| Title |
Transcriptional and post-transcriptional regulation of autophagy in the yeast Saccharomyces cerevisiae
|
|---|---|
| Published in |
Journal of Biological Chemistry, January 2018
|
| DOI | 10.1074/jbc.r117.804641 |
| Pubmed ID | |
| Authors |
Elizabeth Delorme-Axford, Daniel J Klionsky |
| Abstract |
Autophagy is a highly conserved catabolic pathway that is vital for development, cell survival and the degradation of dysfunctional organelles and toxic aggregates. Dysregulation of autophagy is associated with cancer, neurodegeneration and lysosomal storage diseases. Accordingly, autophagy is precisely regulated at multiple levels (transcriptional, post-transcriptional, epigenetic, translational and post-translational) to prevent aberrant activity. Various model organisms exist to study autophagy but the baker's yeast Saccharomyces cerevisiae continues to be very advantageous for genetic and biochemical analysis of non-selective and selective autophagy. In this review, we focus on the cellular mechanisms that regulate autophagy transcriptionally and post-transcriptionally in S. cerevisiae. |
X Demographics
The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 42% |
| United Kingdom | 2 | 17% |
| Nigeria | 1 | 8% |
| Germany | 1 | 8% |
| Mexico | 1 | 8% |
| Unknown | 2 | 17% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 50% |
| Scientists | 6 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 89 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 89 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 28 | 31% |
| Student > Bachelor | 14 | 16% |
| Researcher | 10 | 11% |
| Student > Doctoral Student | 6 | 7% |
| Student > Master | 5 | 6% |
| Other | 5 | 6% |
| Unknown | 21 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 39 | 44% |
| Agricultural and Biological Sciences | 19 | 21% |
| Immunology and Microbiology | 3 | 3% |
| Medicine and Dentistry | 3 | 3% |
| Computer Science | 1 | 1% |
| Other | 2 | 2% |
| Unknown | 22 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 April 2018.
All research outputs
#5,324,067
of 25,729,842 outputs
Outputs from Journal of Biological Chemistry
#13,450
of 85,522 outputs
Outputs of similar age
#108,253
of 452,640 outputs
Outputs of similar age from Journal of Biological Chemistry
#108
of 378 outputs
Altmetric has tracked 25,729,842 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 85,522 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 452,640 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 378 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.