| Title |
Brain imaging reveals covert consciousness during behavioral unresponsiveness induced by propofol
|
|---|---|
| Published in |
Scientific Reports, September 2018
|
| DOI | 10.1038/s41598-018-31436-z |
| Pubmed ID | |
| Authors |
Zirui Huang, Phillip E. Vlisides, Vijaykumar C. Tarnal, Ellen L. Janke, Kelley M. Keefe, Margaret M. Collins, Amy M. McKinney, Paul Picton, Richard E. Harris, George A. Mashour, Anthony G. Hudetz |
| Abstract |
Detecting covert consciousness in behaviorally unresponsive patients by brain imaging is of great interest, but a reproducible model and evidence from independent sources is still lacking. Here we demonstrate the possibility of using general anesthetics in a within-subjects study design to test methods or statistical paradigms of assessing covert consciousness. Using noninvasive neuroimaging in healthy volunteers, we identified a healthy study participant who was able to exhibit the specific fMRI signatures of volitional mental imagery while behaviorally unresponsive due to sedation with propofol. Our findings reveal a novel model that may accelerate the development of new approaches to reproducibly detect covert consciousness, which is difficult to achieve in patients with heterogeneous and sometimes clinically unstable neuropathology. |
X Demographics
The data shown below were collected from the profiles of 30 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 6 | 20% |
| United States | 3 | 10% |
| France | 2 | 7% |
| Germany | 1 | 3% |
| Argentina | 1 | 3% |
| Switzerland | 1 | 3% |
| Unknown | 16 | 53% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 22 | 73% |
| Scientists | 4 | 13% |
| Science communicators (journalists, bloggers, editors) | 3 | 10% |
| Practitioners (doctors, other healthcare professionals) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 70 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 14% |
| Student > Master | 9 | 13% |
| Researcher | 8 | 11% |
| Student > Bachelor | 5 | 7% |
| Professor | 3 | 4% |
| Other | 10 | 14% |
| Unknown | 25 | 36% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 13 | 19% |
| Psychology | 10 | 14% |
| Medicine and Dentistry | 5 | 7% |
| Agricultural and Biological Sciences | 3 | 4% |
| Philosophy | 3 | 4% |
| Other | 7 | 10% |
| Unknown | 29 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 61. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 May 2021.
All research outputs
#696,396
of 25,378,162 outputs
Outputs from Scientific Reports
#7,564
of 140,112 outputs
Outputs of similar age
#14,894
of 346,937 outputs
Outputs of similar age from Scientific Reports
#185
of 3,539 outputs
Altmetric has tracked 25,378,162 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 140,112 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.7. This one has done particularly well, scoring higher than 94% of its peers.
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We're also able to compare this research output to 3,539 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.