RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: What a timing! I was reading and writing about 1KG long-read sequencing efforts last week and today a preprint drops on th…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: What a timing! I was reading and writing about 1KG long-read sequencing efforts last week and today a preprint drops on th…
RT @doctorveera: What a timing! I was reading and writing about 1KG long-read sequencing efforts last week and today a preprint drops on th…
RT @doctorveera: What a timing! I was reading and writing about 1KG long-read sequencing efforts last week and today a preprint drops on th…
RT @doctorveera: What a timing! I was reading and writing about 1KG long-read sequencing efforts last week and today a preprint drops on th…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
What a timing! I was reading and writing about 1KG long-read sequencing efforts last week and today a preprint drops on the LRS of the first 100 individuals from the 1KG. https://t.co/LDZ6CRYTxR
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated by the Human Genome Structural Variation Consortium (HGSVC) (https://t.co/QFfvm8ThWY) 🟥 deCODE Genetics (N=3362; read mapped to GRCh38
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
RT @doctorveera: Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated…
Some of the published long-read sequencing (LRS)-based whole genome datasets: 🟥 1000 genomes (N=64; assembled) generated by the Human Genome Structural Variation Consortium (HGSVC) (https://t.co/QFfvm8ThWY) 🟥 deCODE Genetics (N=3362; read mapped to GRCh38
RT @tangming2005: 8/ Haplotype-resolved diverse human genomes and integrated analysis of structural variation https://t.co/bZVgW555ly
8/ Haplotype-resolved diverse human genomes and integrated analysis of structural variation https://t.co/bZVgW555ly
Re: "Haplotype-resolved diverse human genomes and integrated analysis of structural variation" https://t.co/dRe3lJKSai 2/25/21 Top-down quantum causation linked miRNA-mediated homology to adaptive selection within a human population. Word salad? @Micro
RT @mjpchaisson: When you intersect the SV calls from the last HGSVC paper (https://t.co/f7blKX9Lnz), 61% are in VNTRs! As Adam English say…
RT @mjpchaisson: When you intersect the SV calls from the last HGSVC paper (https://t.co/f7blKX9Lnz), 61% are in VNTRs! As Adam English say…
RT @mjpchaisson: When you intersect the SV calls from the last HGSVC paper (https://t.co/f7blKX9Lnz), 61% are in VNTRs! As Adam English say…
RT @mjpchaisson: When you intersect the SV calls from the last HGSVC paper (https://t.co/f7blKX9Lnz), 61% are in VNTRs! As Adam English say…
RT @mjpchaisson: When you intersect the SV calls from the last HGSVC paper (https://t.co/f7blKX9Lnz), 61% are in VNTRs! As Adam English say…
When you intersect the SV calls from the last HGSVC paper (https://t.co/f7blKX9Lnz), 61% are in VNTRs! As Adam English says "Long-read SVs are VNTRs"
Refreshment of Chapter 1: “Hot L1s, age and coding potential”. 32 haplotype-resolved human genomes. Mmm… let's dig this mine! Older L1s have higher allele frequencies, lower ORF preservation and are therefore less active, but eternal youth can occur https:
Re: mir128 candidacy for 2nd selection site: It lies in R3HDM1, which is most highly expressed in adults in prefrontal cortex, & 3-times higher in fetal brain. Gene GWAS hits incl. grip strength (assoc w cogn) & height. [But I haven’t looked at SNP
Assuming this result is real, I'm wondering what could be the biology. There were two recent reports describing other variants in the locus that may be causal in addition/instead of rs4988235. https://t.co/bgA5FFFD8l https://t.co/6Z1YGnyyi5 5/7
$bngo https://t.co/5cDsVRIIHZ
RT @tobiasmarschal: Human SV resource based on 64 haplotype-resolved assemblies from 25 populations by Human Genome Structural Variation Co…
RT @tobiasmarschal: Human SV resource based on 64 haplotype-resolved assemblies from 25 populations by Human Genome Structural Variation Co…
“We identified 107,590 structural variants (SVs), of which 68% were not discovered with short-read sequencing, and 278 SV hotspots (spanning megabases of gene-rich sequence).”
RT @Magdoll: .@tobiasmarschal : Now w pan-genome can look at population-level SV diffs. not saturated at SV diversity, African descent adds…
RT @Magdoll: .@tobiasmarschal : Now w pan-genome can look at population-level SV diffs. not saturated at SV diversity, African descent adds…
RT @Magdoll: .@tobiasmarschal : Now w pan-genome can look at population-level SV diffs. not saturated at SV diversity, African descent adds…
RT @Magdoll: .@tobiasmarschal : Now w pan-genome can look at population-level SV diffs. not saturated at SV diversity, African descent adds…
RT @Magdoll: .@tobiasmarschal : Now w pan-genome can look at population-level SV diffs. not saturated at SV diversity, African descent adds…
RT @Magdoll: .@tobiasmarschal : Now w pan-genome can look at population-level SV diffs. not saturated at SV diversity, African descent adds…
RT @Magdoll: .@tobiasmarschal : Now w pan-genome can look at population-level SV diffs. not saturated at SV diversity, African descent adds…
RT @Magdoll: .@tobiasmarschal : Now w pan-genome can look at population-level SV diffs. not saturated at SV diversity, African descent adds…
RT @Magdoll: .@tobiasmarschal : Now w pan-genome can look at population-level SV diffs. not saturated at SV diversity, African descent adds…
.@tobiasmarschal : Now w pan-genome can look at population-level SV diffs. not saturated at SV diversity, African descent adds more SVs. @PacBio HiFi asms finds more SVs missed by short reads. some loci very complex. #GI2021 https://t.co/2YIVKkk7ne
@sbarnettARK @JCarterAdams @ciscojmd really? this is news to me - I had assumed that LRS (from PacBio) can only detect 72% of structural variations OGM (from Bionano) does, based on this study. https://t.co/FZjPB3KE5S
Haplotype-resolved diverse human genomes and integrated analysis of structural variation https://t.co/zFR4awPWtE
This looks interesting
Peter Audano: Human genome structural variant consortium (HGSVC) is a group of labs working to improve variant detection methods since many SVs are missed. Published earlier this year: https://t.co/qblCVC2iht #ASHG21
RT @MarkGerstein: @RyanLCollins13 @Phil_A_Richmond @peter_j_park @lh3lh3 @dgmacarthur @tangming2005 I think gnomAD & xTea are the best reso…
RT @MarkGerstein: @RyanLCollins13 @Phil_A_Richmond @peter_j_park @lh3lh3 @dgmacarthur @tangming2005 I think gnomAD & xTea are the best reso…
@RyanLCollins13 @Phil_A_Richmond @peter_j_park @lh3lh3 @dgmacarthur @tangming2005 I think gnomAD & xTea are the best resources for you. That said, you might find something of use in our papers on retrodups (https://t.co/cVdNVLc6cp & https://t.co/0S
Haplotype-resolved diverse human genomes and integrated analysis of structural variation https://t.co/eoVDBIi21U
@cshperspectives @biorxivpreprint I see it now when you hover over the name, but I think it is important to indicate it with an icon without the hover, such as using a star (*) for co-first, and a dagger (‡) for co-corresponding (e.g.https://t.co/6DZi5sg6t
@acarroll_ATG @sbarnettARK PAV (https://t.co/h0FArZ7LuQ) and dipcall (https://t.co/FeiHYX0Huy) are great, too
Applying his methods worldwide: @tobiasmarschal discusses the work of the Human Genome Structural Variation Consortium w/ #SMRTLeiden More info here: https://t.co/Tv7hnwImOP https://t.co/IV4yWDXHrS
RT @BioDecoded: Haplotype-resolved diverse human genomes and integrated analysis of structural variation | Science https://t.co/b6PjvYzhdV…
RT @BioDecoded: Haplotype-resolved diverse human genomes and integrated analysis of structural variation | Science https://t.co/b6PjvYzhdV…
RT @BioDecoded: Haplotype-resolved diverse human genomes and integrated analysis of structural variation | Science https://t.co/b6PjvYzhdV…
Haplotype-resolved diverse human genomes and integrated analysis of structural variation | Science https://t.co/b6PjvYzhdV #Genomics
RT @naturemethods: Research Highlight from Lin Tang: An international team of researchers generate high-quality phased human genome data u…
#DiversityandInclusion in #Genomics. It's a win-win.
RT @naturemethods: Research Highlight from Lin Tang: An international team of researchers generate high-quality phased human genome data u…
RT @naturemethods: Research Highlight from Lin Tang: An international team of researchers generate high-quality phased human genome data u…
Research Highlight from Lin Tang: An international team of researchers generate high-quality phased human genome data using multiple sequencing technologies for comprehensive profiling of structural variation: https://t.co/LT3Fm6upu3 Paper: https://t.co/
https://t.co/rO1MUaQ9kV 30% of all SVs reside on autosomes' last 5 Mbp. The other 70% are mainly scattered across 221 hotspots, relating to genes with huge diversity across populations.
RT @NHGRI_Director: See some of the great work from @mgymrek on the effects of short tandem repeat variation (https://t.co/1QxUXaRXx3) and…
RT @NHGRI_Director: See some of the great work from @mgymrek on the effects of short tandem repeat variation (https://t.co/1QxUXaRXx3) and…
See some of the great work from @mgymrek on the effects of short tandem repeat variation (https://t.co/1QxUXaRXx3) and the HGSVC on larger structural variants (https://t.co/V26DXX2RHV), many of which reside in highly repetitive regions of the human genome.
RT @jyasuda1: 国際1000人ゲノムプロジェクトで、32人(25人種)の全ゲノムをPacBio Sequel IIを使って精細に解析した論文。Science誌。ちゃんと読みたい。 https://t.co/eCBE14aJNt
RT mike_schatz "@EZMoneyBull @JoeButlerUK @sbarnettARK @teaze_r @bvisse @acarroll_ATG @AlbertVilella @PacBio @nanopore @bionanogenomics Here is the link to the final paper: https://t.co/6pe8Fdao6M"
@EZMoneyBull @JoeButlerUK @sbarnettARK @teaze_r @bvisse @acarroll_ATG @AlbertVilella @PacBio @nanopore @bionanogenomics Here is the link to the final paper: https://t.co/RYhA2Q5Dub
Landmark study details sequencing of 64 full human genomes to better capture genetic diversity https://t.co/VRmCLppcmq https://t.co/XfGk0xAcaZ https://t.co/RI342ggLGh
RT @jyasuda1: 国際1000人ゲノムプロジェクトで、32人(25人種)の全ゲノムをPacBio Sequel IIを使って精細に解析した論文。Science誌。ちゃんと読みたい。 https://t.co/eCBE14aJNt
RT @jyasuda1: 国際1000人ゲノムプロジェクトで、32人(25人種)の全ゲノムをPacBio Sequel IIを使って精細に解析した論文。Science誌。ちゃんと読みたい。 https://t.co/eCBE14aJNt
Haplotype-resolved diverse human genomes and integrated analysis of structural variation https://t.co/o9plMkZjFy via @instapaper
Haplotype-resolved diverse human genomes and integrated analysis of structural variation https://t.co/Fzx9v40cIH
RT @eduardopareja: Haplotype-resolved diverse human genomes and integrated analysis of structural variation https://t.co/sY23qjkRsW
Haplotype-resolved diverse human genomes and integrated analysis of structural variation https://t.co/sY23qjkRsW
Haplotype-resolved diverse human genomes and integrated analysis of structural variation https://t.co/aJvWMYGSkA To know more visit : https://t.co/JyG12kQ2jh
RT @jyasuda1: 国際1000人ゲノムプロジェクトで、32人(25人種)の全ゲノムをPacBio Sequel IIを使って精細に解析した論文。Science誌。ちゃんと読みたい。 https://t.co/eCBE14aJNt
RT @THmicroqbio: Pacbioのlong readと、Bionanoのoptical mappingを組み合わせて、これまでのilluminaのshort readでは検出されていなかった染色体上の配列のバラつきを、より高感度で検出。ゲノミクス領域のプレイヤーが…