| Title |
Interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier
|
|---|---|
| Published in |
Nature Reviews Microbiology, June 2018
|
| DOI | 10.1038/s41579-018-0036-x |
| Pubmed ID | |
| Authors |
Eric C. Martens, Mareike Neumann, Mahesh S. Desai |
| Abstract |
The intestinal mucosal barrier is composed of epithelial cells that are protected by an overlying host-secreted mucous layer and functions as the first line of defence against pathogenic and non-pathogenic microorganisms. Some microorganisms have evolved strategies to either survive in the mucosal barrier or circumvent it to establish infection. In this Review, we discuss the current state of knowledge of the complex interactions of commensal microorganisms with the intestinal mucosal barrier, and we discuss strategies used by pathogenic microorganisms to establish infection by either exploiting different epithelial cell lineages or disrupting the mucous layer, as well as the role of defects in mucus production in chronic disease. |
X Demographics
The data shown below were collected from the profiles of 165 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 29 | 18% |
| Spain | 13 | 8% |
| United Kingdom | 11 | 7% |
| France | 10 | 6% |
| Canada | 5 | 3% |
| Netherlands | 3 | 2% |
| Australia | 3 | 2% |
| Brazil | 3 | 2% |
| India | 3 | 2% |
| Other | 23 | 14% |
| Unknown | 62 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 78 | 47% |
| Scientists | 73 | 44% |
| Practitioners (doctors, other healthcare professionals) | 11 | 7% |
| Science communicators (journalists, bloggers, editors) | 3 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 569 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 569 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 119 | 21% |
| Researcher | 90 | 16% |
| Student > Bachelor | 62 | 11% |
| Student > Master | 54 | 9% |
| Student > Doctoral Student | 27 | 5% |
| Other | 76 | 13% |
| Unknown | 141 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 109 | 19% |
| Biochemistry, Genetics and Molecular Biology | 107 | 19% |
| Immunology and Microbiology | 86 | 15% |
| Medicine and Dentistry | 30 | 5% |
| Veterinary Science and Veterinary Medicine | 11 | 2% |
| Other | 57 | 10% |
| Unknown | 169 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 91. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2023.
All research outputs
#476,157
of 25,761,363 outputs
Outputs from Nature Reviews Microbiology
#235
of 2,881 outputs
Outputs of similar age
#10,213
of 343,093 outputs
Outputs of similar age from Nature Reviews Microbiology
#9
of 45 outputs
Altmetric has tracked 25,761,363 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,881 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.9. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 343,093 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 45 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.