RT @ichimaruyongo: First 48hours. 治療初期の48時間はCRE上昇が一過性のことが少なくなく、それを基に抗生物質を減量せず、48時間経過後用量を検討した方がよい。 Renal Dosing of Antibiotics: Are We Jumpi…
RT @ichimaruyongo: First 48hours. 治療初期の48時間はCRE上昇が一過性のことが少なくなく、それを基に抗生物質を減量せず、48時間経過後用量を検討した方がよい。 Renal Dosing of Antibiotics: Are We Jumpi…
RT @ichimaruyongo: First 48hours. 治療初期の48時間はCRE上昇が一過性のことが少なくなく、それを基に抗生物質を減量せず、48時間経過後用量を検討した方がよい。 Renal Dosing of Antibiotics: Are We Jumpi…
RT @ichimaruyongo: First 48hours. 治療初期の48時間はCRE上昇が一過性のことが少なくなく、それを基に抗生物質を減量せず、48時間経過後用量を検討した方がよい。 Renal Dosing of Antibiotics: Are We Jumpi…
RT @ichimaruyongo: First 48hours. 治療初期の48時間はCRE上昇が一過性のことが少なくなく、それを基に抗生物質を減量せず、48時間経過後用量を検討した方がよい。 Renal Dosing of Antibiotics: Are We Jumpi…
First 48hours. 治療初期の48時間はCRE上昇が一過性のことが少なくなく、それを基に抗生物質を減量せず、48時間経過後用量を検討した方がよい。 Renal Dosing of Antibiotics: Are We Jumping the Gun? - https://t.co/x5WMLyx474
@IDdocAdi @FarhanFazal10 @Cortes_Penfield @ABsteward @MayoClinicINFD @CarlosdelRio7 @IddocYogiraj @WuidQ @nityanitingupta @pwierusz Should depend on which abx... https://t.co/gVhIwfrxnd
#IDTwitter and #CritCare Twitter, what kind of outcomes would you want to see in a 24hr deferred renal dose adjustment trial of beta-lactams a la this CID article https://t.co/3Dt1DyEVod? ICU population. Would you narrow population further by infection sou
@Tom_MD_ Given that #AKI is a dynamic perturbation, for #antibiotics with wide safety margins, dose adjustment could-in theory-be deferred until 48 hours after initiation of therapy when the trajectory of patient renal function is better characterized http
Hey kidney kids @KidneyCathy @kidney_tom et al, #IDTwitter is promoting 48h deferment of antibiotic dose adjustment for sepsis+AKI, precautionary principle = avoid sub-optimal antibiotic dosing when it counts. What do you neph maddies think for kids? https
Renal Dosing of Antibiotics: Are We Jumping the Gun? | Clinical Infectious Diseases | Oxford Academic https://t.co/jRAj9AmfAT
RT @NuwavePharm: Thoughtful article in the latest @Infectdispract about delaying for 48 hrs renal dosing of ABX in very ill patients with A…
Thoughtful article in the latest @Infectdispract about delaying for 48 hrs renal dosing of ABX in very ill patients with AKI due to risk of underdosing. Like I say to my students: treat the patient, not the CrCl👍 https://t.co/1l8aS1Ap6o
@Roxytonin @tomayates @DrGavinDreyer @bencaplin2 @hswapnil I've got to recommend @DosingMatters Senior author on https://t.co/jkyrQIHCO6
@BIDMC_IM Of course, complicating this even more is the use of Cockcroft-Gault/MDRD in sick patients with AKI. I found this paper to be quite interesting (https://t.co/04JEJYFL1g) -- I'm not entirely convinced we should be renally dosing for every patient
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
RT @Critcare_bear: Too true. It also makes me wonder about the accuracy for prediction when we include creatinine clearance in pk models...…
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
Too true. It also makes me wonder about the accuracy for prediction when we include creatinine clearance in pk models... or are we still looking in the rear view mirror?
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
Reasons to avoid #betalactam dose reduction in #AKI: most #PK data from healthy/stable patients, 1st 48 hrs vital to outcomes, 40-60% of AKI recovers w/in 48 hrs, Scr changes slowly, B-lactams = wide #safety margin. #Wait48? @DrDrayMBA @DHpharmd https
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
RT @MattDavis138: “Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used…
“Thus, antibiotic dosing based on CrCL in AKI is akin to driving a car while looking out the rearview mirror.” Have used this article a ton since I saw it on @IDstewardship thread of best 2018 articles. @SIDPharm @ACCPpostgrads #first48hrs #criticalperiod
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
RT @ABsteward: NEW🔥in CID by @Crasspofungin @DosingMatters Renal Dosing of Antibiotics: Are We Jumping the Gun? The authors suggested that…
@IDstewardship @mmPharmD @BRxAD @KisgenUF @JGPharmD @TheIDApprentice @IDPharmacometrx @khalideljaaly @blandman19 @emilylheil One of the best papers of 2018 definitely.. Practice changing https://t.co/wkiNfCXFID Great work @DosingMatters /@Crasspofungin @BA
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
Such an important topic! Risk vs. benefit is the cornerstone of #transplant #pharmacy where the data is so scant.
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
Renal Dosing of Antibiotics: Are We Jumping the Gun? https://t.co/1P5uoOdsIg via @rightrelevance thanks @hswapnil
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
Very interesting! @BAMPharmD @DosingMatters @Crasspofungin
RT @hswapnil: Amen https://t.co/dtzH99i20a
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
Amen
RT @SIDPharm: Here is a reference to paper by @BAMPharmD with regards to likely premature renal dosing: https://t.co/QlpjvnLKqd
RT @SIDPharm: Here is a reference to paper by @BAMPharmD with regards to likely premature renal dosing: https://t.co/QlpjvnLKqd
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
Here is a reference to paper by @BAMPharmD with regards to likely premature renal dosing: https://t.co/QlpjvnLKqd
RT @ErinMcCreary: Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within…
Data from @Crasspofungin @DosingMatters @BAMPharmD showing the majority of patients with AKI on admission recover within 48 hours— are we jumping the gun in renal dose adjustments of antibiotics? Give. More. Drug. https://t.co/9adOPv39if https://t.co/E8pPi
@BAMPharmD: Over 50% of documented AKI resolves by day 2 of admission on many infectious diagnoses. Indeed we are likely jumping the gun on renal adjustments. Details here: https://t.co/QlpjvnLKqd #ASHP18
RT @farma_gregorio: OJO con la reducción de dosis de antibióticos en IRenal Aguda: plantéate esperar 48 horas! https://t.co/Fsmay7y62o
@FrailetNoelia @Noe_menichelli
RT @farma_gregorio: OJO con la reducción de dosis de antibióticos en IRenal Aguda: plantéate esperar 48 horas! https://t.co/Fsmay7y62o
Renal Dosing of Antibiotics: Are We Jumping the Gun? | Clinical Infectious Diseases | Oxford Academic https://t.co/aoL1iJkML0
RT @farma_gregorio: OJO con la reducción de dosis de antibióticos en IRenal Aguda: plantéate esperar 48 horas! https://t.co/Fsmay7y62o
RT @farma_gregorio: OJO con la reducción de dosis de antibióticos en IRenal Aguda: plantéate esperar 48 horas! https://t.co/Fsmay7y62o
RT @farma_gregorio: OJO con la reducción de dosis de antibióticos en IRenal Aguda: plantéate esperar 48 horas! https://t.co/Fsmay7y62o
RT @farma_gregorio: OJO con la reducción de dosis de antibióticos en IRenal Aguda: plantéate esperar 48 horas! https://t.co/Fsmay7y62o
RT @farma_gregorio: OJO con la reducción de dosis de antibióticos en IRenal Aguda: plantéate esperar 48 horas! https://t.co/Fsmay7y62o
¿Conviene ajustar los AB en IRA en paciente crítico durante las primeras 48h? https://t.co/aHr5XLbJ1T
RT @farma_gregorio: OJO con la reducción de dosis de antibióticos en IRenal Aguda: plantéate esperar 48 horas! https://t.co/Fsmay7y62o
RT @farma_gregorio: OJO con la reducción de dosis de antibióticos en IRenal Aguda: plantéate esperar 48 horas! https://t.co/Fsmay7y62o
RT @merino_salas: Habrá que revisarlo, no? @Farmacia_AS_Pon @UrgPoniente @mi https://t.co/C8vscg8ZuL
RT @farma_gregorio: OJO con la reducción de dosis de antibióticos en IRenal Aguda: plantéate esperar 48 horas! https://t.co/Fsmay7y62o
Habrá que revisarlo, no? @Farmacia_AS_Pon @UrgPoniente @mi
RT @farma_gregorio: OJO con la reducción de dosis de antibióticos en IRenal Aguda: plantéate esperar 48 horas! https://t.co/Fsmay7y62o
RT @farma_gregorio: OJO con la reducción de dosis de antibióticos en IRenal Aguda: plantéate esperar 48 horas! https://t.co/Fsmay7y62o
RT @DosingMatters: This work was inspired by warnings in the labels for newer agents like CAZ/AVI & TOL/TAZ. Important consideration for cl…