Amilorides inhibit #SARSCoV2 replication in vitro by targeting RNA structures https://t.co/uTwiB2ME9y
@pamelarbishop Direct-acting antivirals and host-targeting strategies to combat enterovirus infections https://t.co/3jJ9LPECtI Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures https://t.co/uTwiB2ME9y eg. Amiloride https:/
COVID-19: The coronavirus's tangled strands of RNA could offer new ways to treat people who get infected https://t.co/MspyhebOl1 https://t.co/2zd9DJsBil https://t.co/sUGa9UhRaY
RT @EVirusBioinfC: Identification of amiloride-based small molecules that potently #inhibit #SARSCoV2 replication through targeting of cons…
RT @MartinaZaffera1: I am thrilled to share with you our work on SARS-CoV2 antiviral development now published in @ScienceAdvances. In this…
RT @EVirusBioinfC: Identification of amiloride-based small molecules that potently #inhibit #SARSCoV2 replication through targeting of cons…
Identification of amiloride-based small molecules that potently #inhibit #SARSCoV2 replication through targeting of conserved structured elements within the viral 5′-end. [co-authored by EVBC member @paleovirology1] https://t.co/HMFYHCgan6
RT @Sciguy999: New Covid Pills Offer Hope as #Omicron Looms Beyond Merck/Ridgeback’s #molnupiravir, Pfizer’s #Paxlovid @carlzimmer discu…
RT @Sciguy999: New Covid Pills Offer Hope as #Omicron Looms Beyond Merck/Ridgeback’s #molnupiravir, Pfizer’s #Paxlovid @carlzimmer discu…
RT @Sciguy999: New Covid Pills Offer Hope as #Omicron Looms Beyond Merck/Ridgeback’s #molnupiravir, Pfizer’s #Paxlovid @carlzimmer discu…
RT @Sciguy999: New Covid Pills Offer Hope as #Omicron Looms Beyond Merck/Ridgeback’s #molnupiravir, Pfizer’s #Paxlovid @carlzimmer discu…
RT @Sciguy999: New Covid Pills Offer Hope as #Omicron Looms Beyond Merck/Ridgeback’s #molnupiravir, Pfizer’s #Paxlovid @carlzimmer discu…
RT @Sciguy999: New Covid Pills Offer Hope as #Omicron Looms Beyond Merck/Ridgeback’s #molnupiravir, Pfizer’s #Paxlovid @carlzimmer discu…
RT @Sciguy999: New Covid Pills Offer Hope as #Omicron Looms Beyond Merck/Ridgeback’s #molnupiravir, Pfizer’s #Paxlovid @carlzimmer discu…
New Covid Pills Offer Hope as #Omicron Looms Beyond Merck/Ridgeback’s #molnupiravir, Pfizer’s #Paxlovid @carlzimmer discusses @hargrovelab work on drugs targeting #SARSCoV2 RNA 3d structures https://t.co/qTqOQAgpv1 https://t.co/nL1NQeL3wb @DukeChemistry
For more details on this 7-institution #teamscience adventure w/ @MartinaZaffera1 @DukeChemistry, @MeetAChemist @tolbertrnalab, @RWJMS, @JosephYesselman, @seblabk and many others, see the threads below! https://t.co/zGqkpDi9Gp
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @MartinaZaffera1: I am thrilled to share with you our work on SARS-CoV2 antiviral development now published in @ScienceAdvances. In this…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new targets to treat people who get infected. To the unt…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new targets to treat people who get infected. To the unt…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new targets to treat people who get infected. To the unt…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new targets to treat people who get infected. To the unt…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new targets to treat people who get infected. To the unt…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new targets to treat people who get infected. To the unt…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new ways to treat people who get infected. To the untrai…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new targets to treat people who get infected. To the unt…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new targets to treat people who get infected. To the unt…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new targets to treat people who get infected. To the unt…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new targets to treat people who get infected. To the unt…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new targets to treat people who get infected. To the unt…
Blocking RNA: The coronavirus's tangled strands of RNA may offer new targets to treat people who get infected. To the untrained eye SARSCoV2's RNA looks like a wad of tangled yarn. But new sites are being found in the RNA to block replication https://t.co/
RT @MartinaZaffera1: I am thrilled to share with you our work on SARS-CoV2 antiviral development now published in @ScienceAdvances. In this…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new ways to treat people who get infected. To the untrai…
RT @hargrovelab: Detailed 🧵on our collaborative #RNA -targeted #SARSCoV2 work by co-first author @MartinaZaffera1 , who volunteered to synt…
RT @MartinaZaffera1: I am thrilled to share with you our work on SARS-CoV2 antiviral development now published in @ScienceAdvances. In this…
RT @hargrovelab: Detailed 🧵on our collaborative #RNA -targeted #SARSCoV2 work by co-first author @MartinaZaffera1 , who volunteered to synt…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new ways to treat people who get infected. To the untrai…
RT @MartinaZaffera1: I am thrilled to share with you our work on SARS-CoV2 antiviral development now published in @ScienceAdvances. In this…
RT @MartinaZaffera1: I am thrilled to share with you our work on SARS-CoV2 antiviral development now published in @ScienceAdvances. In this…
Detailed 🧵on our collaborative #RNA -targeted #SARSCoV2 work by co-first author @MartinaZaffera1 , who volunteered to synthesize amiloride derivatives in April 2020 - during the lab lockdown - and became a leader on the project 👇
RT @MartinaZaffera1: I am thrilled to share with you our work on SARS-CoV2 antiviral development now published in @ScienceAdvances. In this…
I am thrilled to share with you our work on SARS-CoV2 antiviral development now published in @ScienceAdvances. In this work we developed small molecules that target RNA structures present in the 5’-end of SARS-CoV2 genome (1/9) https://t.co/BRhmKzRkz2
RT @Covid19Nmr: A new paper of the Covid19-NMR project is online! ➡️Amilorides inhibit #SARSCoV2 replication ⬅️ Full text @ScienceAdvances…
RT @Covid19Nmr: A new paper of the Covid19-NMR project is online! ➡️Amilorides inhibit #SARSCoV2 replication ⬅️ Full text @ScienceAdvances…
A new paper of the Covid19-NMR project is online! ➡️Amilorides inhibit #SARSCoV2 replication ⬅️ Full text @ScienceAdvances https://t.co/68bfTHt0nw Spectral raw data @LOGS_Repository https://t.co/cQd5jky7vY Chemical Shifts of SL1 and SL5a @UWbmrb 50346,
Excellent paper on targeting viral 5' UTRs directly with small molecules. Very encouraging.
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new ways to treat people who get infected. To the untrai…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new ways to treat people who get infected. To the untrai…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new ways to treat people who get infected. To the untrai…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new ways to treat people who get infected. To the untrai…
RT @neerajnp: Must read article from @hargrovelab,@tolbertrnalab,@MartinaZaffera1,@MeetAChemist, and co-workers - Amilorides scaffolds targ…
RT @DelthiaRicks: Blocking RNA: The coronavirus's tangled strands of RNA may offer new ways to treat people who get infected. To the untrai…
Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures https://t.co/YWggww9q4n
Blocking RNA: The coronavirus's tangled strands of RNA may offer new ways to treat people who get infected. To the untrained eye SARSCoV2's RNA look like a wad of tangled yarn. But new sites have been found in the RNA to block replication https://t.co/DxgU
RT @neerajnp: Must read article from @hargrovelab,@tolbertrnalab,@MartinaZaffera1,@MeetAChemist, and co-workers - Amilorides scaffolds targ…
RT @neerajnp: Must read article from @hargrovelab,@tolbertrnalab,@MartinaZaffera1,@MeetAChemist, and co-workers - Amilorides scaffolds targ…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
Must read article from @hargrovelab,@tolbertrnalab,@MartinaZaffera1,@MeetAChemist, and co-workers - Amilorides scaffolds targeting the SARS-CoV-2 RNA. Congrats on the paper to all authors - excellent work!!
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
Interesting! Amilorides represent the first antiviral small molecules that target RNA structures within the 5′ untranslated region.
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @MeetAChemist: Proud to work with an exceptional team of scientists! Click to learn more about our SARS-CoV-2 work.
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @nmr900: . @ScienceAdvances (open) Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures, corresponding Mei-Lin…
. @ScienceAdvances (open) Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures, corresponding Mei-Ling Li, Gary Brewer, Blanton S. Tolbert, Amanda E. Hargrove https://t.co/AwXO7yZpjk #NMRchat #NMR
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @MeetAChemist: Proud to work with an exceptional team of scientists! Click to learn more about our SARS-CoV-2 work.
Proud to work with an exceptional team of scientists! Click to learn more about our SARS-CoV-2 work.
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
Researchers are working on new ways to cure COVID-19 infections, using molecules that bind to three-dimensional folds in the virus’s genetic material. Credit: Martina Zafferani, Duke University https://t.co/wvBx1pWzyD https://t.co/kk37UAxUFC
Martina Zafferani et al, Amilorides Inhibit SARS-CoV-2 Replication in vitro by Targeting RNA Structures, Science Advances (2021). DOI: 10.1126/sciadv.abl6096. https://t.co/DQhFsvhBBM https://t.co/dY9wfIRZBn
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures https://t.co/TmVDs2eP7D
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
RT @hargrovelab: Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search…
Excited that our first SARS-CoV-2 RNA-targeting paper is out in @ScienceAdvances! Hopeful it will contribute to the search for new #COVID19 antivirals & targets as well as appreciation for #RNA targeting with small molecules and #teamscience! ⚗️🔬🧪🧬💊 h