPR-Cas3による遺伝子改変に成功! Cas9よりも長いゲノム領域をターゲットできるらしい。 dCas3を使えば広いゲノム領域にわたるエピゲノム操作なども可能に! https://t.co/jMLFyDt5Tt
RT @GaetanBurgio: This is very interesting paper on the use of type I-E #CRISPR system for gene editing in eukaryote cell line (hESCs) publ…
RT @MolecularCell: Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.c…
RT @GaetanBurgio: This is very interesting paper on the use of type I-E #CRISPR system for gene editing in eukaryote cell line (hESCs) publ…
RT @ScienceCrisp: Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I #CRISPR-Cas. Dolan AE […
Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I #CRISPR-Cas. Dolan AE [..] Ke A, Zhang Y. Mol Cell. 2019-04-08. https://t.co/USEingGvNr
RT @GaetanBurgio: This is very interesting paper on the use of type I-E #CRISPR system for gene editing in eukaryote cell line (hESCs) publ…
This is very interesting paper on the use of type I-E #CRISPR system for gene editing in eukaryote cell line (hESCs) published today in @MolecularCell some really interesting observations https://t.co/r8fsyY03bx https://t.co/ZCzg8dXgLG
RT @MolecularCell: Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.c…
Using Type I CRISPR-Cas systems for genome editing!
RT @MolecularCell: Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.c…
RT @MolecularCell: Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.c…
RT @dsashital: Great work from Yan Zhang and Ailong Ke labs to use type I-E #CRISPR for creating long range genomic deletions in human cell…
RT @dsashital: Great work from Yan Zhang and Ailong Ke labs to use type I-E #CRISPR for creating long range genomic deletions in human cell…
Great work from Yan Zhang and Ailong Ke labs to use type I-E #CRISPR for creating long range genomic deletions in human cells! Cool to see that the activity of Cas3 translates to eukaryotic cells
RT @MolecularCell: Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.c…
RT @MolecularCell: Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.c…
Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.co/EzpRIWCbVc
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
RT @AilongK: Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic…
RT @MolecularCell: Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.c…
RT @MolecularCell: Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.c…
RT @MolecularCell: Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.c…
Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas https://t.co/wUSXr8rB0x
Introducing CRISPR-Cas3, a new genome editor for long-range deletions. Up to 100 kb, demonstrated in human cells. A fantastic collaboration with Dr. Yan Zhang @UMich_MCDB ! #CRISPR https://t.co/Dpr95SygJN https://t.co/U3wfP0w3jG