Transcription start site heterogeneity and its role in RNA fate determination https://t.co/6xhZlewPlx @ateles17 Competition and replication assays confirmed that HIV-1 has evolved to rely on the coordinated actions of both its RNA forms.

MCIDT Affiliate Dr. Alice Telesnitsky's (@ateles17) research shows HIV-1 employs diverse transcription start sites (TSSs) to craft two RNA 5´ isoforms with radically different structures and each with specific functions shaping the virus's pathogenesis htt

Transcription start site heterogeneity & role in RNA fate determination distinguish HIV-1 https://t.co/6xhZlewhvZ @ateles17 Competition and replication assays confirmed that HIV-1 has evolved to rely on the coordinated actions of both its RNA forms.

Transcription start site heterogeneity and its role in RNA fate determination distinguish HIV-1 from other retroviruses and are mediated by core promoter elements https://t.co/flraFm4Gac